Cold Spring Harbor Symposia on Quantitative Biology Volume XVI Genes and MutationsPDF电子书下载

Theory of the Gene 1

Goldschmidt,Richard B．Chromosomes and genes 1

McClintock,Barbara．Chromosome organization and genic expression 13

Stadler,L．J．Spontaneous mutation in maize 49

Horowitz,N．H．,and Leupold,Urs．Some recent studies bearing on the one gene-one enzyme hypothesis 65

Cytoplasmic Constituents of Heredity 75

Ephrussi,Boris,and Hottinguer,Helene．On an unstable cell state in yeast 75

Spiegelman,S．The particulate transmission of enzyme-forming capacity in yeast 87

L＇ Heritier,Ph．The Co2 Sensitivity problem in Drosophila 99

Provasoli,Luigi,Hutner,S．H．,and Pintner,Irma J．Destruction of chloroplasts by streptomycin 113

Michaelis,P．Interactions between genes and cytoplasm in Epilobium 121

Evolution of the Gene 131

Stephens,S．G．＂Homologous＂genetic loci in Gossypium 131

Bonner,David M．Gene-enzyme relationships in Neurospora 143

Lewis,E．B．Pseudoallelism and gene evolution 159

Schultz,Jack,and Redfield,Helen．Interchromosomal effects on crossing over in Drosophila 175

Induction of Changes in Genes and Chromosomes Ⅰ 199

Auerbach,Charlotte．Problems in chemical mutagensis 199

Demerec,M．,and Hanson,Jessie．Mutagenic action of manganous chloride 215

Roberts,Richard B．,and Aldous,Elaine．Manganese metabolism of Escherichia coli as related to its mutagenic action 229

Levan,Albert．Chemically induced chromosome reactions in Allium cepa and Vicia faba 233

Jensen,K．A．,Kirk,I．,Kolmark,G．,and Westergaard,M．Chemically induced mutations in Neurospora 245

Induction of Changes in Genes and Chromosomes Ⅱ 263

Gustafsson,Ake．Mutations,environment and evolution 263

Giles,Norman H．,Jr．Studies on the mechanism of reversion in biochemical mutants of Neurospora crassa 283

Hollaender,Alexander,Baker,W．K．,and Anderson,E．H．Effect of oxygen tension and certain chemicals on the X-ray sensitivity of mutation production and survival 315

Russell,W．L．X-ray induced mutations in mice 327

Genetic Mechanisms in Bacteria and Bacterial Viruses Ⅰ 337

Novick,Aaron,and Szilard,Leo．Experiments on spontaneous and chemically induced mutations of bacteria growing in the chemostat 337

Atwood,K．C．,Schneider,Lillian K．,and Ryan,Francis J．Selective mechanisms in basteda 345

Witkin,Evelyn,M．Nuclear segregation and the delayed appearance of induced mutants in Escherichia coli 357

Genetic Mechanisms in Bacteria and Bacterial Viruses Ⅱ 373

Bisset,K．A．Genetical implications of bacterial cytology 376

DeLamater,Edward D．A new cytological basis for bacterial genetics 381

Lederberg,J．,Lederberg,E．M．,Zinder,N．D．,and Lively,E．R．Recombination analysis of bacterial heredity 413

Genetic mechanisms in Bacteria and Bacterial Viruses Ⅲ 445

Ephrussi-Taylor,Harriett．Genetic aspects of transformations of pneumococci 445

Hotchkiss,Rollin D．Transfer of penicillin resistance in pneumococci by the desoxyribonucleate derived from resistant cultures 457

Luria,S．E．The frequency distribution of spontaneous bacteriophage mutants as evidence for the exponential rate of phage reproduction 463

Hershey,A．D．,and Chase,Martha．Genetic recombination and heterozygosis in bacteriophage 471

Concluding Session 481

Mirsky,A．E．Some enzymes of isolated nuclei 481

Sonneborn,T．M．Some current problems of genetics in the light of investigations on Chlamydomonas and Paramecium 483

Appendix 505

Flory,L．E．The television microscope 505