Introduction： There is But One Medicine．＆By WILLIAM D．MALHERBE 467
Part Ⅰ： Some Special Aspects of Metabolic Dyfunction 469
Kinetic Basis of Life Processes： Pathways andMechanisnmofHepatieProtein Synthesis．＆By DAVID L． DR．ABKIN 469
Biochemical Lesions in the Pathogenesis of Geeldikkop （Tribulosis Ovis） and EnzooticIcterus in Sheep in South Africa．＆By J．M．M．BROWN 504
Swine Atherosclerosis： The Relationship of Lipids and Blood Coagulation to Its De-velopnment．＆By H．G．DOWNIE，J．F． MUSTARD AND H．C． ROWSELL 539
Present Concepts Concerning the Origin of Matrix and Stones．＆By WILLIAM H．BOYCE AND J．STANTON KING， JR 563
Part Ⅱ： Metabolic Aspects of Urolithiasis In Man and Animals 579
Immunological Studies on Serum and Urinary Proteins in Urolith Matrix inMan．＆By J． STANTON KING， JR．AND WILLLAM H． BOYCE 579
Silicon Metabolism and Silicon-Protein Matrix Interrelationship in Bovine Urolith-iasis．＆By RICHARD F． KEELER 692
Ion-Competition and the Formation of Phosphatic Uroliths．＆By ROBERT H．UDALLAND Fu Ho CHEN CHOW 612
Renal Calculi Associated with Hyperoxaluria．＆By GEORGE D． LUDWIG 621
Studies on Ovine Urinary Biocolloids and Phosphatic Calculosis．＆By CHARLES E．CORNELIUS 638
Part Ⅲ： The Porphyrias 658
Introduction： Some Historical Highlights in Knowledge of Porphyrins and Por-phyrias．＆By DAVID L． DRABKIN 658
Types of Porphyria： Some Thoughts about Biochemical Mechanisms Involved．＆ByC． RIMINGTON 666
Enzymatic Mechanisms in Porphyrin Synthesis： Possible Enzymatic Blocks in Por-phyries．＆By LAWRENCE BOGORAD 676
Erythrokinetics and Iron Metabolism in Bovine Porphyria Erythropoietica．＆ByJ． J． KANEKO 689
Porphyria In Domestic Animals： Danish Observations in Pigs and Cattle and Com-parison with Human Porphyria．＆By S． K． JφRGENSEN AND TORBEN K．WITH 701
Hyponatremia in Acute Intermittent Porphyria Probably Resulting from Inappro-priate Secretion of Antidiuretic Hormone．＆By GEORGE D． LUDWIG AND MAR-TIN GOLDBERG 710
Part Ⅳ： Ketosis 735
The Biochemistry of Ketosis．＆By RUBIN BRESSLER 735
Hormonal Aspects of Ketosis．＆By FRANK L． ENGEL AND THOMAS T． AMATRUDA， JR 753
Diabetic Ketosis．＆By WALTON W． SHREEVE 772
Fasting Ketosis in the Pregnant Guinea Pig．＆By F． SAUER 787
Ruminant Ketosis： A Speculative Approach．＆By D． S． KRONFELD 799