1.DIGESTION AND ABSORPTION 1
Early experiments 1
Site of absorption 2
Digestion 3
Action of pancreatic lipase 5
Participation of phospholipids 7
Origin and fate of glycerol 9
Determination of state of absorption 10
Absorption of fatty acids as phospholipids 11
Absorption of fatty acids as sterol esters 12
2.TRANSPORT,DEPOSITION AND MOBILIZATION OF FATTY ACIDS 15
Blood transport 15
Deposition 18
Mobilization 21
3.TURNOVER AND METABOLIC INFLUENCES 23
Turnover studies 23
Turnover experiments with acetate 26
Turnover experiments with fatty acids 29
Relationships of carbohydrate and fatty acid metabolism 31
Hormonal influences 34
Fatty acid metabolism in tumors 34
4.BETA OXIDATION OF FATTY ACIDS 37
Acetoacetate formation 37
Conversion to carbohydrate 42
Fatty acid oxidation in plants 43
5.INTERCONVERSIONS OF FATTY ACIDS 46
The saturated and monounsaturated acids 46
The polyunsaturated acids 51
6.BIOSYNTHESIS 57
Fatty acid synthesis in animals 57
Fatty acid synthesis in plants 68
7.PHOSPHOLIPIDS 72
Biosynthesis 74
Catabolism 80
Function 82
8.STEROL ESTERS 88
Sterol esterification during absorption 90
Blood sterol and sterol esters 95
Liver sterol esters 98
Fatty acid spectra of sterol esters 99
9.PROSPECTUS 104
Appendix Ⅰ.Preparation of labeled fatty acids 108
Biosynthesis 108
Laboratory synthesis 110
Appendix Ⅱ.Controlled degradation of labeled fatty acids 119
AUTHOR INDEX 131
SUBJECT INDEX 137