PART Ⅰ THE MOLECULAR DESIGN OF LIFE 1
Chapter 1 Prelude 3
Chapter 2 Biochemical Evolution 19
Chapter 3 Protein Structure and Function 41
Chapter 4 Exploring Proteins 77
Chapter 5 RNA, DNA, and the Flow of Genetic Information 117
Chapter 6 Exploring Genes 143
Chapter 7 Exploring Evolution (including Bioinformatics) 171
Chapter 8 Enzymes: Basic Concepts and Kinetics 189
Chapter 9 Catalytic Strategies 227
Chapter 10 Regulatory Strategies: Enzymes and Hemoglobin 261
Chapter 11 Carbohydrates 295
Chapter 12 Lipids and Cell Membranes 319
Chapter 13 Membrane Channels and Pumps 345
PART Ⅱ TRANSDUCING AND STORING ENERGY 371
Chapter 14 Metabolism: Basic Concepts and Design 373
Chapter 15 Signal-Transduction Pathways: An Introduction to Information Metabolism 395
Chapter 16 Glycolysis and Gluconeogenesis 425
Chapter 17 The Citric Acid Cycle 465
Chapter 18 Oxidative Phosphorylation 491
Chapter 19 The Light Reactions of Photosynthesis 527
Chapter 20 The Calvin Cycle and the Pentose Phosphate Pathway 551
Chapter 21 Glycogen Metabolism 577
Chapter 22 Fatty Acid Metabolism 601
Chapter 23 Protein Turnover and Amino Acid Catabolism 633
PART Ⅲ SYNTHESIZING THE MOLECULES OF LIFE 663
Chapter 24 The Biosynthesis of Amino Acids 665
Chapter 25 Nucleotide Biosynthesis 693
Chapter 26 The Biosynthesis of Membrane Lipids and Steroids 715
Chapter 27 DNA Replication, Recombination, and Repair 745
Chapter 28 RNA Synthesis and Splicing 781
Chapter 29 Protein Synthesis 813
Chapter 30 The Integration of Metabolism 845
Chapter 31 The Control of Gene Expression 867
PART Ⅳ RESPONDING TO ENVIRONMENTAL CHANGES 895
Chapter 32 Sensory Systems 897
Chapter 33 The Immune System 921
Chapter 34 Molecular Motors 951