PART Ⅰ BASICS OF MOLECULAR IMAGING AND NANOBIOTECHNOLOGY 3
1.Basic Principles of Molecular Imaging&Sven H.Hausner 3
2.Synthesis of Nanomaterials as a Platform for Molecular Imaging&Jinhao Gao，Jin Xie，Bing Xu，and Xiaoyuan Chen 25
3.Nanoparticle Surface Modification and Bioconjugation&Jin Xie，Jinhao Gao，Mark Michalski，and Xiaoyuan Chen 47
4.Biodistribution and Pharmacokinetics of Nanoprobes&Nagesh Kolishetti，Frank Alexis，Eric M.Pridgen，and Omid C.Farokhzad 75
PART Ⅱ NANOPARTICLES FOR SINGLE MODALITY MOLECULAR IMAGING 107
5.Computed Tomography as a Tool for Anatomical and Molecular Imaging&Pingyu Liu，Hu Zhou，and Lei Xing 107
6.Carbon Nanotube X-Ray for Dynamic Micro-CT Imaging of Small Animal Models&Otto Zhou，Guohua Cao，Yueh Z.Lee，and Jianping Lu 139
7.Quantum Dots for In Vivo Molecular Imaging&Yun Xing 159
8.Biopolymer，Dendrimer，and Liposome Nanoplatforms for Optical Molecular Imaging&David Pham，Ling Zhang，Bo Chen，and Ella Fung Jones 183
9.Nanoplatforms for Raman Molecular Imaging in Biological Systems&Zhuang Liu 197
10.Single-Walled Carbon Nanotube Near-Infrared Fluorescent Sensors for Biological Systems&Jingqing Zhang and Michael S.Strano 217
11.Microparticle- and Nanoparticle-Based Contrast-Enhanced Ultrasound Imaging&Nirupama Deshpande and Jurgen K.Willmann 233
12.Ultrasound-Based Molecular Imaging Using Nanoagents&Srivalleesha Mallidi，Mohammad Mehrmohammadi，Kimberly Homan，Bo Wang，Min Qu，Tmothy Larson，Konstantin Sokolov，and Stanislav Emelianov 263
13.MRI Contrast Agents Based on Inorganic Nanoparticles&Hyon Bin Na and Taeghwan Hyeon 279
14.Cellular Magnetic Labeling with Iron Oxide Nanoparticles&Sebastien Boutry，Sophie Laurent，Luce Vander Elst，and Robert N.Muller 309
15.Nanoparticles Containing Rare Earth Ions：A Tunable Tool for MRI&C.Riviere，S.Roux，R.Bazzi，J.-L.Bridot，C.Billotey，P.Perriat，and O.Tillement 333
16.Microfabricated Multispectral MRI Contrast Agents&Gary Zabow and Alan Koretsky 375
17.Radiolabeled Nanoplatforms：Imaging Hot Bullets Hitting Their Target&Raffaella Rossin 399
PART Ⅲ NANOPARTICLE PLATFORMS AS MULTIMODALITY IMAGING AND THERAPY AGENTS 433
18.Lipoprotein-Based Nanoplatforms for Cancer Molecular Imaging&Ian R.Corbin，Kenneth Ng，and Gang Zheng 433
19.Protein Cages as Multimode Imaging Agents&Masaki Uchida，Lars Liepold，Mark Young，and Trevor Douglas 463
20.Biomedical Applications of Single-Walled Carbon Nanotubes&Weibo Cai，Ting Gao，and Hao Hong 481
21.Multifunctional Nanoparticles for Multimodal Molecular Imaging&Yanglong Hou and Rui Hao 529
22.Multifunctional Nanoparticles for Cancer Theragnosis&Seulki Lee，Ick Chan Kwon，and Kwangmeyung Kim 541
23.Nanoparticles for Combined Cancer Imaging and Therapy&Vaishali Bagalkot，Mi Kyung Yu，and Sangyong Jon 565
24.Multimodal Imaging and Therapy with Magnetofluorescent Nanoparticles&Jason R.McCarthy and Ralph Weissleder 593
25.Gold Nanocages：A Multifunctional Platform for Molecular Optical Imaging and Photothermal Treatment&Leslie Au，Claire M.Cobley，Jingyi Chen，and Younan Xia 615
26.Theranostic Applications of Gold Nanoparticles in Cancer&Parmeswaran Diagaradjane，Pranshu Mohindra，and Sunil Krishnan 639
27.Gold Nanorods as Theranostic Agents&Alexander Wei，Qingshan Wei，and Alexei P.Leonov 659
28.Theranostic Applications of Gold Core-Shell Structured Nanoparticles&Wei Lu，Marites P.Melancon，and Chun Li 683
29.Magnetic Nanoparticle Carrier for Targeted Drug Delivery：Perspective，Outlook，and Design&R.D.K.Misra 709
30.Perfluorocarbon Nanoparticles：A Multidimensional Platform for Targeted Image-Guided Drug Delivery&Gregory M.Lanza，Shelton D.Caruthers，Anne H.Schmieder，Patrick M.Winter，Tillmann Cyrus，and Samuel A.Wickline 725
31.Radioimmunonanoparticles for Cancer Imaging and Therapy&Arutselvan Natarajan 755
PART Ⅳ TRANSLATIONAL NANOMEDICINE 783
32.Current Status and Future Prospects for Nanoparticle-Based Technology in Human Medicine&Nuria Sanvicens，Fatima Fernaindez，J.-Pablo Salvador，and M.-Pilar Marco 783
Index 815