《METABOLOMICS THE FRONTIER OF SYSTEMS BIOLOGY》PDF下载

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  • 作  者:
  • 出 版 社:SPRINGER
  • 出版年份:2222
  • ISBN:4431251219
  • 页数:256 页
图书介绍:

Part Ⅰ.Introduction 1

Chapter 1:Overview&M.Tomita 1

Part Ⅱ.Analytical Methods for Metabolome Sciences 7

Chapter 2:Development and Application of Capillary Electrophoresis-Mass Spectrometry Methods to Metabolomics&T.Soga 7

Chapter 3:Application of Electrospray Ionization Mass Spectrometry for Metabolomics&R.Taguchi 25

Chapter 4:High-Performance Liquid Chromatography and Liquid Chromatography/Mass Spectrometry Analyses of Metabolites in Microorganisms&H.Miyano 37

Chapter 5:Metabolome Profiling of Human Urine with Capillary Gas Chromatography/Mass Spectrometry&T.Kuhara 53

Chapter 6:Metabolic Profiling by Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry(FT-ICR-MS)and Electrospray Ionization Quadrupole Time-Of-Flight Mass Spectrometry(ESI-Q-TOF-MS)&K.Hirayama 75

Chapter 7:Metabolome Analysis by Capillary Electrophoresis&L.Jia and S.Terabe 91

Chapter 8:High-Performance Liquid Chromatography for Metabolomics:High-Efficiency Separations Utilizing Monolithic Silica Columns&T.Ikegami,H.Kobayashi,H.Kimura,V.V.Tolstikov,O.Fiehn,and N.Tanaka 107

Part Ⅲ.Applications of Metabolome Analysis to Biosciences 127

Chapter 9:Combined Analysis of Metabolome and Transcriptome:Catabolism in Bacillus subtilis&T.Nishioka,K.Matsuda,and Y.Fujita 127

Chapter 10:Metabolomics in Arabidopsis thaliana&K.Saito 141

Chapter 11:Lipidomics:Metabolic Analysis of Phospholipids&R.Taguchi 155

Chapter 12:Chemical Diagnosis of Inborn Errors of Metabolism and Metabolome Analysis of Urine by Capillary Gas Chromatography/Mass Spectrometry&T.Kuhara 167

Part Ⅳ.Metabolome Informatics 193

Chapter 13:Introduction to the ARM Database:Database on Chemical Transformations in Metabolism for Tracing Pathways&M.Arita 193

Chapter 14:The Genome-Based E-CELL Modeling(GEM)System&K.Arakawa,Y.Yamada,K.Shinoda,Y.Nakayama,and M.Tomita 211

Chapter 15:Hybrid Dynamic/Static Method for Large-Scale Simulation of Metabolism and its Implementation to the E-CELL&System&Y.Nakayama 221

Part Ⅴ.Metabolomics and Medical Sciences 233

Chapter 16:Metabolomics and Medical Sciences&T.Nishioka 233

Index 245