1 Acid-Base Concepts 1
2 Structure and Properties of Biologic Molecules 7
3 Protein Structure and Function 19
4 Enzymes and Energetics 29
5 Membranes and Intracellular Signal Transduction 39
6 Glycolysis and Pyruvate Oxidation 49
7 Citric Acid Cycle,Electron Transport Chain,and Oxidative phosphorylation 57
8 Gluconeogenesis and Glycogen Metabolism 67
9 Minor Carbohydrate Pathways:Ribose,Fructose,and Galactose 75
10 Fatty Acid and Triglyceride Metabolism 81
11 Metabolism of Steroids and Other Lipids 89
12 Amino Acid and Heme Metabolism 99
13 Integration of Carbohydrate,Fat,and Amino Acid Metabolism 109
14 Purine,Pyrimidine,and Single-Carbon Metabolism 119
15 Organization,Synthesis,and Repair of DNA 125
16 RNA Transcription and Control of Gene Expression 137
17 Protein Synthesis and Degradation 149
18 Recombinant DNA and Biotechnology 161
19 Nutrition 171
20 Tissue Biochemistry 181
Case Studies 193
Case Study Answers 199
Index 205