第一部分 奋斗历程 1
叶玉如院士简历 3
叶玉如院士的学术历程 4
第二部分 学术贡献 13
一、叶玉如院士的主要学术论文 15
Secretin and Vasoactive Intestinal Peptide Acutely Increase Tyrosine 3-monooxygenase in the Rat Superior Cervical Ganglion 15
Regulation of the Concentration of Adenosine 3′,5′-Cyclic Monophosphate and the Activity of Tyrosine Hydroxylase in the Rat Superior Cervical Ganglion by Three Neuropeptides of the Secretin Family 22
Identification and Characterization of a Hypervariable Region [D18S27] on Chromosome 18 35
Discovery of a Novel Multilocus DNA Polymorphism [DNF24] 36
Ciliary Neurotrophic Factor Enhances Neuronal Survival in Embryonic Rat Hippocampal Cultures 38
Mammalian Neurotrophin-4: Structure, Chromosomal Localization, Tissue Distribution,and Receptor Specificity 52
Similarities and Differences in the Way Neurotrophins Interact with the Trk Receptors in Neuronal and Nonneuronal Cells 60
Potentiation of Developing Neuromuscular Synapses by the Neurotrophins NT-3 and BDNF 75
Cultured Hippocampal Neurons Show Responses to BDNF, NT-3, and NT-4,but Not NGF 80
The Neurotrophins and CNTF: Two Families of Collaborative Neurotrophic Factors 95
Cdk5 is Involved in Neuregulin-induced AChR Expression at the Neuromuscular Junction 111
Central Synapse and Neuromuscular Junction: Same Players, Different Roles 123
Cyclin-dependent Kinase 5 Phosphorylates Signal Transducer and Activator of Transcription 3 and Regulates its Transcriptional Activity 134
α-Syntrophin Regulates ARMS Localization at the Neuromuscular Junction and Enhances EphA4 Signaling in an ARMS-dependent Manner 144
Agrin Regulates Growth Cone Turning of Xenopus Spinal Motoneurons 162
Aberrant Motor Axon Projection, Acetylcholine Receptor Clustering, and Neurotransmission in Cyclin-dependent Kinase 5 Null Mice 173
Synaptic Roles of Cdk5: Implications in Higher Cognitive Functions and Neurodegenerative Diseases 183
Cyclin-dependent Kinase 5 Links Extracellular Cues to Actin Cytoskeleton during Dendritic Spine Development 191
Cdk5 is Involved in BDNF-stimulated Dendritic Growth in Hippocampal Neurons 195
α2-Chimaerin Interacts with EphA4 and Regulates EphA4-dependent Growth Cone Collapse 211
β-Catenin in Reverse Action 220
Cyclin-dependent Kinase 5 Supports Neuronal Survival through Phosphorylation of Bcl-2 223
Endophilin Bl as a Novel Regulator of Nerve Growth Factor/TrkA Trafficking and Neurite Outgrowth 232
Synapse Development and Plasticity: Roles of Ephrin/Eph Receptor Signaling 248
Ephexinl is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction 258
Tyk2/STAT3 Signaling Mediates β-Amyloid-induced Neuronal Cell Death:Implications in Alzheimer′s Disease 275
Two Cyclin-dependent Kinase Pathways are Essential for Polarized Trafficking of Presynaptic Components 289
S-Nitrosylation of Cyclin-dependent Kinase 5 (Cdk5) Regulates its Kinase Activity and Dendrite Growth during Neuronal Development 306
APCcdhl Mediates EphA4-dependent Downregulation of AMPA Receptors in Homeostatic Plasticity 314
Cdk5-mediated Phosphorylation of Endophilin B1 is Required for Induced Autophagy in Models of Parkinson′s Disease 331
Career Development for Women Scientists in Asia 355
Cdk5-mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development 360
Cdk5: a Multifaceted Kinase in Neurodegenerative Diseases 378
α2-Chimaerin Controls Neuronal Migration and Functioning of the Cerebral Cortex through CRMP-2 387
Molecular Mechanisms Underlying Maturation and Maintenance of the Vertebrate Neuromuscular Junction 404
Ankyrin Repeat-rich Membrane Spanning Protein (Kidins220) is Required for Neurotrophin and Ephrin Receptor-dependent Dendrite Development 421
TrkB Phosphorylation by Cdk5 is Required for Activity-dependent Structural Plasticity and Spatial Memory 432
Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-dependent Mechanism 452
二、叶玉如院士学术年表 465
第三部分 人生风采 471