《叶玉如院士集》PDF下载

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  • 作  者:叶玉如主编;香港科技大学编著;陈宇秘书
  • 出 版 社:北京:人民军医出版社
  • 出版年份:2014
  • ISBN:9787509176832
  • 页数:484 页
图书介绍:本书是《中国医学院士文库》的分册之一。本书由五部分组成。第一部分奋斗历程,介绍了院士的主要经历和事业发展的宝贵经验;第二部分学术贡献,包括院士的主要学术论文、学术著作以及学术年表等,反映了院士在理论创新和技术进步方面的主要成果及其价值;第三部分治学之道,阐述了院士的创新意识、严谨作风和刻苦精神;第第四部分社会评价和赞誉;第五部分人生风采,以丰富的图片资料展示了院士在不同时期工作、国际交流和业余生活等方方面面的风采。全书充分诠释了院士的学术成就、学术思想和学术风范,可供广大医学工作者,特别是从事遗传免疫的专业人员学习、借鉴

第一部分 奋斗历程 1

叶玉如院士简历 3

叶玉如院士的学术历程 4

第二部分 学术贡献 13

一、叶玉如院士的主要学术论文 15

Secretin and Vasoactive Intestinal Peptide Acutely Increase Tyrosine 3-monooxygenase in the Rat Superior Cervical Ganglion 15

Regulation of the Concentration of Adenosine 3′,5′-Cyclic Monophosphate and the Activity of Tyrosine Hydroxylase in the Rat Superior Cervical Ganglion by Three Neuropeptides of the Secretin Family 22

Identification and Characterization of a Hypervariable Region [D18S27] on Chromosome 18 35

Discovery of a Novel Multilocus DNA Polymorphism [DNF24] 36

Ciliary Neurotrophic Factor Enhances Neuronal Survival in Embryonic Rat Hippocampal Cultures 38

Mammalian Neurotrophin-4: Structure, Chromosomal Localization, Tissue Distribution,and Receptor Specificity 52

Similarities and Differences in the Way Neurotrophins Interact with the Trk Receptors in Neuronal and Nonneuronal Cells 60

Potentiation of Developing Neuromuscular Synapses by the Neurotrophins NT-3 and BDNF 75

Cultured Hippocampal Neurons Show Responses to BDNF, NT-3, and NT-4,but Not NGF 80

The Neurotrophins and CNTF: Two Families of Collaborative Neurotrophic Factors 95

Cdk5 is Involved in Neuregulin-induced AChR Expression at the Neuromuscular Junction 111

Central Synapse and Neuromuscular Junction: Same Players, Different Roles 123

Cyclin-dependent Kinase 5 Phosphorylates Signal Transducer and Activator of Transcription 3 and Regulates its Transcriptional Activity 134

α-Syntrophin Regulates ARMS Localization at the Neuromuscular Junction and Enhances EphA4 Signaling in an ARMS-dependent Manner 144

Agrin Regulates Growth Cone Turning of Xenopus Spinal Motoneurons 162

Aberrant Motor Axon Projection, Acetylcholine Receptor Clustering, and Neurotransmission in Cyclin-dependent Kinase 5 Null Mice 173

Synaptic Roles of Cdk5: Implications in Higher Cognitive Functions and Neurodegenerative Diseases 183

Cyclin-dependent Kinase 5 Links Extracellular Cues to Actin Cytoskeleton during Dendritic Spine Development 191

Cdk5 is Involved in BDNF-stimulated Dendritic Growth in Hippocampal Neurons 195

α2-Chimaerin Interacts with EphA4 and Regulates EphA4-dependent Growth Cone Collapse 211

β-Catenin in Reverse Action 220

Cyclin-dependent Kinase 5 Supports Neuronal Survival through Phosphorylation of Bcl-2 223

Endophilin Bl as a Novel Regulator of Nerve Growth Factor/TrkA Trafficking and Neurite Outgrowth 232

Synapse Development and Plasticity: Roles of Ephrin/Eph Receptor Signaling 248

Ephexinl is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction 258

Tyk2/STAT3 Signaling Mediates β-Amyloid-induced Neuronal Cell Death:Implications in Alzheimer′s Disease 275

Two Cyclin-dependent Kinase Pathways are Essential for Polarized Trafficking of Presynaptic Components 289

S-Nitrosylation of Cyclin-dependent Kinase 5 (Cdk5) Regulates its Kinase Activity and Dendrite Growth during Neuronal Development 306

APCcdhl Mediates EphA4-dependent Downregulation of AMPA Receptors in Homeostatic Plasticity 314

Cdk5-mediated Phosphorylation of Endophilin B1 is Required for Induced Autophagy in Models of Parkinson′s Disease 331

Career Development for Women Scientists in Asia 355

Cdk5-mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development 360

Cdk5: a Multifaceted Kinase in Neurodegenerative Diseases 378

α2-Chimaerin Controls Neuronal Migration and Functioning of the Cerebral Cortex through CRMP-2 387

Molecular Mechanisms Underlying Maturation and Maintenance of the Vertebrate Neuromuscular Junction 404

Ankyrin Repeat-rich Membrane Spanning Protein (Kidins220) is Required for Neurotrophin and Ephrin Receptor-dependent Dendrite Development 421

TrkB Phosphorylation by Cdk5 is Required for Activity-dependent Structural Plasticity and Spatial Memory 432

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-dependent Mechanism 452

二、叶玉如院士学术年表 465

第三部分 人生风采 471