第一部分 奋斗历程 1
曾毅院士成长大事记 3
第二部分 学术贡献 7
一、曾毅院士主要学术成就和学术思想 9
肿瘤病毒和艾滋病病毒的研究及其防治领域的开拓者 9
二、曾毅院士代表性学术论文 11
Establishment of an Epithelioid Cell Line and a Fusiform Cell Line from a Patient withNasopharyngeal Carcinoma① 11
Application of an Immunoenzymatic Method and an Immunoautoradiograhic Methodfor a Mass Survey of Nasopharyngeal Carcinoma 20
Development of an Anticomplement Immunoenzyme Test for Detection of EB VirusNuclear Antigen（EBNA） and Antibody to EBNA 25
Inhibitory Effect of Retinoids on Epstein-Barr Virus Induction in Raji Cells 28
Serological Mass Survey for Early Detection of Nasopharyngeal Carcinoma in Wuzhou City，China 31
Follow-up Studies on Epstein-Barr Virus IgA/VCA Antibody-Positive Persons inZangwu County，China 35
Epstein-Barr Virus Early Antigen Induction in Raji Cells by Chinese Medicinal Herbs 39
Epstein-Barr Virus-Activating Principle in the Ether Extracts of Soils Collected fromunder Plants which Contain Active Diterpene Esters 43
Comparative Evaluation of Various Techniques to Detect EBV DNA in ExfoliatedNasopharyngeal Cells 47
Detection of Epstein-Barr Virus IgA/EA Antibody for Diagnosis of NasopharyngealCarcinoma by immunoautoradiography 53
Presence of EBV-DNA Sequences in Nasopharyngeal Cells of Individuals withoutIgA-VCA Antibodies 57
Early Nasopharyngeal Carcinoma Among IgA/VCA Antibody Positive IndividualsDetected by Anticomplement Immunoenzymatic Method 62
HTLV Antibody in China 65
Epstein-Barr Virus Activation in Raji Cells with Ether Extracts of Soil from DifferentAreas in China 66
Epstein-Barr Virus Activation by Human Semen Principle： Synergistic Effect of Culture Fluids of Bacteria Isolated from Patients with Carcinoma of Uterine Cervix 70
Prospective Studies on Nasopharyngeal Carcinoma in Epstein-Barr Virus IgA/VCA Antibody-Positive Persons in Wuzhou City，China 73
Seroepidemiological studies on Nasopharyngeal Carcinoma in China 77
Nasopharyngeal Carcinoma：Early Detection and IgA-Related pre-NPC Condition，Achievements and Prospectives 86
Nasopharyngeal Mucosal Changes in EB Virus VCA-IgA Antibody Positive Persons 91
ELISA for the Detection of Nasopharyngeal Carcinoma Using IgA Antibodies to EBV Early Antigen 96
Detection of IgG and IgA Antibodies to Epstein-Barr Virus Membrane Antigen in Sera from Patients with Nasopharyngeal Carcinoma and from Normal Individuals 102
Epstein-Barr Virus Activation in Raji Cells by Extracts of Preserved Food from High Risk Areas for Nasopharyngeal Carcinoma 105
Wikstroemia Indica Promotes Development of Nasopharyngeal Carcinoma in Rats Initiated by Dinitrosopiperazine 108
Linkage of a Nasopharyngeal Carcinoma Susceptibility Locus to the HLA Region 111
Diagnosis of Nasopharyngeal Carcinoma by Means of Recombinant Epstein-Barr Virus Proteins 114
Salivary and Serum IgA Antibodies to the Epstein-Barr Virus Glycoprotein gp340：Incidence and Potential for Virus Neutralization 120
Detection of Anti-Epstein-Barr-Virus Transactivator（Zebra） Antibodies in Sera from Patients with Nasopharyngeal Carcinoma 128
A Research for the Relationship between Human Papillomavirus and Human Uterine Cervical Carcinoma 132
A Research for the Relationship between Human Papillomavirus and Human Uterine Cervical Carcinoma 140
Suppression of Human Nasopharyngeal Carcinoma Cell Growth in Nude Mice by the Wild-Type p53 Gene 152
A 10-Year Prospective Study on Nasopharyngeal Carcinoma in Wuzhou City and Zangwu County， Guangxi，China 156
Urinary Excretion of Nitrosamino Acids and Nitrate by Inhabitants of High and Low Risk Areas for Nasopharyngeal Carcinoma in Southern China 161
Environmental and Dietary Risk Factors for Nasopharyngeal Carcinoma：A Case- Control Study in Zangwu County，Guangxi，China 168
Establishment of a Human Malignant T Lymphoma Cell Line Carrying a Retrovirus- like Particle with RT Activity 178
Screening of Epstein-Barr Virus Early Antigen Expression Inducers from Chinese Medicinal Herbs and Plants 186
Serological Survey of Nasopharyngeal Carcinoma in 21 Cities of South China 191
Detection of Epstein-Barr Virus DNA in well and Poorly Differentiated Nasopharyngeal Carcinoma Cell Lines 195
Epstein-Barr Virus Strain Variation in Nasopharyngeal Carcinoma from the Endemic and Non-Endemic Regions of China 201
Synergistic Effect of Epstein-Barr Virus and Tumor Promoters on Induction of Lymphoma and Carcinoma in Nude Mice 214
Study of Immortalization and Malignant Transformation of Human Embryonic Esophageal Epithelial Cells Induced by HPV18 E6E7 221
Detection of Human Papillomavirus in Esophageal Carcinoma 228
Progressive Transformation of Immortalized Esophageal Epitbelial Cells 234
The Multistage Process of Carcinogenesis in Human Esophageal Epithelial Cells Induced by Human Papillomavirus 241
Malignant Transformation of Human Embryonic Liver Cells Induced by Hepatitis B Virus and Aflatoxin B1 251
Construction and Characterization of Chimeric BHIV（BIV/HIV-1）Viruses Carrying the Bovine Immunodeficiency Virus Gag Gene 257
Induction of Cytotoxic T Lymphocyte Respones in vivo after Immunotherapy with Dendritic Cells in Patients with Nasopharyngeal Carcinoma 265
In vitro Anti-Tumor Immune Response Induced by Dendritic Cells Transfected withEBV-LMP2 Recombinant Adenovirus 272
Immunogenicity of the Recombinant Adenovirus Type 5 Vector with Type 35 Fiber Containing HIV-1 Gag Gene 280
Haplotype-dependent HLA Susceptibility to Nasopharyngeal Carcinoma in a Southern Chinese Population 286
The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove 297
Phylogenetic and Temporal Dynamics of Human Immunodeficiency Virus Type 1 CRF01 AE in China 310
Haplotype-dependent HLA Susceptibility to Nasopharyngeal Carcinoma in a Southern Chinese Population 318
三、曾毅院士学术年表 329
曾毅院士中文论文目录 329
曾毅院士英文论文目录 356
曾毅院士主要获奖奖项 370
第三部分 大师风范 373
巍巍科山不老松 375
科学青春永驻 378
鸿儒硕学 高瞻远瞩 379
毅者人生 381
曾毅：只为挽救更多生命 384
快乐老人的预防哲学 388
A Controversial Bid to Thwart the “Cantonese Cancer” 389
第四部分 社会影响 393
普查人类癌症的第一个例证 395
这是首次证明EB病毒可以在体内诱发实验性癌症 396
对鼻咽癌细胞中EB病毒标记的阐述是举世无双的 398
当代医学上的一个里程碑 400
曾毅教授的贡献值得国际、国内科学界的承认和赞扬 402
中国科学院贺信 404
第五部分 人生风采 405
科研工作 407
国际交流 409
重要时刻 415
珍贵合影 417
幸福生活 418