1 Biomedical Nanotechnology&Sarah J.Hurst 1
PART Ⅰ USING NANOMATERIALS IN SENSING,IMAGING,AND THERAPEUTICS 17
2 Multiplexed Detection of Oligonucleotides with Biobarcoded Gold Nanoparticle Probes&Jae-Seung Lee 17
3 Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance&Jered B.Haun,Tae-Jong Yoon,Hakho Lee,and Ralph Weissleder 33
4 Real-Time Quantum Dot Tracking of Single Proteins&Jerry C.Chang and Sandra J.Rosenthal 51
5 Titanium Dioxide Nanoparticles in Advanced Imaging and Nanotherapeutics&Tijana Rajh,Nada M.Dimitrijevic,and Elena A.Rozhkova 63
6 Surface Modification and Biomolecule Immobilization on Polymer Spheres for Biosensing Applications&Chris R.Taitt,Lisa C.Shriver-Lake,George P.Anderson,and Frances S.Ligler 77
7 Multivalent Conjugation of Peptides,Proteins,and DNA to Semiconductor Quantum Dots&Duane E.Prasuhn,Kimihiro Susumu,and Igor L.Medintz 95
8 A Single SnO2 Nanowire-Based Microelectrode&Jun Zhou,Yaguang Wei,Qin Kuang,and Zhong Lin Wang 111
9 Biosensing Using Nanoelectromechanical Systems&Ashish Yeri and Di Gao 119
10 Nano"Fly Paper"Technology for the Capture of Circulating Tumor Cells&Shutao Wang,Gwen E.Owens,and Hsian-Rong Tseng 141
11 Polymeric Nanoparticles for Photodynamic Therapy&Yong-Eun Koo Lee and Raoul Kopelman 151
12 Hydrogel Templates for the Fabrication of Homogeneous Polymer Microparticles&Ghanashyam Acharya,Matthew Mc Dermott,Soo Jung Shin,Haesun Park,and Kiham Park 179
13 Antibacterial Application of Engineered Bacteriophage Nanomedicines:Antibody-Targeted,Chloramphenicol Prodrug Loaded Bacteriophages for Inhibiting the Growth of Staphylococcus aureus Bacteria&Lilach Vaks and Itai Benhar 187
14 Viruses as Nanomaterials for Drug Delivery&Dustin Lockney,Stefan Franzen,and Steven Lommel 207
15 Applications of Carbon Nanotubes in Biomedical Studies&Hongwei Liao,Bhavna Paratala,Balaji Sitharaman,and Yuhuang Wang 223
16 Electrospun Nanofibrous Seaffolds for Engineering Soft Connective Tissues&Roshan James,Udaya s.Toti,Cato T.Laurencin,and Sangamesh G.Kumbar 243
17 Peptide Amphiphiles and Porous Biodegradable Seaffolds for Tissue Regeneration in the Brain and Spinal Cord&Rutledge G.Ellis-Behnke and Gerald E.Schneider 259
18 Computational Simulations of the Interaction of Lipid Membranes with DNA-Functionalized Gold Nanoparticles&One-Sun Lee and George C.Schatz 283
PART Ⅱ TRANSLATING NANOSCIENCE AND TECHNOLOGY FROM THE LAB TO THE CLINIC 299
19 Cytotoxic Assessment of Carbon Nanotube Interaction with Cell Cultures&Hanene Ali-Boucetta,Khuloud T.Al-Jamal,and Kostas Kostarelos 299
20 Nanoparticle Toxicology:Measurements of Pulmonary Hazard Effects Following Exposures to Nanoparticles&Christie M.Sayes,Kenneth L Reed,and David B.Warheit 313
21 Nanoparticle Therapeutics:FDA Approval、Clinical Trials、Regulatory Pathways,and Case Study&Aaron C.Eiflerand C.Shad Thaxton 325
22 Legislating the Laboratory?Promotion and Precaution in a Nanomaterials Company&Robin Phelps and Erik Fisher 339
23 Navigating the Patent Landscapes for Nanotechnology:English Gardens or Tangled Grounds?&Douglas J.Sylvester and Diana M.Bowman 359
24 Scientific Entrepreneurship in the Materials and Life Science Industries&Jose Amade Dinglasan,Darren J.Anderson,and Keith Thomas 379
25 Applying the Marketing Mix(5 Ps)to Bionanotechnology&Michael S.Tomczyk 393
26 Managing the"Known Unknowns":Theranostic Cancer Nanomedicine and Informed Consent&Fabrice Jotterand and Archie A.Alexander 413
Index 431