第一部分:总论 3
药物动力学 3
抗生素的体外敏感试验 12
如何选择适当的抗生素 15
抗生素治疗失败 24
台湾的抗药性现况与经验性抗生素的改变 31
抗药性细菌的治疗 36
肝、肾功能不全病患的抗生素使用 44
怀孕的抗生素使用 47
第二部分:抗生素各论 51
β -lactams 51
Penicillin G 53
Oxacillin 57
Dicloxacillin、Cloxacillin 60
Ampicillin 62
Amoxicillin 64
Piperacillin 68
β-lactam/β-lactamase inhibitors 71
Augmentin (amoxicillin-clavulanate) 75
Unasyn (ampicillin-sulbactam) 81
Tazocin (piperacillin-tazobactam) 83
Cefazolin 88
Cephalexin (Keflex) 92
Cephradine 95
Cefuroxime 97
Cephamycins 102
Cefoxitin 106
Cefmetazole 107
Cefotetan 108
Flomoxef (Flumarin) 110
第三代cephalosporins 112
Cefotaxime (Claforan) 117
Ceftriaxone (Rocephin) 119
Ceftazidime (Fortum) 123
口服型第三代cephalosporins 125
第四代cephalosporins 128
Cefepime 133
Cefpirome 135
Carbapenems 137
Imipenem-cilastatin (Tienam) 139
Meropenem 141
Ertapenem 143
Aztreonam 145
β-lactams的副作用 147
Vancomycin 157
Teicoplanin 163
Fusidic acid 166
Linezolid 169
Daptomycin 173
Aminoglycosides 175
Quinolones的简介 190
Nalidic acid 198
第二代quinolones (fluoroquinolones) 201
Ciprofloxacin 206
Ofloxacin 209
Levofloxacin 211
第三代quinolones 215
Moxifloxacin 217
Germifloxacin 220
Macrolides 222
Erythromycin 224
Clarithromycin 227
Azithromycin 229
Telithromycin 233
Tetracyclines 236
Tigecycline 240
Colistin 243
Metronidazole 245
Clindamycin 248
Trimethoprim-sulfamethoxazole(TMP-SMX) 251
抗黴菌药物(antifungal agents) 254
Amphotericin B 255
Ketoconazole 262
Itraconazole 265
Posaconazole 268
Fluconazole 269
Voriconazole 273
Caspofungin 277
Micafungin 279
Anidulafungin 281
Terbinafine 282
Flucytosine [5-fluorocytosine (5-FC)] 284
抗结核药物(anti-TB agents) 286
Isoniazid (INAH) 293
Rifampin (RIF) 295
Pyrazinamide (PZA) 297
Ethambutol (EMB) 299
Streptomycin 302
Rifater (RFT) 304
Rifinah (RFN) 305
抗结核药物引起肝炎与治疗 306
抗病毒药物(antiviral agents) 309
Acyclovir 310
Valacyclovir 314
Famciclovir 316
Amantadine 318
Rimantadine 321
Neuraminidase inhibitors 323
Oseltamivir 325
Zanamivir 328
Inteeron (IFN) 330
Ribavirin 333
Lamivudine 336
Adefovir dipivoxil 338
Entecavir 339
第三部分:经验性抗生素 343
经验性抗生素的使用原则 343
社区性感染症(community-acquired infections) 346
Influenza 348
Acute group A streptococcal pharyngotonsillitis 350
Recurrent and chronic group A streptococcal pharyngotonsillitis 353
Acute otitis media (AOM) 354
Sinusitis 356
Dental infections 357
Deep neck infections 358
Community-acquired pneumonia (CAP) 359
Aspiration pneumonia 367
Lung abscess 369
Empyema 371
COPD with secondary infection 373
Bronchiectasis with secondary infection 374
Septic emboli 375
Impetigo 377
Erysipelas 378
Cellulitis 380
Periorbital cellulitis 382
Cutaneous abscess 383
Necrotizing fasciitis 384
Diabetic foot infections与pressure sores 387
Traumatic wound infections 389
Animal bites 390
VZV infections 392
Superficial fungal infections 394
Onychomycosis (tines unguium,灰指甲) 396
Scabies(疥疮) 398
Septic arthritis 401
Cystitis 403
Prostatitis 404
Acute pyelonephritis (APN) 406
UTI in pregnancy 410
Candidal UTI 413
Acute bacterial gastroenteritis 415
Pseudomembranous colitis 417
Helicobacter pylori infection 419
Spontaneous bacterial peritonitis (SBP) 422
Secondary peritonitis与intraabdominal abscess 426
Biliary tract infection (BTI) 429
Acute cholecystitis 431
Necrotizing pancreatitis并发续发性细菌感染 432
Liver abscess 434
Liver parenchymal infections 438
慢性B、C型肝炎 440
Bacterial meningitis 443
Sepsis 447
Staphylococcus aureus bacteremia 451
Coagulase(-)staphylococci (CoNS) bacteremia 452
Nonenterococcal bacteremia 454
Bacterial endocarditis 455
Salmonellosis 460
Rickettsial infections(包括Q fever) 462
Neonatal fever 464
Fever of unknown infectious source 466
Fever in travellers 468
Fabrile rash 470
Sexually transmitted diseases (STDs) 471
Syphilis 474
Pelvic inflammatory disease (PID)与Tubo-ovarian abscess 482
Infectious vaginitis 483
Anaerobic infections 485
Amebiasis 489
院内感染症(nosocomial infections) 493
Nosocomial UTI 494
Nosocomial pneumonia 497
Surgical wound infections 503
Nosocomial intraabdominal/pelvic infections 504
Catheter-related bacteremia 506
Nosocomial sepsis 509
A-V shunt infection 511
Candidemia 512
Neutropenic fever 514
第四部分:预防性抗生素 519
手术前预防性抗生素 519
接触后内科预防 530