1．Impact of Molecular Methods on Clinical Bacteriology&Robert C.George 1
2．Genomic DNA Digestion and Ribotyping&J.Zoe Jordens 17
3．Pulsed-Field Gel Electrophoresis&Mary Elizabeth Kaufmann 33
4．Plasmid Analysis&Alan P.Johnson and Neil Woodford 51
5．DNA Amplification:General Concepts and Methods&Nick A.Saunders and Jonathan P.Clewley 63
6．Arbitrarily Primed PCR Methods for Studying Bacterial Diseases&David Ralph and Michael McClelland 83
7．Genomic Fingerprinting by Application of rep-PCR&Anne M. Ridley 103
8．Molecular Approaches to the Identification of Streptococci&Robert E. McLaughlin and Joseph J.Ferretti 117
9．Pneumococcal Diseases&Anthony M. Smith and Keith P.Klugman 139
10．Molecular Approaches in Mycobacterium tuberculosis and Other Infections Caused by Mycobacterium Species&Madhu Goyal and Douglas B.Young 157
11．Diagnosis and Epidemiology of Diptheria&Androulla Efstratiou,Kathryn H. Engler,and Aruni de Zoysa 191
12．Diagnosis and Epidemiology of Infections Caused by Legionella spp.&Norman K. Fry and Timothy G.Harrison 213
13．Molecular Methods for Haemophilus influenzae&Mark A. Herbert,Derrick Crook,and E. Richard Moxon 243
14．The Impact of Molecular Techniques on the Study of Meningococcal Disease&Martin C. J. Maiden 265
15．Gonorrhea&Catherine A. Ison 293
16．Chancroid&Stephen A. Morse,David L. Trees,and Patricia A. Totten 309
17．Mycoplasma/Ureaplasma Infection&Claire B. Gilroy and David Taylor-Robinson 335
18．Application of Molecular Methods to the Study of Infections Caused by Salmonella spp.&E. John Threlfall,Mike D. Hampton,and Anne M. Ridley 355
19．Cholera&Timothy J. Barrett and Daniel N. Cameron 369
20．Diagnosis and Investigation of Diarrheagenic Escherichia coli&James P. Nataro and Juan Martinez 387
21．Campylobacter Infections:Species Identification and Typing&Janet R. Gibson and Robert J. Owen 407
22．Detection and Typing of Helicobacter pylori&Robert J. Owen and Janet R. Gibson 419
23．Nosocomial Infections Caused by Staphylococci Ariane Deplano and Marc J. Struelens 431
24．Application of Molecular Techniques to the Study of Nosocomial Infection Caused by Enterococci&Teresa M. Coque,Prema Seetulsingh,Kavindra V. Singh,and Barbara E. Murray 469
25．Molecular Approaches for the Detection and Identification of B-Lactamases&David J. Payne and Christopher J. Thomson 495
26．Biochemical and Enzyme Kinetic Applications for the Characte rization of B-Lactamases&David J. Payne and Tony H. Farmer 513
27．B-Lactam Resistance Mediated by Changes in Penicillin-Binding Proteins Christopher G. Dowson and Tracey J. Coffey 537
28．The Application of Molecular Techniques for the Study of Aminoglycoside Resistance&Karen J.Shaw,Frank J.Sabatelli,Linda Naples,Paul Mann,Roberta S. Hare,and George H. Miller 555
29．Molecular Investigation of Glycopeptide Resistance in Gram-Positive Bacteria&Neil Woodford and Jill M. Stigter 579
30．Quinolone Resistance&Janice C. Brown and Sebastian G.B. Amyes 617
31．Resistance to Tetracyclines,Macrolides,Trimethoprim,and Sulfonamides&Marilyn C. Roberts 641
Index 665