1 General Principles 1
Ⅰ．Pharmacokinetics:General Principles 1
Ⅱ．Pharmacokinetics:Administration and Absorption of Drugs 1
Ⅲ．Pharmacokinetics:Distribution of Drugs 4
Ⅳ．Pharmacokinetics:Metabolism of Drugs 5
Ⅴ．Pharmacokinetics:Elimination of Drugs and Drug Metabolites 6
Ⅵ．Pharmacodynamics 8
Ⅶ．Age-Dependent Pharmacology 11
Ⅷ．Regulations Governing the Development of New Drugs 12
2 Peripheral Neuropharmacology 14
Ⅰ．Overview of the Autonomic Nervous System 14
Ⅱ．Parasympathomimetics 17
Ⅲ．Cholinesterase Inhibitors 19
Ⅳ．Parasympathetic Blocking Drugs(Antimuscarinics) 20
Ⅴ．Ganglionic Blocking Drugs 21
Ⅵ．Neuromuscular Blocking Drugs 22
Ⅶ．Sympathomimetics 24
Ⅷ．α-Adrenoceptor Antagonists 26
Ⅸ．β-Adrenoceptor Antagonists 28
Ⅹ．Adrenergic Neuron-Blocking Drugs 29
Ⅺ．Drugs for Glaucoma 30
3 Central Neuropharmacology 31
Ⅰ．Principles of General Anesthesia 31
Ⅱ．Inhalation Anesthetics 32
Ⅲ．Intravenous Anesthetics 34
Ⅳ．Local Anesthetics 36
Ⅴ．Sedative-Hypnotic and Antianxiety Drugs 38
Ⅵ．Anticonvulsants 40
Ⅶ．Antipsychotic Drugs(Neuroleptics) 42
Ⅷ．Lithium Carbonate 43
Ⅸ．Antidepressants 44
Ⅹ．CNS Stimulants 46
Ⅺ．Drugs for Movement Disorders 47
Ⅻ．Drugs for Alzheimer's Disease 49
4 Substance Abuse and Pain 50
Ⅰ．General Features of Substance Abuse 50
Ⅱ．Sedative-Hypnotics 50
Ⅲ．Cigarettes 53
Ⅳ．CNS Stimulants 54
Ⅴ．Anabolic Steroids 54
Ⅵ．Hallucinogens 55
Ⅶ．Marijuana 55
Ⅷ．Gamma-Hydroxybutyric Acid(GHB) 56
Ⅸ．Opioids 56
Ⅹ．Narcotic Analgesics 57
Ⅺ．Analgesic Antipyretics 59
5 Cardiovascular Pharmacology 62
Ⅰ．Diuretics 62
Ⅱ．Calcium Channel Blockers 64
Ⅲ．Antihypertensives 65
Ⅳ．Drugs for Angina Pectoris 70
Ⅴ．Drugs for Congestive Heart Failure 72
Ⅵ．Antiarrhythmics 74
6 Pharmacology of Blood and Blood Vessels 80
Ⅰ．Anticoagulants 80
Ⅱ．Fibrinolytics 84
Ⅲ．Antiplatelet Drugs 84
Ⅳ．Antibleeding Drugs 86
Ⅴ．Drugs for Anemia 86
Ⅵ．Antihyperlipidemics 87
7 Autacoids, Drugs for Inflammatory and Gastrointestinal Disorders, and Vitamins 90
Ⅰ．Definition of Autacoids 90
Ⅱ．Histamine 90
Ⅲ．Histamine Blockers 90
Ⅳ．Antiasthmatic Drugs 91
Ⅴ．Eicosanoids 93
Ⅵ．Drugs for Migraine Headaches 95
Ⅶ．Drugs for Rheumatoid Arthritis 95
Ⅷ．Drugs for Gout 97
Ⅸ．Drugs for Acne 98
Ⅹ．Vitamins 98
Ⅺ．Drugs for Gastrointestinal Disorders 99
8 Endocrine Pharmacology 102
Ⅰ．Pituitary Hormones 102
Ⅱ．Adrenocortical Steroids 104
Ⅲ．Female Sex Hormones 106
Ⅳ．Fertility Drugs 108
Ⅴ．Male Sex Hormones 109
Ⅵ．Thyroid Hormones 109
Ⅶ．Calcium and Phosphate Metabolism 111
Ⅷ．Drugs for Diabetes Mellitus 113
Ⅸ．Drugs for Hypoglycemia 116
Ⅹ．Drugs for Obesity 117
9 Drugs for Bacterial Infections 118
Ⅰ．Principles of Bacterial Chemotherapy 118
Ⅱ．Cell Wall Inhibitors:Penicillins 119
Ⅲ．Cell Wall Inhibitors:Cephalosporins 123
Ⅳ．Cell Wall Inhibitors:Other β-Lactams 125
Ⅴ．Cell Wall Inhibitors:Non β-Lactams 125
Ⅵ．Protein Synthesis(30S Ribosome)Inhibitors:Aminoglycosides and Spectinomycin 126
Ⅶ．Protein Synthesis(30S Ribosome)Inhibitors:Tetracyclines 127
Ⅷ．Protein Synthesis(50S Ribosome)Inhibitors:Macrolides 128
Ⅸ．Other Protein Synthesis(50S Ribosome)Inhibitors 128
Ⅹ．DNA Gyrase Inhibitors:Quinolones 129
Ⅺ．Tetrahydrofolic Acid Synthesis Inhibitors 130
Ⅻ．Miscellaneous Antimicrobials 132
ⅩⅢ．Drugs for Mycobacterial Infections 132
10 Drugs for Infections from Eukaryotic Organisms and Viruses 134
Ⅰ．Antifungal Drugs 134
Ⅱ．Antiprotozoal Drugs 136
Ⅲ．Anthelmintics 137
Ⅳ．Antiviral Drugs 138
11 Cancer Chemotherapy 142
Ⅰ．Principles of Cancer Chemotherapy 142
Ⅱ．Anticancer Drugs 144
Ⅲ．Immunomodulators 149
12 Toxicology 152
Ⅰ．Emergency Toxicology 152
Ⅱ．Heavy Metal Toxicity and Chelators 154
Ⅲ．Other Toxic Substances 156
Index 159