The Physiology Of Induced HypothermiaPDF电子书下载

PART Ⅰ－GENERAL PHYSICOCHEMICAL AND PHYSIOLOGIC CONSIDERATIONS OF HYPOTHERMIA 1

Some Considerations of Physicochemical Factors in Hypothermia＆D．E．S．Brown 1

Effects of Hypothermia on General Metabolism＆S．M．Horvath and G．B．Spurr 8

The Effect of Low Temperatures upon Intracellular Potassium in Isolated Tissues＆I．M．Taylor 26

Potassium Exchange in Perfused Mammalian Skeletal Muscle＆E．M．Renkin 32

Electrolyte Transfer during Hypothermia＆Frank Gollan 37

Myocardial Balance of Potassium＆Henry Swan 42

Effects of Low Body Temperature on Tissue Oxygen Utilization＆E．F．Adolph 44

Oxygen Consumption of Mammalian Tissue at Reduced Temperatures＆F．A．Fuhrman 50

Respiratory Physiologic Studies During Hypothermia＆J．W．Severinghaus and M．Stupfei 52

The Gas Transport System in Hypothermia＆F．F．Kao 58

Hypothermia in the Unanesthetized Poikilothermic Dog＆A．D．Keller 61

Discussion：＆A．C．Burton，J．W．Severinghaus，and J．Cahn 78

Physiology of Hibernation in Mammals＆C．P．Lyman and P．O．Chat field 80

Discussion：＆A．C．Burton，A．D．Keller；E．Calkins，G．E．Burch，J．D．McMurrey，H．Swan，C．McC．Brooks，and R．K．Andjus 122

Resuscitation and Recovery of Hypothermic，Supercooled，and Frozen Mammals＆R．K．Andjus，J．E．Lovelock，and A．U．Smith 125

Discussion：＆F．J．Lewis，J．W．Severinghaus，W．Parkins，A．L．Hopkins，J．Fine，R．W．Brauer，F．D．Moore，R．D．Dripps，and J．Henley 143

PART Ⅱ－THE EFFECTS OF HYPOTHERMIA ON SPECIFIC SYSTEMS 146

Cardiovascular Functions in Deep Hypothermia＆H．E D＇Amato 146

Discussion：＆I．K．R．McMillan and E．Friedman 155

The Circulation During Rewarming＆Henry Swan 161

Discussion：＆R．O．Heimbecker and J．Fine 161

Coronary Blood Flow During Hypothermia＆R．M．Berne 165

The Effect of Hypothermia on Pituitary ACTH Release and on Adrenal Cortical and Medullary Secretion in the Dog＆D．M．Hume，R．H．Egdahl，and D．H．Nelson 170

Discussion：＆A D．Keller，M．E．De Bakey，J．R．Pappenheimer，and F．D．Moore 173

The Effect of Hypothermia on the Peripheral Serum Levels of Free 17-Hydroxycorticoids in the Dog，and in Man＆W．F．Bernhard 175

Discussion：＆J．Cahn and H．Swan 178

Some Problems of Hematology in Hypothermia：An Introduction＆William H．Crosby，Jr 183

The Effect of Hypothermia on Platelets and White Cells in Dogs＆T．J．Villalobos，E．Adelson，and P．A．Riley 186

Discussion：＆C．M．Couves，D．Warren，J．E．Rhoads，J．A．Helmsworth，and J．Adams-Ray 194

Renal Functional Response to Hypothermia and Ischemia in Man and Dog＆J．H．Moyer，G．C．Morris，and M．E．De Bakey 199

Effect of Hypothermia on the Kidney＆R．K．Andjus 214

Discussion：＆P．A．Riley 218

Hypothermia and Temporary Occlusion of the Hepatic Circulation＆N．E．Shumway and F．J．Lewis 221

Effect of Hypothermia on Metabolism and Drug Detoxification in the Isolated Perfused Rabbit Liver＆I．Gray，R．R．Rueckert，and R．R．Rink 226

The Effect of Hypothermia on the Isolated Perfused Rat Liver＆R．W．Brauer 235

Effects of Cold on the Nervous System＆I．D．McQueen 243

Effects of Changes in Arterial pCO2 on Cerebral Blood Flow and Metabolism during Hypothermia＆I．Kleinerman 251

Hypothermia and the Central Nervous System＆H．L．Rosomoff 253

Hypothermia and the Nervous System＆C．McC．Brooks 260

Experimental and Clinical Observations on the Use of Hypothermia to Prevent Ischemic Damage to the Central Nervous System＆R．G．Pontius and M．E．De Bakey 264

Discussion：＆W．H．Lougheed 270

Possibilities and Limitations of Differential Brain Cooling in Dogs＆J．M．Jensen，W．M．Parkins，and H．M．Vars 271

Discussion：＆W．M．Parkins，J．Cahn，and J．D．McMurrey 274

REVIEW AND APPRAISAL OF PARTS Ⅰ AND Ⅱ＆J．W．Severinghaus 279

REVIEW AND APPRAISAL OF PARTS Ⅰ AND Ⅱ＆S．M．Horvath 284

PART Ⅲ－MYOCARDIAL IRRITABILITY AND HYPOTHERMIA 287

Hypothermia and the Physiology of Cardiac Excitability＆C．McC．Brooks 287

Temperature Effects on Cardiac Transmembrane Potentials＆B．F．Hoflman 302

Discussion：＆G．E．Burch，J．W．Severinghaus．and D．Durrer 324

Myocardial Irritability in Experimental Immersion Hypothermia＆A．H．Hegnauer and B．G．Covino 327

Discussion：＆F．J．Lewis，B．F．Hoffman，F．Gollan，A．Riberi，and J．Cahn 340

REVIEW AND APPRAISAL OF PART Ⅲ－C．McC．Brooks and B．F．Hoffman 355

PART Ⅳ－CLINICAL APPLICATION OF INDUCED HYPOTHERMIA 363

Hypothermia in Neurosurgery＆E．H．Botterell and W．M．Lougheed 363

Discussion：＆G．H．Clowes，Jr．，W．M．Lougheed，and E．H．Botterell 368

Effect of Hypothermia on Tolerance to Hemorrhagic Shock＆E．W．Friedman，D．Davidoff，and Jacob Fine 369

Discussion：＆E．Frank 378

Experimental Observations on the Influence of Hypothermia and Autonomic Blocking Agents on Hemorrhagic Shock＆R．C．Overton and M．E．De Bakey 381

Hypothermia and Experimental Myocardial Infarction＆Charles Huggim 392

Treatment of the Seriously Ill，Febrile Patient with Surface Cooling＆F．J．Lewis，D．M．Ring，and J．F．Alden 394

Discussion：＆W．J．Kolff，E．Calkins，H．Swan，F．J．Lewis，J．Henley，and C．W．Hughes 399

The Use of Hypothermia in Cardiac Surgery＆Henry Swan 402

Discussion：＆F．J．Lewis，J．H．Kay，I．K．R．McMillan，W．P．Longmire，Jr．，J．Cahn，C．W．Hughes，and H．Swan 409

REVIEW AND APPRAISAL OF PART Ⅳ＆R．D．Dripps 413

PART Ⅴ－TECHNIQUES OF INDUCING HYPOTHERMIA 415

Problems in Methods of Inducing Hypothermia by Use of External Cooling＆W．H．Muller，Jr．and J．F．Dammann 415

Problems in Methods of Inducing Hypothermia by Use of Drugs and Internal Cooling＆J．F．Dammann and W．H．Muller，Jr 422

Discussion：＆J．Adams-Ray，A．Riberi，R．O．Heimbecker，F．Gollan，R．W．Brauer，and L．I．Goldberg 430

REVIEW AND APPRAISAL OF PART Ⅴ＆R．D．Dripps 439

Attendance 441

Index of Authors and Discussants 447