CHAPTER 1．GROWTH AND DEVELOPMENT 1
Normal Growth and Development 1
Disturbances of Physical Growth 4
Mongolism 9
CHAPTER 2．THE NEWBORN 12
General Classification 12
Postmortem Examination 14
Anatomic Changes Peculiar to Newborn Period 16
Infections in Newborn Period 21
Antenatal Infections 21
Specific Lesions of Other Organs 27
Lesions of Unknown Etiology or Significance 28
CHAPTER 3．PREMATURITY AND POSTMATURITY 34
Definitions 34
Prematurity 35
Postmaturity 43
The Giant Fetus 45
CHAPTER 4．DISEASES OF THE PLACENTA 48
Abnormalities of Attachment，Separation and Position 48
Abnormalities of Form 49
Tumors 49
Specific Lesions 50
CHAPTER 5．ERYTHROBLASTOSIS FETALIS 52
Etiology of Erythroblastosis Fetalis 52
Pathogenesis of Erythroblastosis Fetalis 54
Kernicterus 56
CHAPTER 6．CONGENITAL MALFORMATIONS 60
General Data 60
Experimental Teratology 64
CHAPTER 7．INBORN ERRORS OF METABOLISM 71
Terminology 71
Errors in Protein Metabolism 71
Errors in Carbohydrate Metabolism 73
Errors in Lipid Metabolism 76
Errors in Pigment Metabolism 82
Metabolic Diseases of Unknown Mechanisms 83
CHAPTER 8．NUTRITIONAL DISEASES 91
General Data 91
Malnutrition and Starvation 91
Obesity 91
Vitamin Deficiencies 92
Deficiencies of Other Substances 108
Multiple and Combined Nutritional Deficiencies or Both 110
CHAPTER 9．DISEASES RELATED TO HYPERSENSITIVITY 114
General Data 114
Description of Specific Diseases 114
CHAPTER 10．DISEASES CAUSED BY POISONS 123
General Data 123
Corrosives 123
Gaseous Poisons 124
Metallic Poisons 125
Organic Compounds 128
CHAPTER 11．SUDDEN AND UNEXPECTED DEATH IN INFANCY 133
Description and Possible Causes 133
CHAPTER 12．TUMORS 136
An Hypothesis on the Nature of Tumors 136
Tumors of Childhood 139
CHAPTER 13．DISEASES CAUSED BY BACTERIA 147
General Data 147
General Bacterial Diseases 148
Specific Bacterial Diseases 154
Tuberculosis 169
Leprosy 180
CHAPTER 14．DISEASES CAUSED BY SPIROCHETES 185
General Description 185
Specific Diseases 185
CHAPTER 15．DISEASES CAUSED BY RICKETTSIA AND OTHER ORGANISMS 204
Diseases caused by Rickettsia 204
Miscellaneous Infections 207
CHAPTER 16．DISEASES CAUSED BY VIRUSES 210
Introduction 210
General Characteristics of Lesions Caused by Viruses 210
Immunity to Viral Diseases 211
Specific Viral Diseases 213
CHAPTER 17．DISEASES CAUSED BY FUNGI 247
Concept of Pathogenicity 247
General Pathologic Anatomy of Mycotic Lesions 248
Specific Fungus Diseases 250
CHAPTER 18．DISEASES CAUSED BY PROTOZOA 259
General Description 259
Specific Diseases 259
CHAPTER 19．DISEASES CAUSED BY WORMS AND ARTHROPODS 276
General Data 276
Nematode Infestations 276
Platyhelminth Infestations 283
Tick Paralysis 291
CHAPTER 20．DISEASES OF THE CENTRAL NERVOUS SYSTEM 292
General Data 292
Development of Central Nervous System 296
Congenital Malformations of Brain 297
Congenital Malformations of Spinal Cord 303
Other Congenital Anomalies and Diseases 304
Infantile Cerebral Palsy 308
Hydrocephalus 309
Cerebral Injury at Birth 312
Hereditary Degenerative Diseases 312
Nonhereditary Degenerative Diseases of Spinal Cord 326
Vascular Lesions of Central Nervous System 328
Inflammations of Nervous System 329
Neoplasms of Central Nervous System 333
CHAPTER 21．TUMORS OF THE PERIPHERAL NERVOUS SYSTEM 347
Malignant and Benign Tumors 347
CHAPTER 22．DISEASES OF THE SPECIFIC SENSORY ORGANS 353
Diseases of Eye and Adnexa 353
Diseases of Ear 358
Diseases of Nose 359
Diseases of Lips 361
Diseases of Mouth and Tongue 362
Diseases of Teeth 364
Diseases of Jaws 369
Diseases of Salivary Glands 369
Diseases of Pharynx 370
CHAPTER 23．DISEASES OF THE RESPIRATORY SYSTEM 374
General Data 374
Congenital Anomalies of Lung 374
Congenital Anomalies of Trachea and Larynx 379
Pulmonary Lesions Associated with Circulatory Disorders 380
Lesions of Pulmonary Vessels 381
Lesions Associated With Interference of Pulmonary Ventilation 382
Infectious Diseases of Respiratory System 384
Miscellaneous Diseases of Lung 391
Tumors of Respiratory System 393
Diseases of Pleura and Thoracic Cavity 395
Diseases of Mediastinum 395
Diseases of Diaphragm and Chest Wall 396
CHAPTER 24．DISEASES OF THE HEART AND BLOOD VESSELS 399
General Data 399
Congenital Heart Diseases 399
Infectious Diseases of Heart 413
Diseases of Coronary Arteries 414
Rheumatic Fever 415
Nonspecific Degenerative Lesions of Heart 422
Peculiarities of Fetal and Newborn Heart 422
Tumors of Heart 423
Diseases of Blood Vessels 424
Tumors of the Blood Vessels 425
CHAPTER 25．DISEASES OF THE BLOOD 430
General Data 430
Generic Classification of Diseases of Blood 431
Congenital Anomalies of Blood 432
Infectious Diseases of Blood 438
Effect of Nutritional Deficiencies on Blood 439
Disorders of Blood Associated with Toxic or Unknown Agents 440
Diseases of Blood Related to Hypersensitivity 443
Neoplastic Diseases of Blood 444
CHAPTER 26．DISEASES OF THE SPLEEN AND LYMPH NODES 449
General Data 449
Diseases of Spleen 449
Diseases of Lymph Nodes 451
CHAPTER 27．DISEASES OF THE GASTROINTESTINAL TRACT 460
General Data 460
Embryologic Development 460
Diseases of Esophagus 462
Diseases of Stomach 465
Diseases of Small Intestines 467
Diseases of Colon 473
Diseases of Peritoneum，Mesentery，and Abdominal Walls 477
Malformations of Anus and Rectum 480
Appendicitis 480
CHAPTER 28．DISEASES OF THE LIVER 484
General Comparative Data 484
Embryology 484
Jaundice 486
Congenital Anomalies of Liver 487
Degenerations of Liver 488
Necrosis of Liver 489
Infections of Liver 490
Miscellaneous Diseases of Liver 496
Infantile and Juvenile Cirrhosis 496
Tumors of Liver 497
CHAPTER 29．DISEASES OF THE EXTRAHEPATIC BILIARY SYSTEM 502
Structure of Gallbladder and Biliary Ducts 502
Congenital Malformations of Biliary System 502
Acquired Diseases of Biliary System 508
Tumors of Biliary System 508
CHAPTER 30．DISEASES OF THE PANCREAS 510
Congenital Anomalies of Pancreas 510
Acquired Diseases of Pancreas 510
Pancreatic Lesions in Chronic Renal Disease 511
Cysts of Pancreas 512
Tumors of Pancreas 512
CHAPTER 31．DISEASES OF THE GENITOURINARY SYSTEM 513
Statistical Significance 513
Embryology 513
Postnatal Histologic Development 517
Congenital Anomalies of Genitourinary System 517
Acquired Diseases of Kidney 526
Diseases of Lower Genitourinary Tract 537
Precocious Puberty 546
CHAPTER 32．DISEASES OF THE ENDOCRINE GLANDS 549
General Data 549
The Pituitary Gland 549
The Pineal Gland 554
The Thyroid Gland 555
The Parathyroids 563
The Adrenal Glands 565
The Paraganglia 571
The Thymus 572
CHAPTER 33．DISEASES OF THE BONES AND JOINTS 578
Mode of Classification 578
Congenital Absence of Bones or Parts of Bones 578
Hypoplasia of Bones 579
Hyperplasia of Bones 579
Alterations in Chondromatous Element of Bone 581
Deficient Osteoblastic Formation of Bone 585
Destructive Lesions of Bone 586
Neoplastic Lesions of Bone 592
Other Tumors of Bone 600
Diseases of Joints 601
CHAPTER 34．DISEASES OF THE MUSCLES AND SUPPORTING TISSUES 607
General and Technical Data 607
Congenital Abnormalities 607
Muscular Dystrophies 608
Neural Lesions 610
Diseases of Nervous System with Outstanding Effects on the Muscular Apparatus 611
Diseases of Muscle of Unknown Etiology 612
Effects of Generalized Disease on Striated Muscle 613
Tumors of Muscle 614
Tumors of Fibrous Tissue and Tendon 614
Diseases of Tendon 618
CHAPTER 35．DISEASES OF THE SKIN 620
General Description 620
Embryology of Skin 620
Congenital Anomalies of Skin 621
Infectious Inflammatory Diseases 627
Noninfectious Inflammatory Diseases 629
Tumors of Skin 637
Tumors of Adnexal Structures 642
APPENDIX 649
INDEX 661