a symposium on the chemical basis of heredityPDF电子书下载
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Ⅰ.CELLULAR UNITS OF HEREDITY 1
The Role of the Nucleus in HeredityGeorge WBeadle 3
Chromosome StructureHans Ris 23
Discussion 62
The Elementary Units of HereditySeymour Benzer 70
Crossing Over and Gene Conversion in NeurosporaHerschel KMitchell 94
Gene Conversion and Problems of AllelismPatricia StLaurence and David MBonner 114
Gene Function and Enzyme FormationSigmund RSuskind 123
Discussion 129
The Role of the Cytoplasm in HeredityDavid LNanney 134
Discussion 164
Ⅱ.ROLE OF THE NUCLEUSNUCLEIC ACIDS AND ASSOCIATED STRUCTURES IN CELL DIVISION AND PROTEIN SYNTHESIS 167
Some Problems in the Chemistry of MitosisDaniel Mazia 169
Some Cytochemical Contributions to Genetic ChemistryMax Alfert 186
Discussion 194
The Nucleus and Protein SynthesisVAllfrey,AEMirsky and SOsawa 200
Nucleic Acids and the Synthesis of ProteinsSSpiegelman 232
Effects of Nucleotides on the Incorporation of Amino Acids into ProteinGeorge CWebster 268
Repression and Induction as Control Mechanisms of Enzyme Biogenesis:TheAdaptiveFormation of AcetylornithinaseHenry JVogel 276
Discussion 290
Ⅲ.NUCLEIC ACIDS AS TRANSFORMING AGENTS 297
X-Ray Inactivation Studies on Solutions of Transforming DNA of PneumococcusHarriett Ephrussi-Taylor 299
Criteria for Quantitative Genetic Transformation of BacteriaRollin DHotchkiss 321
Studies on Transformation of Hemophilus InfluenzaeSol HGoodgal and Roger MHerriott 336
Photoreactivation of Hemophilus Influenzae Transforming Factor for Streptomycin Resistance by an Extract of Escherichia Coli BSol HGoodgalClaud SRupert and Roger MHerriott 341
Discussion 343
Properties of the Transforming PrinciplesStephen Zamenhof 351
Chromatographic Fractionation of EColi DNA Containing 5-Bromouracil-2-C14Aaron Bendich,Herbert BPahl and George Bosworth Brown 378
Discussion 386
Ⅳ.VIRUSES AS BEARERS OF HERITABLE CHARACTERISTICS 397
The Virulent Teven Phages of Escherichia Coli BRoger MHerriott 399
Transduction:A Comparative ReviewPhilip EHartman 408
Discussion 463
Genetic Aspects of LysogenyFrancois Jacob and Elie LWollman 468
Discussion 499
The Nature of the Progeny of Virus Reconstituted from Protein and Nucleic Acid of Different Strains of Tobacco Mosaic VirusHFraenkel-Conrat,Beatrice ASinger and Robley CWilliams 501
Discussion 512
Ⅴ.NUCLEIC ACIDS—CHEMICAL COMPOSITION AND STRUCTURE 519
Base Composition of Deoxypentose and Pentose Nucleic Acids in Various SpeciesErwin Chargaff 521
Discussion 527
The Structure of DNAFHCCrick 532
The Physical Heterogeneity of DNAJAVButler and KVShooter 540
Discussion 543
X-Ray Studies on RNA and the Synthetic PolyribonucleotidesJDWatson 552
The Structure of Synthetic Polyribonucleotides and the Spontaneous Formation of a New Two-Stranded Helical MoleculeAlexander Rich 557
Discussion 562
Importance of Helices in Molecules of Biological OriginBarbara WLow 565
Discussion 575
Ⅵ.SYNTHESIS OF NUCLEOTIDES AND NUCLEIC ACIDS 577
Pathways of Enzymatic Synthesis of Nucleotides and PolynucleotidesArthur Kornberg 579
The Enzymatic Conversion of Deoxyuridylic Acid to Thymidylic Acid and the Participation of Tetrahydrofolic AcidMorris Friedkin and Arthur Kornberg 609
Polynucleotide SynthesisSevero Ochoa and Leon AHeppel 615
The Nature of RNA Labeling in HomogenatesVan RPotter,John HSchneider and Liselotte IHecht 639
Discussion 644
The Biosynthesis of Nucleic Acids in Sonic Microbial SystemsSeymour SCohen 651
RNA Metabolism in T2-Infected Escherichia ColiElliot Volkin and LAstrachan 686
Discussion 695
Ⅶ.MECHANISM OF DUPLICATION 697
On the Mechanism of DNA ReplicationMax Delbruck and Gunther SStent 699
The Molecular Basis of Genetic Recombination in PhageCLevinthal and CAThomasJr 737
Discussion 743
Ⅷ.SUMMARYBentley Glass 757
AUTHOR INDEX OF PARTICIPANTS 837
SUBJECT INDEX 839