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Introduction＆R．LEE CLARK 1

STRUCTURE OF VIRUSES 5

A Comparative Study of the Structures of a Variety of Bacteriophage Particles with Some Observations on the Mechanism of Nucleic Acid Injection＆DESMOND KAY 7

Structure and Assembly of Regular Virus Particles＆D．L．D．CASPAR and A．KLUG 27

Electron Microscope Studies on the Structure and Symmetry of Virus Particles＆R．W．HORNE 40

Icosahedral Viruses—A Geometric Approach to Their Maturation＆HEATHER DONALD MAYOR 63

Morphology of the RNA Phage FH5＆J．HUPPERT，ANTOINETTE RYTER，and JEANNE FOUACE 68

The Arthropod Viruses＆KENNETH M．SMITH 72

Studies on the Structure of the Mammary Tumor-Inducing Virus(Bittner)and of Leukemia Virus(Gross)＆L．DMOCHOWSKI，C．E．GREY，F．PADGETT，and J．A．SYKES 85

Structure and Genetic Properties of Bacterial Viruses＆THOMAS F．ANDERSON 122

Virus Particles of Mouse Lymphomas and Mammary Carcinoma＆R．KINOSITA and T．KAKEFUDA 141

REPLICATION OF VIRUSES：BIOCHEMISTRY OF VIRUS-INFECTED CELLS 149

Influence of Phages on the Synthesis of Host Enzymes of Bacteria＆MICHAEL B．YARMOLINSKY 151

The Functions of the RNA of Bacteriophage f2＆NORTON D．ZINDER 173

Substances Produced During Replication of Plant Viruses＆ROY MARKHAM 180

Biosynthesis of Viral Ribonucleic Acids＆M．HOMMA，A．V．RAKE，W．PARANCHYCH，D．B．ELLIS，and A．F．GRAHAM 191

The Programing of Herpes Virus Multiplication in Mammalian Cells＆BERNARD ROIZMAN 205

Studies of Replication and Properties of the Bittner Virus＆DAN H．MOORE and MICHAEL J．LYONS 224

VIRAL NUCLEIC ACID：PROPERTIES AND MODE OF REPLICATION 243

Viral Nucleic Acid：Properties and Mode of Replication．Introduction＆W．M．STANLEY 245

Replication of the Nucleic Acids of the Bacterial Viruses＆ROBERT L．SINSHEIMER 246

Biosynthesis of Infectious Ribonucleic Acid of Tobacco Mosaic Virus by Extracts of Healthy Plants＆GEORGE W．COCHRAN 252

Properties of the DNA of Polyoma Virus＆RENATO DULBECCO 271

Early Events in the Reproduction Cycle of Animal Viruses＆P．HAUSEN，H．HAUSEN，R．ROTT，C．SCHOLTISSEK，and W．SCH？FER 282

Early Changes Following Virus Infection：Thymidine Kinase Induction in Cells Infected with Vaccinia and Herpes Simplex Viruses＆SAUL KIT 296

Changes in RNA and Protein Synthesis in Mammalian Cells Infected with a Virulent Virus＆RICHARD M．FRANKLIN and DAVID BALTIMORE 310

AVIAN VIRUSES AND NEOPLASIA 327

Avian Viruses and Neoplasia：Introduction＆W．R．BRYAN 329

Biological and Structural Properties of Rous Sarcoma Viruses＆R．J．C．HARRIS 331

Studies on the Biological，Biochemical，and Biophysical Properties of Avian Tumor Viruses＆J．W．BEARD，R．A．BONAR，URSULA HEINE，GUY DE THé，and DOROTHY BEARD 344

The Infection of Chicken Fibroblast Cultures by Avian Myeloblastosis Virus＆PETER K．VOGT 374

Induction of Differentiation in Certain Target Cells by Avian Myeloblastosis Virus：An In Vitro Study＆M．A．BALUDA，I．E．GOETZ，and S．OHNO 387

BERTNER FOUNDATION LECTURE 401

Properties of a Virus Isolated from Leukemic Mice，Inducing Various Forms of Leukemia and Lymphomas in Mice and Rats＆LUDWIK GROSS 403

VIRUSES AND INTERFERON 427

Viruses and Interferon：Introduction＆W．HENLE 429

Interference and Cell Division＆KURT PAUCKER 430

The Effect of Interferon on the Synthesis of Viral Nucleic Acid＆ROYCE Z．LOCKART，JR．，and T．SREEVALSAN 447

Interference and Interferon in Relation to Tumor Viruses and Tumor Cells＆A．C．ALLISON 462

BIOLOGICAL ASPECTS OF TUMOR INDUCTION BY VIRUSES 485

The Interaction of Polyoma Virus with Hamster Fibroblasts＆MICHAEL STOKER 487

The Role of the Mammary Tumor Virus in Mouse Mammary Noduligenesis and Tumorigenesis＆K．B．DEOME 498

Significance of the Absence of Infectious Virus in Virus-Induced Tumors＆H．RUBIN and H．HANAFUSA 508

INTERRELATIONSHIP OF VIRUSES：INTRACELLULAR AND EXTRACELLULAR FACTORS IN NEOPLASIA 527

The Possible Role of a＂Transmissible Factor＂in Leukemia Induction by Radiation Plus Urethan＆I．BERENBLUM 529

The Combined Action of Viruses and Other Carcinogens＆M．H．SALAMAN，K．E．K．ROWSON，F．J．C．ROE，J．K．BALL，J．J．HARVEY，and G．DE BENEDICTIS 544

Studies on the Oncogenicity of Human Adenovirus＆JOHN J．TRENTIN，YOSHIRO YABE，and GRANT TAYLOR 559

Observations on a Specific Adenovirus 12 Antigen in Virus-Free Adenovirus Tumor Transplants＆R．J．HUEBNER，W．P．ROWE，and L．D．BERMAN 564

Lymphoma in ICR Mice Treated with 4-Nitroquinoline N-Oxide (4-NQO)＆R．KINOSITA and T．TANAKA 571

＂Newer＂and＂Older＂Viruses in Mammalian Malignancy＆MAURICE R．HILLEMAN 580

A Children＇s Cancer Dependent on Environment＆DENIS BURKITT 615

The Role of Viruses in Relation to Cancer in Animals and Man＆FRANK L．HORSFALL，JR． 630

Index 643