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PART ONE CLINICAL 1

ADRENALECTOMY IN CANCER OF THE BREAST＆SIR STANFORD CADE 2

ADRENALECTOMY IN CANCER OF THE BREAST＆J．HELLSTROM and C．FRANKSSON 5

THE RESULTS OF ADRENALECTOMY WITH GONADECTOMY IN BREAST CANCER＆L．N．PYRAH 22

DISCUSSION AFTER＇ADRENALECTOMY IN BREAST CANCER＇ 25

HYPOPHYSECTOMY IN THE MANAGEMENT OF METASTATIC CARCINOMA OF THE BREAST＆ROLF LUFT，HERBERT OLIVECRONA，DENIS IKKOS，LARS BERTIL NILSSON and HARRY MOSSBERG 27

SURGICAL HYPOPHYSECTOMY IN THE TREATMENT OF ADVANCED CANCER OF THE BREAST＆BRONSON S．RAY and OLOF H．PEARSON 36

DISCUSSION AFTER＇SURGICAL HYPOPHYSECTOMY IN BREAST CANCER＇ 45

TREATMENT OF ADVANCED BREAST CANCER BY YTTRIUM-90 IMPLANTATION OF THE PITUITARY＆A．P．M．FORREST，D．W．BLAIR，S．R．MORRIS，D．A．PEEBLES BROWN，A．T．SANDISON，J．S．VALENTINE and C．F．W．ILLINGWORTH 46

PITUITARY ABLATION AND THE VISUAL FIELDS＆R．W．HARRINGTON 54

RADIOACTIVE GOLD IMPLANTATION OF THE PITUITARY IN THE TREATMENT OF BREAST CANCER＆K．H．BAUER and L．A．SCHWEITZER 56

CHANGES OF PITUITARY FUNCTION FOLLOWING ISOTOPE(32P)INJECTION AND PITUITARY STALK SECTION＆P．H．BUXTON，F．L．DAVIES，A．M．JELLIFFE，K．M．JONES，V．LOGUE，J．D．N．NABARRO and G．WALKER 58

DISCUSSION AFTER＇OTHER METHODS OF PITUITARY ABLATION＇ 67

COMPARISONS AND RESULTS OF ADRENALECTOMY AND HYPOPHYSECTOMY＆H．J．B．ATKINS 69

DISCUSSION AFTER＇COMPARISON OF ADRENALECTOMY AND HYPOPHYSECTOMY＇ 76

TUMOUR AUTONOMY IN CARCINOMA OF THE BREAST：THE PROBLEM OF RECOGNITION OF THE HORMONESTIMULATED TUMOUR＆ANDREW G．JESSIMAN 77

DISCUSSION AFTER＇TUMOUR AUTONOMY AND THE HORMONE-STIMULATED TUMOUR＇ 88

PHYSIOLOGICAL EFFECTS OF ADRENALECTOMY AND HYPOPHYSECTOMY＆OLOF H．PEARSON and BRONSON S．RAY 90

METABOLIC EFFECTS OF HYPOPHYSECTOMY AND OF IMPLANTATION OF RADIOACTIVE GOLD AND YTTRIUM IN THE PITUITARY＆F．T．G．PRUNTY 95

REACTIONS FOLLOWING BILATERAL ADRENALECTOMY＆C．FRANKSSON 98

DISCUSSION AFTER＇PHYSIOLOGICAL EFFECTS OF ADRENALECTOMY AND HYPOPHYSECTOMY＇ 100

CLINICAL-DISCUSSION AND SUMMARY＆C．F．W．ILLINGWORTH 101

PART TWO PATHOLOGY 105

ON THE PHARYNGEAL HYPOPHYSIS＆W．MULER 106

HISTOLOGICAL AND CHEMICAL STUDIES ON ADRENAL GLANDS FROM PATIENTS WITH BREAST CARCINOMA＆T．SYMINGTON，J．GRANT，V．J．O＇DONNELL，I．A．CARR and A．P．M．FORREST 111

HISTO-HORMONAL STUDIES ON THE HUMAN ANTERIOR HYPOPHYSIS AND THE IMMUNOCHEMISTRY OF ITS HORMONES＆A．R．CURRIE，B．CRUICKSHANK，C．L．HEWETT and J．B．DEKANSKI 122

A POSTMORTEM SURVEY OF THE ADULT BREAST WITH SOME OBSERVATIONS ON GONAD AND PITUITARY＆A．T．SANDISON 128

ALTERATIONS IN THE MICROANATOMY OF THE BREAST AS A RESULT OF CHANGES IN THE HORMONAL ENVIRONMENT＆J．L．HAYWARD and A．G．PARKS 133

PATHOLOGY-DISCUSSION AND SUMMARY＆T．SYMINGTON and A．R．CURRIE 135

PART THREE HORMONE STUDIES 139

CHEMICAL NAMES-TRIVIAL AND PROPER 140

THE PLACE OF HORMONE ASSAY IN HUMAN BREAST CANCER＆J．A．STRONG 141

ANTERIOR PITUITARY HORMONES AND MAMMOTROPHINS 157

THE ESTIMATION OF ANTERIOR PITUITARY HORMONES IN PATIENTS WITH MAMMARY CARCINOMA＆J．A．LORAINE 158

THE EFFECT OF IRRADIATION OF THE PITUITARY ON GONADOTROPHIN EXCRETION IN WOMEN WITH ADVANCED MAMMARY CANCER＆E．BOYLAND，B．GODSMARK，W．P．GREENING，P．RIGBY-JONES，J．J．STEVENSON and in part M．A．M．ABUL-FADL 170

URINARY GONADOTROPHINS＆A．C．CROOKE 173

MAMMOTROPHIC POTENCY IN HUMAN URINE＆GEOFFREY HADFIELD 174

OBSERVATIONS ON THE RESPONSE OF MAMMARY GLANDS OF MICE TO PROLACTIN＆R．E．WILLIAMS 175

ANTERIOR PITUITARY HORMONES AND MAMMOTROPHINS-DISCUSSION AND SUMMARY＆J．A．LORAINE 179

URINARY OESTROGENS 180

PARALLEL CHEMICAL AND BIOLOGICAL ASSAYS OF URINARY OESTROGENS AFTER ADRENALECTOMY AND HYPOPHYSECTOMY＆R．D．BULBROOK，F．C．GREENWOOD and P．C．WILLIAMS 181

REMARKS ON THE NATURE OF KOBER CHROMOGENS EXCRETED BY SOME OOPHORECTOMIZED-ADRENALECTOMIZED PATIENTS＆E．DICZFALUSY，G．BIRKE，C．FRANKSSON，J．HELLSTROM，S．HULTBERG，L．-O．PLANTIN and A．WESTMAN 186

A COMPARISON OF METHODS FOR THE ANALYSIS OF OESTRONE，OESTRADIOL AND OESTRIOL IN EXTRACTS OF HUMAN URINE＆T．F．GALLAGHER，S．KRAYCHY，JACK FISHMAN，J．B．BROWN and GUY F．MARRIAN 196

URINARY OESTROGEN EXCRETION IN THE STUDY OF MAMMARY CANCER＆J．B．BROWN 197

OESTROGEN EXCRETION AFTER HYPOPHYSECTOMY IN BREAST CANCER＆E．F．SCOWEN 208

ON THE CORRELATION BETWEEN STEROID EXCRETION AND CLINICAL RESPONSE TO OOPHORECTOMY PLUS ADRENALECTOMY IN BREAST CANCER＆G．BIRKE，E．DICZFALUSY，C．FRANKSSON，J．HELLSTROM，S．HULTBERG，L．-O．PLANTIN and A．WESTMAN 213

URINARY OESTROGENS-DISCUSSION AND SUMMARY＆G．F．MARRIAN 221

URINARY 17-OXOSTEROIDS 223

THE EFFECT OF HYPOPHYSECTOMY ON THE URINARY EXCRETION OF 17-OXOSTEROIDS＆MARJORIE E．HOLLIDAY，A．E．KELLIE and A．P．WADE 224

URINARY 17-OXOSTEROID EXCRETION AFTER SURGERY FOR BREAST CANCER＆R．HOBKIRK 239

ON THE EXCRETION PATTERN OF 17-OXOSTEROIDS AND CORTICOSTEROIDS IN BREAST CANCER＆L．-O．PLANTIN，G．BIRKE，E．DICZFALUSY，C．FRANKSSON J．HELLSTROM，S．HULTBERG and A．WESTMAN 244

THE EXCRETION OF 17-OXOSTEROIDS IN THE URINE OF PATIENTS WITH GENERALIZED CARCINOMATOSIS SECONDARY TO CARCINOMA OF THE BREAST＆BETTY J．ALLEN，J．L．HAYWARD and W．H．H．MERIVALE 253

URINARY 17-OXOSTEROIDS-DISCUSSION AND SUMMARY＆G．F．MARRIAN 263

PART FOUR EXPERIMENTAL PATHOLOGY 265

ENDOCRINE ASPECTS OF MAMMARY GROWTH AND FUNCTION，PARTICULARLY IN RELATION TO PITUITARY HORMONES＆A．T．COWIE and S．J．FOLLEY 266

EXPERIMENTAL OBSERVATIONS ON MAMMOTROPES AND THE MAMMARY GLAND＆JACOB FURTH and KELLY H．CLIFTON 276

ON HORMONE DEPENDENCE IN THE TRANSMISSION OF MAMMARY TUMOUR AGENT FROM MALES＆L．SEVERI，C．BIANCIFIORI，M．OLIVI and F．SQUARTINI 283

STUDIES ON THE HORMONE DEPENDENCE OF EXPERIMENTAL BREAST TUMOURS IN MICE＆O．MUHLBOCK 291

HORMONE-DEPENDENT TUMOURS IN MICE＆B．D．PULLINGER 296

HORMONAL PROMOTION AND RESTRAINT OF GROWTH OF EXPERIMENTAL MAMMARY TUMOURS＆CHARLES HUGGINS and KLAUS MAINZER 297

HORMONAL MECHANISMS IN MAMMARY CARCINOGENESIS＆J．W．JULL 305

HORMONE RESPONSIVENESS OF MAMMARY TUMOURS＆L．FOULDS 318

SPLENIC ENLARGEMENT IN ASSOCIATION WITH MAMMARY TUMOURS IN MICE＆W．REID 321

EXPERIMENTAL PATHOLOGY-DISCUSSION AND SUMMARY＆P．R．PEACOCK 323

REVIEW OF THE CONFERENCE 325

REVIEW OF THE CONFERENCE＆C．F．W．ILLINGWORTH 326