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AN INTRODUCTION TO GENETIC ANALYSIS  SECOND EDITION
AN INTRODUCTION TO GENETIC ANALYSIS  SECOND EDITION

AN INTRODUCTION TO GENETIC ANALYSIS SECOND EDITIONPDF电子书下载

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  • 电子书积分:24 积分如何计算积分?
  • 作 者:DAVID T.SUZUKI ANTHONY J.F.GRIFFITHS RICHARD C.LEWONTIN
  • 出 版 社:W.H.FREEMAN AND COMPANY
  • 出版年份:1981
  • ISBN:0716712636
  • 页数:911 页
图书介绍:
《AN INTRODUCTION TO GENETIC ANALYSIS SECOND EDITION》目录
标签:

Introduction 1

Genetics in Biology 1

Genetics and Human Affairs 2

Chapter 1 Gene and Organism 9

Gene and Environment 11

Genotype and Phenotype 14

The Norm of Reaction 15

Developmental Noise 19

Variation Is the Raw Material of Genetic Analysis 21

Summary 23

Chapter 2 Mendelism 27

Mendel’s Experiments 28

Simple Mendelian Genetics in Humans 45

Simple Mendelian Genetics in Agriculture 48

The Origin of Variants 51

Genetic Dissection 52

Summary 53

Problems 54

Chapter 3 Chromosome Theory of Inheritance 63

Mitosis and Meiosis 63

The Chromosome Theory of Heredity 68

Sex Chromosomes in Other Species 82

The Chromosome Theory in Review 86

Mendelian Genetics in Less Familiar Sexual Cycles 88

Summary 96

Problems 97

Chapter 4 Extensions to Mendelian Analysis 103

Variations on Dominance Relations 104

Multiple Alleles 107

Lethal Genes 113

Several Genes Affecting the Same Character 116

Penetrance and Expressivity 122

Summary 125

Problems 126

Chapter 5 Linkage 135

The Discovery of Linkage 135

Recombination 140

Linkage Symbolism 144

Linkage of Genes on the X Chromosome 144

Linkage Maps 145

Three-Point Testcross for Linkage Detection 148

Double Crossovers 152

The x2 Test 158

Early Thoughts on the Nature of Crossing Over 161

Linkage Mapping by Recombination in Humans 167

Summary 169

Problems 169

Chapter 6 Advanced Transmission Genetics 177

Mapping Functions 177

Tetrad Analysis 184

Mitotic Segregation and Recombination 199

Mapping Human Chromosomes 205

Summary 210

Problems 210

Chapter 7 Gene Mutation 219

Somatic Versus Germinal Mutation 220

Types of Mutations 222

The Usefulness of Mutations 226

Mutation Detection Systems 226

Selective Systems 229

Mutation Induction by Mutagens 242

The Mutant Hunt 245

Mutation Breeding 247

Summary 250

Problems 250

Chapter 8 Chromosome Mutation 255

Cytological Properties of Chromosomes 256

Changes in Chromosome Structure 260

Changes in Chromosome Number 284

Chromosome Mechanics in Plant Breeding 302

Summary 304

Problems 305

Chapter 9 Recombination in Bacteria and Their Viruses 317

Bacterial Conjugation 318

Bacterial Transformation 339

Phage Genetics 343

Transduction 356

Summary 362

Problems 363

Chapter 10 The Nature of the Gene 371

Position Effect 373

Intragenic Recombination 373

Intragenic Complementation 380

How Genes Work 385

Gene-Protein Relations 395

Temperature-Sensitive Alleles 410

Genetic Dissection of Genes 411

Summary 411

Problems 412

Chapter 11 DNA Structure 425

The Structure of DNA 426

Replication of DNA 434

DNA and the Gene 452

The Genetic Code 455

Alternative DNA Models 461

Summary 462

Problems 463

Chapter 12 DNA Function 467

Transcription 468

Translation 472

Cracking the Code 480

Summary 492

Problems 493

Chapter 13 Manipulation of DNA 501

The Power of Base Complementarity 502

Genetic Engineering 526

Summary 549

Problems 550

Chapter 14 The Structure and Function of Chromosomes 555

Constitutive Heterochromatin 556

Facultative Heterochromatin 563

Eukaryote Gene Function and Organization 572

Genes with Related Functions 585

Summary 656

Problems 656

Chapter 15 Organelle Genes 615

Variegation in Leaves of Higher Plants 618

Poky Neurospora 622

The Heterokaryon Test 624

Shell Coiling in Snails: A Red Herring 624

Extranuclear Genes in Chlamydomonas 626

Extranuclear Genes in Bakers’ Yeast 637

How Many Copies? 653

Other Examples of Extranuclear Inheritance 653

Summary 656

Problems 656

Chapter 16 Mechanisms of Genetic Change 663

Gene Mutation 664

Recombination 690

Transposable Genetic Elements 703

Summary 720

Problems 721

Chapter 17 Developmental Genetics 727

Development as a Regulated Process 727

Differentiation and Variable Gene Activity 741

Immunogenetics: The Immune System as a Developmental Model 762

Developmental Genetics of Drosophila 775

Summary 797

Problems 798

Chapter 18 Quantitative Genetics 807

Some Basic Statistical Notions 809

Genotypes and Phenotypic Distribution 818

Norm of Reaction and Phenotypic Distribution 821

The Heritability of a Trait 823

Determining Norms of Reaction 826

Quantifying Heritability 831

Counting and Locating the Genes 837

Gene Action 840

More on Analyzing Variance 840

Summary 847

Problems 848

Chapter 19 Population Genetics 853

Darwin’s Revolution 854

Variation and Its Modulation 855

The Sources of Variation 867

The Effect of Sexual Reproduction on Variation 873

Selection 881

Balanced Polymorphism 891

Multiple Adaptive Peaks 894

Artificial Selection 897

Random Events 899

A Synthesis of Forces 901

The Origin of Species 905

Summary 906

Problems 908

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