后基因组技术及现代天然产物进展 第七届国际后基因组技术论坛及中日韩天然产物论坛论文集 英文版PDF电子书下载

PLENARY LECTURESNONINVASIVE PERSONALIZED GENOMICS&Charles R.Cantor 1

TOOLS FOR GENE EXPRESSION ANALYSIS OF SINGLE-CELLS&Kambara Hideki 2

TRANSLATING PHARMACOGENETICS AND PHARMACOGENOMICS INTO PERSONALIZED MEDICINE&Zhou Honghao,MD 4

INVITED LECTURESBIOACTIVE MARINE NATURAL PRODUCTS:DRUG LEADS AND CELL BIOLOGY TOOLS&Ra ymonad Andersen 5

BIOLOGICAL ACTIVITY STUDY OF CHINESE MEDICINE BASED ON METABOLIC FINGERPRINTING ANALYSIS&Chai Yifeng 6

IDENTIFICATION OF TWO NOVEL SESQUITERPENES FROM SCHISANDRA CHINENSIS WITH ANTI-INFLAMMATORY EFFECT&Choi Youngwhan 7

A NEW MENAQUINONE BIOSYNTHETIC PATHWAY,DIVERSITY OF THE EARLY STEP OF THE PATHWAY&Tohru Dairi 9

AUTOMATED DROPLET-BASED MICROFLUIDIC SYSTEMS FOR HIGH-THROUGHPUT SCREENING AND SINGLE CELL ANALYSIS&Fang Qun,Du Wenbin,Gu Shuqing,et al. 10

CHEMILUMINESCENT AND ELECTROCHEMILUMINESCENT IMMUNOSENSOR FOR MULTIANALYTE ASSAY&Fu Zhifeng 12

METABOLOMICS AND ITS APPLICATION TO HIGH RESOLUTION PHENOTYPE ANALYSIS&Eiichiro Fukusaki 13

THE ISOLATED FAMILIAR PSP CAUSED BY ALU-MEDIATED FLCN INTRAGENIC LARGE DELETIONS&Ding Yibing,Zhu Chengchu,Min Haiyan,et al. 15

QUANTITATIVE ANALYSIS AND VISUALIZATION OF TRANSIENT REGULATORY PROTEIN MODIFICATIONS AND INTERACTIONS IN SINGLE CELLS USING DUOLINK&Mats Gullberg 16

MONODISPERSED MOLECULARLY IMPRINTED POLYMERS FOR AFFINITY-BASED SEPARATION AND EXTRACTION&Jun Haginaka 17

HIGH THROUGHPUT SEQUENCING OF IMMUNE REPERTOIREFOR BIOMARKER DISCOVERY&Han Jian,MD.,Ph.D. 19

APPLICATION OF ENVIRONMENTAL GENOME RESOURCES AND THE SINGLE CELL BASED TECHNOLOGY&Haruko Takeyama 21

THE ROLES OF FXR IN CARDIOVASCULAR DISEASES&He Fengtian 23

APPLICATION OF MAGNETIC NANOPARTICLES IN HIGH-THROUGHPUT SINGLE NUCLEOTIDE POLYMORPHISMS(SNPs)AND COPY NUMBER VARIATIONS(CNVs)ANALYSIS&He Nongyue 24

APATMER BASED ANALYTICS OF BIOCHEMICALS AND PHARMACEUTICALS&Wang Jian,Huang Chengzhi 27

FD-LC-MS/MS METHOD DEMONSTRATING BIOMARKER CANDIDATE PROTEINS AND INTRACELLULAR SIGNALING OF PROTEINS&Kazuhiro Imai and Tomoko Ichibangase 30

CHIRALITY TRANSFER IN PEPTIDE BASEDN-AMIDOTHIOREAS&Jiang Yunbao 32

SPECIFIC ASSAY AND DYNAMIC MONITORING OF CELL SURFACE CARBOHYDRATES&Ju Huangxian 33

SYNTHESIS OF NATURAL PRODUCTS BEARING BENZOPYRANS MOIETY BY A DOMINO REACTIONS&Wang Xue,Xia Likai,Li Xin,et al. 35

MICROARRAY-BASED HIGH-THROUGHPUT LABEL-FREE MIRNA EXPRESSION PROFILING FROM TOTAL RNA&Duan Demin,Zheng Kexiao,shen Ye,et al. 37

APPLICATION OF PROOFREADING POLYMERASE IN GENETIC ANALYSIS&Li Kai 38

HIGHLY SENSITIVE DETECTION OF MICRORNAS BY USING TECHNIQUES OF NUCLEIC ACID AMPLIFICATION&Li Zhengping,Wang Honghong,Jia Hongxia,et al. 39

DEVELOPMENT OF ANALYTICAL METHODS FOR CELL CULTURE AND METABOLISM BASED ON COMBINATION OF MICROFLUIDIC DEVICES AND MASS SPECTROMETRY&Lin Jinming,Gao Dan.Wei Huibin 41

BIO-APPLICATIONS OF APTAMER&Lin Junsheng,Diao Yong 43

ION TORENT-REVOLUTIONARY SEQUENCING TECHNOLOGY&Dr.David Lin(Lin Wei) 44

COUNTING EVERY mRNA MOLECULE IN SINGLE CELLS REVEALS ALLOMETRIC SCALING OF THE TRANSCRIPTOME&Linnarsson Sten 45

NEURONAL ANALYSIS OF C.ELEGANS ON A MICROFLUIDIC CHIP&Wang Jingjing,Feng Xiaojun,Du Wei,et al. 46

FABRICATION OF SOLID NANOPORES AND ITS APPLICATION IN THE BIOSENSORS&Liu Quanjun,Liu Liping,Sun Feng,et al. 49

ACCESSING GENOMIC INFORMATION FROM A SINGLE CELL&Dirk L？ffert 50

SOME PROGRESSES ON AG？NEW GENERATION OF DNA SEQUENCERS&Lu Zuhong 51

SYSTEMS BIOLOGY FOR THE RESEARCH OF TCM&Luo Guoan,Liang Qionglin and Wang Yiming 52

GENE EXPRESSION ANALYSIS USING LONG-TERM PRESERVED FORMALIN-FIXED AND PARAFFIN-EMBEDDED TISSUE OF NON-SMALL CELL LUNG CANCER&Ali Moshfegh 54

NATURAL KILLER CELL IMMUNE SURVEILLANCE AT THE SINGLE CELL LEVEL&Bj？orn ？nfelt 55

EFFICIENT APPROACH TO SYNTHESIS OF NOVEL HETEROCYCLES&Dongsoo Shin 56

THE FORMATION OF REACTIVE OXYGEN SPECIES DURING POLYCHLORINATED BIPHENYL METABOLISM IN HEPG2 CELLS&Liu Jing,Liu Lichao,Ma Xiaoyan,et al. 58

TUMOR NECROSIS FACTOR(TNF)-α UPREGULATES PROGESTERONE RECEPTOR-A BY ACTIVATING THE NF-кBSIGNALING PATHWAY IN HUMAN DECIDUA AFTER LABOR ONSET&Sun Lizhou 60

NANOSTRUCTURED METAL BIOSENSING SYSTEMS BASED ON LSPR FOR LABEL-FREE AND MULTIPLEX BIOSENSORS AND SERS FOR SINGLE CELL ANALYSES&Eiichi Tamiya 61

SEQUENCING OUR ENZYMES,SEQUENCING OURSELVES&Wang Chunlin 63

CARBON NANOSTRUCTURES AS ADSORBENTS FOR THE ISOLATION OF PROTEINS FROM BIOLOGICAL SAMPLES &Du Zhuo,Chen Meiling,Liu Jiawei,et al. 65

PROTEIN QUANTIFICATION USING ICP-MS WITH ELEMENT-LABELING STRATEGIES&Xu Ming,Yan Xiaowen,Yang Limin,et al. 67

ENHANCING MICROFLUIDIES BY NANOFLUIDIES FOR BIOANALYSIS&Wu Zhiyong,Tain Li,Wang Lin,et al. 69

IDENTIFICATION AND DRAFT GENOME OF DEHALOCOCCOIDES SP.STRAIN ATV1 THAT HAS REDUCTIVE DEHALOGENASES FOR TRICHLOROETHENE AND VINYL CHLORIDE,AND CAN DECHL-ORINATE TRICHLOROETHENE TO ETHENE&Masafumi Yohda,Mizuki Kitajima,Megumi Iwamoto,et al. 70

SINGLE-NANOPARTICLE-DETECTED SUSPENSION ARRAYS FOR ULTRASENSITIVE MULTIPLEXED DNA ASSAY&Han Guojun,Zhang Sichun,Xing Zhi,et al. 72

EFFECTS OF NANO-AG ON THE ADSORPTION OF AN ONTO KANDELIA CANDEL(KC)LEAVES&Y N Yang,J L Chen,H F Sun,et al. 73

PYROSEQUENCING ON A SINGLE CELL&Song Qinxin,Zhou Guohua 75

NANOTECHANOL LOGY AND NEW TECHOLOGIESA IMPROVED DUAL-COLOR METHOD FOR THE DETECTION OF SINGLE NUCLEOTIDE POLYMORPHISMS ON MAGNETIC NANOPARTICLES ARRAY&Li Song,Liu Hongna,Liu Lishang,et al. 77

AN AUTOMATIC SAMPLING SYSTEM FOR NANOPORE SENSOR&Xuan Yang,Liu Liping,Zhao Zhiliang,et al. 79

CHIRAL FLUORESCENT GOLD NANOCLUSTERS&Zhao Xijuan,Huang Chengzhi 82

COMPARISON AND VERIFICATION OF GENOMIC DNA EXTRACTION BASED ON MAGNETIC NANOPARTICLES FROM ESCHERICHIA COLI AND WHOLE BLOOD&Ma Chao,Liu Jiefeng,Wang Chun,et al. 84

CONSTRUCTION OF PROTEOME ANALYSIS SYSTEM WITH ULTRA PERFORMANCE SEPARATION USING LONG MONOLITHIC COLUMN&Hironobu Morisaka and Mitsuyoshi Ueda 87

DETECTION OF ASCORBIC ACID USING BOVINE SERUM ALBUMIN PROTECTED-SILVER NANOCLUSTERS&Yang Xiuhua,Ling Jian,Peng Jun,et al. 89

DETECTION OF HEPATITIS B VIRUS DNA BY ELECTROCHEMICAL BIOSENSOR&Xi Zhijiang,Ma Chao,Wang Fang,et al. 91

DEVELOPMENT OF A MICRO-VOLUME HYBRIDIZATION DEVICE FOR NANOPARTICLES&Liu Bin,Liu Zheng,Li Zhiyang,et al. 93

FABRICATION AND APPLICATION OF THE SELF-ASSEMBLED γ-Fe2O3@AU NANOCOMPOSITES WITH LOW FLUORESCENCE BACKGROUND&Jiang Hongrong,Zeng Xin and He Nongyue 95

FABRICATION OF CONICAL NANOPORES FOR BIOSENSORING&Sun Feng,Li Jinchao,Wu Hongwen et al. 97

FABRICATION OF NANO-ELECTRODE ON THE SURFACE OF THE SOLID-STATE NANOPORE&Ye Xiaofeng,Liu Liping,Wu Hongwen,et al. 100

GOLD NANOPARTICLES WITH DIFFERENT SIZE AS ASSISTED MATRIX FOR THE DETECTION OF SMALL MOLECULES THROUGH LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY&Qiu Fei,Huang Lequn Lee 103

HIGHLY EFFICIENT PRE-CONCENTRATION OF DNA AT A NEW MICRO-NANO JUNCTION&Zhang Dawei,Zhang Huiqin,Tian Li,et al. 106

HIGHLY SENSITIVE CHEMILUMINESCENT IMMUNOASSAY BASED ON FUNCTIONALIZED TITANIA NANOPARTICLE CARRIER FOR LOADING MULTIPLEX ENZYME-LABELING&Wang Zhenxing,Fu Zhifeng 108

MAGNETIC NANOPARTICLE-BASED CHEMILUMINESCENCE DETECTION OF SEQUENCE-SPECIFIC HBV-DNA&Wang Fang,Ma Chao,Zeng Xin,et al. 109

NOISE ANALYSIS OF SOLID-STATE NANOPORE WITH DIFFERENT SALT SOLUTIONS&Wang Yucheng,Kong Jinglin,Liu Liping,et al. 111

OPTIMIZATION OF NUCLEIC ACID QUANTITATIVE ANALYSIS BASED ON MAGNETIC NANOPARTICLES AND CHEMILUMINESCENCE DETECTION&Liu Ming,Zeng Xin,Sun Huanxiang,et al. 114

PRELIMINARY GENOTYPING FOR COX-2-765G＞C BASED ON SNP DETECTION WITH MAGNETIC NANOPARTICLES&Jia Yingying,Liu Hongna,He Nongyue 117

PREPARATION AND CHARACTERIZATION OF MAGNETIC MICROSPHERIC POLYSTYREN&Li Guopeng,Shen Bin,Li Zhiyang,et al. 119

PREPARATION AND CHARACTERIZATION OF MONODISPERSE core-SHELL Fe3O4/SiO2 MICROSPHERES&Li Chuanyan,Ma Chao,Wang Fang,et al. 121

PREPARATION OF DNA-FUNCTIONALIZED Pd NANOPARTICLES&Li Hongying,Wang Zhifei,He Nongyue 123

PROCESSING MONOSODIUM GLUTAMATE WASTE WATER BY IMMOBILIZED MONASCUS&Li Taotao,He Nongyue,Li Xiaolong,et al. 126

QUANTITATIVE INTRODUCTION OF A CELL DIFFERENTIATION INHIBITING AGENT BY THE USE OF AN AUTOMATED MICROINJECTION SYSTEM&Jihye Chung,Natsuko Miura,Kouichi Kuroda,et al. 128

SILVER NANOCLUSTERS SYNTHESIZED VIA AN APTAMER-MEDIATED APPROACH AS AN INTRACELLULAR PROTEIN SENSOR&Zhou Yawen,Huang Chengzhi 130

SURFACE MODIFICATION OF SILICON NITRIDE NANOPORE WITH CTAB&Kong Jinglin,Wang Yucheng,Liu Liping,et al. 133

SYNTHESIS AND CHARACTERIZATION OF GOLD-COATED IRON OXIDE NANOPARTICLES&Liu Hongna,Li Song,Liu Lishang,et al. 136

THEORETICAL AND EXPERIMENTAL STUDY ON CAPACITANCE CHARACTERISTIC OF SOLID-NANOPORE&Wang Xiaojuan,Liu Liping,Wu Hongwen,et al. 138

TRANSLOCATION OF λ-DNA THROUGH A SOLID-STATE NANOPORE&Wu Hongwen,ZhaoZhiliang,Liu Liping,et al. 141

VOLT-AMPERE CHARACTERISTICS OF SOLID-STATE NANOPORES FABRICATED BY FOCUSED ION BEAM&Xie Xiao,Liu Liping,Wu Hongwen,et al. 144

PROTEIN AND PROTEOMICS ANALYSISABNORMAL EXPRESSION OF GOLGI PROTEIN 73 AND DIAGNOSTIC VALUES FOR HEPATOCELLULAR CARCINOMA&Sai Wenli,Yao Dengfu,Wu Wei,et al. 147

ABNORMAL EXPRESSION OF VEGF AND ITS DYNAMIC QUANTITATIVE ANALYSIS AT THE DIFFERENT STAGES OF HEPATOCELLULAR CARCINOMA DEVELOPMENT&Qiu Liwei,Yao Dengfu,Wu Wei,et al. 150

ANALYSIS FOR VARIATIONS OF BACTERIAL COMMUNITES IN SMALL INTESTINE OF BKS-DB MICE&Hu Fang,Zhou Dongrui,Du Caihe,et al. 153

APTAMER-BASED TURN-ON FLURESCENT ASSAY FOR CELLULAR PRION PROTEIN DETECTION&Zhan Lei,Liang Lijiao,Zhen Shujun,et al. 156

CHARACTERIZATION OF BRA-MIR-172 DEGRADATION IN RNASE A,SERUM AND IN SINGLE CELL IN VITRO&Shao Youhua,Liang Gaofeng and Xiao Zhongdang 159

DIAGNOSTIC VALUES OF COMBINED HEPATOMA-SPECIFIC α-FETOPROTEIN FRACTION AND TELOMERASE IN PATIENTS WITH HEPATOCELLULAR CARCINMA&Wu Wei,Yao Dengfu,Qiu Liwei,et al. 162

DIFFERENTIAL HUMORAL RESPONSE OF GENOTYPE 1B HEPATITIS C VIRUS F PROTEIN BETWEEN CHRONIC AND RECOVERED INFECTIONS&Deng Xiaozhao,Kong Jing,Chu Chunli,et al. 165

DISPLAY TWO KINDS OF AMYLOLYTIC ENZYMES ON THE CELL SURFACE OF CORYNEBACTERIUM GLUTAMICUM,AND EFFECTIVE PRODUCTION OF GLUTAMATE FROM STARCH&Yao Wenjuan,Zhang Wei,Xu Xiaole,et al. 168

EFFECT OF ANTI-TNF-α MAB ON NF-кB NUCLEAR TRANSLOCATION AND PROLIFERATION OF HUMAN HEPG2 CELLS&Zhang Haijian,Yao Dengfu,Wu Wei,et al. 171

EVALUATION OF A CO-DELIVERY COMPLEX COMPRISING A P53-BASED ANTITUMOR MINIPROTEIN AND A GENE&Chen Zhangbao,Li Chong,Zhang Xiaolin,et al. 174

EXPRESSION OF THERMOSTABLE RECOMBIANT LUCIOLALATERALIS LUCIFERASE AND APPLICATION PYROSEQUENCING SYSTEM&Xu Shu,Zou Bingjie,Wang Jianping,et al. 177

GRAPHENE OXIDE/ APTAMER FLUORESCENCE SYSTEM FOR DETECTION OF PRION PROTEIN&Zhuang Honglin,Huang Chengzhi 180

HEPATITIS C VIRUS F PROTEIN UP-REGULATES BCL-2 AND BAX IN HUMAN HEPATOMA HEPG2 CELLS&Wei Juan,Deng Xiaozhao,Kong Jing,et al. 182

HMGA2:A BIFUNCTIONAL PROTEIN IN TUMORIGENESIS AND ANGIOGENESIS&Wang Qizhao,Lv Yinghui and Gong Yuhua 185

ICAM-1 EXPRESSION ALTERATION IN SCIATIC NERVES FOLLOWING NERVE INJURY&Yang Junling,Yao Dengfu,Wu Wei,et al. 188

IMPAIRMENT OF CHLORPYRIFOS ON SPERMATOGENESIS OF MALE MICE&Ruan Qin L.,Ju Jing J.,Li Yun H.,et al. 191

INVESTIGATION OF THE MOLECULAR BASIS OF MOONLIGHTING PROTEIN,ENOLASE,IN THE POST-GENOME STUDY&Natsuko MIURA,Kazuma MATSUI,Satoshi ENDO,et al. 194

MOLECULAR BREEDING OF LUCIFERASE SUITABLE FOR PYROSEQUENCING BY CELL SURFACE ENGINEERING&Tatsuya Fushimi,Hideya Shintani,Natsuko Miura,et al. 196

PROKARYOTIC EXPRESSION,ANTISERUM POLYCLONAL ANTIBODY PREPARATION AND IDENTIFICATION OF IZUMO1 IN RAT TESTES&Gu Chen,Liu Jing,Jia Tianrong,et al. 198

PROTEOMICS ANALYSIS OF CLEAR CELL RENAL CELL CARCINOMA:IDENTIFICATION OF POTENTIAL TUMOR MARKERS&Sun Chuanyang,Li Jinmei,Sun Wei,et al. 202

PROTEOMICS ANALYSIS OF SERUM PROTEIN PROFILING IN CERVIAL CANCER PATIENTS BY DIGE&Ye Nengsheng,Duan Caiying and Gu Xuexin 205

PULMO-TRACKING OF GLUTATHIONE S-TRANSFERASE IN MAMMAL&Fu Ailing,Yan Haitao 208

RECOMBINATION CYTOGLOBIN ANTI-OXIDATION AND ITS BIOLOGICAL EFFECTS&Li Zhaofa,Hui Erjing and Wang Qizhao 211

RNA POLYMERASE Ⅱ AS A LINK BETWEEN ALTERNATIVE SPLICING AND CHROMATIN STRUCTURE&Yu Shuangxin,Huang Huan,Liu Hongde,et al. 214

ROLE OF NOTCH SIGNAL IN NEURAL DIFFERENTIATION OF HMSCS INDUCED BY SODIUM FERULATE&Deng Zhifeng,Lou Yuanlei,Tu Wei,et al. 217

SUBCELLULAR LOCALIZATION OF ZNFD:A NOVEL HUMAN ZINC FINGER PROTEIN AND THE EXPRESSION AND ITS SIGNIFICANCE OF ZNFD IN PROSTATE CANCER TISSUES&Cheng Hongxia,Wang Weiping,Sun Libing,et al. 220

THE EFFECT OF HCV F AND CORE PROTEIN ON THE APOPTOSIS OF HEPG2 CELLS&Chu Chunli,Deng Xiaozhao,Kong Jing,et al. 223

WESTERN BLOTTING VIA PROXIMITY LIGATION FOR HIGH PERFORMANCE PROTEIN ANALYSIS&Gu Jijuan,Liu Yanling,Ola S？derberg,et al. 226

NUCLEIC ACID ANALYSISA CLOSED-TUBE DETECTION OF PRODUCTS FROM LOOP-MEDIATED ISOTHERMAL AMPLIFICATION(LAMP)BY USING A WAX-SEALED FLURESCENT INTERCALATOR&Liang Chao,Cheng Sijia,Chu Yanan,et al. 227

A NOVEL MICROFLUIDIC CHIP BASED ON HIGH DENSITY BEADS FOR DNA SEQUENCING&Ma Xiaodong,Zhao Hong,Lu Zuhong 230

A REGULATION MECHANISM FOR CD274 OVER-EXPRESSION IN GASTRIC CANCER&Wang Weipeng,Sun Jing,Li Fang,et al. 233

ABERRANT MIRNA EXPRESSION RESPONSE TO UV IRRADIATION IN HEPG2 CELLS&Zhu Yanliang,Liang Gaofeng,Xiao Zhongdang 236

ANALYSIS OF MULTIPLEX LOOP-MEDIATED ISOTHERMAL AMPLIFICATION(MLAMP)PRODUCTS BASED ON NICKING MEDIATED SEQUENCE-TAGGED PYROSEQUENCING&Liang Chao,Chu Yanan,Cheng Sijia,et al. 239

ASSOCIATION ANALYSIS OF GENES RELATED TO ELECTRON TRANSFER FOR SHEWANELLA ONEIDENSIS MR-1&Fu Yaxing,Sun Xiao 244

ASSOCIATION BETWEEN CYP11A1 GENE SNP RS4077582 POLYMORPHISM AND POLYCYSTIC OVARY SYNDROME IN CHINESE WOMEN&Zhang Chengwei,Zhang Xinlin,Xu Pei,et al. 247

ASSOCIATION OF CYP3A418B POLYMORPHISMS WITH THE PHARMACOKINETICS OF TACROLIMUS IN CHINESE RENAL TRANSPLANT RECIPIENTS&Li Danying,Teng Ruichen,Fang Yun 250

ASYMMETRIC NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION(ASYMMETRIC-NASBA):A DIFFERENT METHOD OF CONVENTIONAL NASBA&Jia Huning,Chen Zhiyao,Wu Haiping,et al. 253

CHARACTERIZATION OF RECOMBINANT SINGLE-STRAND BINDING PROTEIN FROM ESCHERICHIA COLI AND ITS APPLICATION IN PYROSEQUENCING&Wang Jianping,Zou Bingjie,Chen Zhiyao,et al. 256

CLONING AND CHARACTERIZATION OF A NOVEL METALLOTHIONEIN cDNA FROM KANDELIA CANDEL&Zhang Fengqin,Wang Youshao,Li Xiaolong,et al. 260

CLONING OF FULL-LENGTH HUMAN ESTROGEN RECEPTOR AND CONSTRUCTION OF THE EXPRESSION VECTOR IN YEAST&Zheng Chenna,Yang Huiyong,Li Qingsong,et al. 263

COMPARATIVE ANALYSIS OF C-TYPE CYTOCHROMES IN TWENTY SHEWANELLA GENOMES&Liu Biyun,Sun Xiao 266

CONSTRUCTION OF EXPRESSION VECTORS OF FKBP38 AND RHEB GENE AND THEIR CO-TRANSFECTION INTO CASHMERE GOAT FETAL FIBROBLASTS STABLY&Wang Xiaojing,Liang Yan,Wu Manlin et al. 269

CONSTRUCTION OF MIR-145 EUKARYOTIC EXPRESSION VECTOR AND ITS STABLE EXPRESSION IN HUMAN COLON CANCER CELLS&Liang Gao feng,Hu Feihu,Chen Shanshan,et al. 272

CONSTRUCTION OF PLASMID CONTAINING HUMAN ARGONAUTE2 GENE&Chen Shanshan,Zeshan Basit,Tian Tian,et al. 275

DEVELOPMENT AND APPLICATION OF PLUG MARKERS FOR IDENTIFYING THINOPYRUM INTERMEDIUM CHROMOSOME 1ST IN WHEAT BACKGROUND&Hu Lijun,Song Xiaojin,Ran Ling,et al. 278

DEVELOPMENT OF MULTIPLEX LOOP MEDIATED ISOTHERMAL AMPLIFICATION METHOD FOR THEZ SIMULTANEOUS DETECTION OF HBV,HCV,HIV AND TP&Liang Chao,Cheng Sijia,Chu Yanan,et al. 281

DIFFERENTIAL EXPRESSION AND TARGET PREDICTION OF MICRORNAS IN HIPPOCAMPUS IN SEVOFLURANE-ANESTHETIZED RATS&Pan Zhiqiang,Li Yangqiang,Hao Lingyun,et al. 285

DOWN-REGULATION OF MICRORNA-139-5P IN ESOPHAGEALSQUANMOUS CELL CARCINOMA&Sheng Jingyi,Liu Ran,Yang Miao,et al. 288

DYNAMICS STUDIES OF EXOGENOUS MIRNA TRANSFECTION BY LIVE-CELL MICROSCOPY AND SINGLE PARTICLE TRACKING&Wang Yuanyuan,Tian Tian,Xiao Zhongdang 292

EFFICIENCY COMPARISON OF THREE NUCLEIC ACID EXTRACTION KITS FOR EXTRACTING BLOOD VIRUS&Wang Cong,Chen Zhiyao,Wu Haiping,et al. 295

EXPRESSION OF MIRNAS RELATIVED WITH ANGIOGENESIS AND VEGF SIGNALING IN RESPONSE TO HYPOXIA IN HUVEC&Liu Fen,Lou Yuanlei,Xie An,et al. 298

GENE EXPRESSION PROFILING OF AD3 INFECTED HEP2 CELL LINE&Qi Yuhua,Guo Xiling,Cui Lunbiao,et al. 301

GENECHIP ARRAY SHOWED A PROMOTION OF GENES RELATED TO ABA BIOSYNTHESIS AND SIGNALS IN RICE SEEDLINGS AFTER THE IMPLANTATION WITH LOW-ENERGY NITROGEN ION BEAM&Ya Huiyuan,Liang Gaofeng,Chen Qiufang,et al. 304

GENETICALLY MODIFIED ORGANISMS ANALYSIS BY PYROSEQUENCING ON A PORTABLE PHOTODIODE-BASED BIOLUMINESCENCE ANALYZER&Song Qinxin,Zhou Guohua 307

GENOTYPING THREE SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH RISK OF GOUT BY IMPROVED TRI-PRIMER PCR&Yang Huiyong,Xu Chaochen,Zhou Guohua,et al. 310

HYDROGEL MICROARRAY FOR LOW-COST SNP SCREENING&Wang Hui,Chen Zhiyao,Li Youzhi,et al. 313

IGF-Ⅱ SILENCING INHIBITED HEPG2 CELL PROLIFERATION AND PROMOTING ANOIKIS&Yao Ninghua,Yao Dengfu,Xu Wei,et al. 316

INFORMATICS AND ALTERATIONS OF HEPATIC GENE EXPRESSION PROFILES DURING HEPATOCYTE MALIGNANT TRANSFORMATION&Yao Dengfu,Wang Li,Yu Dandan,et al. 319

INTERACTION STUDIES OF 6-ALKYLAMINO SUBSTITUTED NAPHTHALIMIDES AND DNA&Xie Lijuan 322

KINETICS OF MICRORNA-146A EXPRESSION IN LIPOPOLYSACCHARIDE-INDUCED ALVEOLAR MACROPHAGES&Zeng Zhenguo,Qian Kejian,LiuFen,et al. 325

MICRORNAS AND THE UPREGULATION OF CYTOGLOBIN IN ACTIVATED HEPATIC STELLATE CELLS&Lv Yinghui,Wang Qizhao,Diao Yong,et al. 328

MIR-192 AND MIR-215 INHIBIT NUCLEOTIDE EXCISION REPAIR BY TARGETING ERCC3 IN A549 CELL LINE&Li Yong,Xu.Li Y.,Fu.Bi Q.,et al. 331

MIR-210 UP-REGULATES VEGF SIGNALING FOR ANGIOGENESIS IN VITRO&Lou Yuanlei,Deng Zhifeng,Guo Fei,et al. 334

MODULATION OF TNBS-INDUCED COLITIS BY ELECTOPORATION-MEDIATED KALLISTATIN GENE THERAPY&Diao Yong,Dong Hao,Wang Qizhao 337

MOLECULAR ASSEMBLY OF DNA APTAMER AND PHOTOSENSITIZER FOR TARGETING CANCER THERAPY&Wang Jian,Zhu Guizhi,You Mingxu,et al. 341

MRNA ANALYSIS OF MULTICELLULAR SPHEROID WITH A SCANNING PROBE MICROSCOPY SYSTEM&Hitoshi Shiku,Genki Saito,Yuanshu Zhou,et al. 343

MULTIPLEX ALLELE-SPECIFIC AMPLIFICATION FROM WHOLE BLOOD DIRECTLY&Zhu Jianjie,Chen Lanxin,Chen Xihua,et al. 345

MULTIPLEXED LUMINEX XMAP ASSAY FOR DETECTION OF MICRORNAS&Ge Yiyue,Cui Lunbiao,Qi Yuhua,et al. 348

NEW SPECIFIC EST-SSR MARKERS FOR TARGETING SECALE AFRICANUM CHROMOSOMES 2R A&Lei Mengping,Song Xiaojin,Ran Ling,et al. 351

NOTCH SIGNALING-RELATED MICRORNAS EXPRESSION PATTERN OF HUMAN INDUCED PLURIPOTENT STEM CELLS DIFFERENTIATING TOWARD NEURAL CELLS&Liao Wei,Lou Yuanlei,Guo Fei,et al. 354

ONE-STEP GENOTYPING BY ALLELE-SPECIFIC AMPLIFICATION FROM WHOLE BLOOD&Chen Lanxin,Zhu Jianjie,Chen Xihua,et al. 357

OVEREXPRESSION OF ELFN2 IN GLIOMA REGULATED BY GENE PROMOTER HYPOMETHYLATION&Liu Xiaoping,Yu Zhibin,Wang Zeyou,et al. 360

PHYLOGENETIC ANALYSIS OF ASPM,A BRAIN-VOLUME-RELATED GENE IN VERTEBRATES&Ye Yu,Zhang Jingshu,J esse Liling 363

PREPAREATION OF MONOVALENT CIRCULAR SSDNA APTAMER BY ENZYME LIGATION&Yang Li,Diao Yong and Yang Huiyong 366

PYROSEQUENCING-BASED BARCODES FOR DYE-FREE MULTIPLEX BIOASSAY&Chen Zhiyao,Zhang Xiaodan,Liu Xiqun,et al. 369

RAPID SCREENING AND GENOTYPING OF AVIAN INFLUENZA VIRUS BY VISUAL ISOTHERMAL AMPLIFICATION&Chu Yanan,Cheng Sijia,Liang Chao,et al. 374

RESEARCH ON THE DESIGN TECHNIQUE OF METAGENOME TARGETED ANALYSIS CAPTURE PROBE OF MICROBIAL COMMUNITY IN LIQUOR FERMENTATION&Ge Qiusha,Fan Yucai,Zhou Dongrui,et al. 376

REVERSE SEQUENCING BY HYBRIDIZATION WITH FLUORESCENCE INCORPORATION&Li Yanqiang,Pan Zhiqiang,Yang Yao,et al. 378

SIGNAL AMPLIFICATION BASED ON AFU FLAP ENDONUCLEASE COUPLED WITH NICKING ENDONUCLEASE FOR ULTRASENSITIVE DNA DETECTION&Zou Bingjie,Ma Yinjiao,Wu Haiping,et al. 381

SENSITIVE DETECTION OF MICRORNAS WITH SIMPLIFIED LOOP-MEDIATED ISOTHERMAL AMPLIFICATION(LAMP)&Li Zhengping,Liu Xiaoling,Li Cuiping,et al. 384

SINGLE CELL PYROSEQUENCING USING IMPROVED LINEAR-AFTER-THE-EXPONENTIAL(ILATE)-PCR&Song Qinxin,Zhou Guohua 387

SIRNAS-MEDIATED KNOCKDOWN OF F GENE INHIBITS THE TARGET CELL GROWTH AND ITS ANCHORAGE-INDEPENDENT GROWTH&Kong Jing,Deng Xiaozhao,Chu Chunli,et al. 390

SIGNAL AMPLIFICATION BY COUPLING INVASIVE REACTION WITH HYPERBRANCHED ROLLING CIRCLE AMPLIFICATION&Zou Bingjie,Ma Yinjiao,Wu Haiping,et al. 393

SNP RS2470152 IN CYP19 IS CORRELATED TO AROMATASE ACTIVITY IN CHINESE PCOS WOMEN&Zhang Xinl,Zhang Chengw,Xu Pei,et al. 396

SPECIFIC MIRNA SILENCING HYPOXIA-INDUCIBLE FACTOR-lα EXPRESSION TO INHIBIT OF HEPG2 CELL PROLIFERATION&Dong Zhizhen,Yao Dengfu,Yao Min,et al. 400

THE EFFECTS OF LANTHANUM CHLORIDE ON TUMOR-ASSOCIATED MICRORNAS EXPRESSION&Liu Sisun,Yu Lingfang,Peng Yan,et al. 403

THE HLA PROFILING IN NASOPHARYNGEAL CARCINOMA BY COMPREHENSIVE GENTIC ASSOCIATION STUDY&Tang Minzhong,James A.Lautenberger,Gao Xiaojiang,et al. 406

THE REGULATION OF ANGIOGENESIS BY MICRORNA-210-MEDIATED HIF-1α/VEGF SIGNALING PATHWAYS AFTER RENAL ISCHEMIA/REPERFUSION INJURY&Li He,Wang Yang,Liu Fen,et al. 409

TN-SEQ:A ROBUST TECHNOLOGY FOR CHARACTERIZATION OF GENE FUNCTION IN POST-GENOME STAGE&Liao Guojian,Wang Lei,Hu Changhu 412

INFLUENCE OF F PROTEIN ON OUTCOME OF HEPATITIS C VIRUS INFECTION AMONG INJECTION DRUG USERS&Wang Jie,Zhang Yun,Yang Jingjing,et al. 415

PHYLOGENETIC CHARACTERIZATION OF HANTAVIRUSES FROM WILD RODENTS IN SOUTHEAST COASTAL REGION OF CHINA,1981—2007&Yao Pingping,Zhu Hanping,Deng Xiaozhao,et al. 419

NATURAL PRODUCTS AND PHARMACEUTICAL ANALYSISA ZINC COMPLEX OF IMIDAZOLIUM DERIVATIVE FOR THE FLUOROPHOTOMETRIC DETERMINATION OF AMOXICILLIN&Yang Jinghua,Liang Lijiao,Wang Huijuan,et al. 423

ATOMIC FORCE MICROSCOPY INVESTIGATION OF THE MORPHOLOGY AND MECHANICAL PROPERTIES OF CELL RESPONSE TO ANTIBIOTIC TREATMENT&Wang Qing,Chen Tong,Yang Xiaohai,et al. 425

CULTURE CONDITIONS FOR YIELD IMPROVEMENT USING A THREONINE-PRODUCING ESCHERICHIA COLI STRAIN&Kong JIng,Chen Jun and Wu Jie 428

CYTOTOXIC INTERATIVE EFFECTS OF CONSTITUENTS FROM RHIZOMA COPTIS&Chen Hong ying,Ye Xiaoli,Jin Yanan,et al. 431

CYTOTOXICAL EFFECT OF N-METHYL-N′-NITRO-N-NITROSOGUANIDINE ON MGMT DEFICIENT ESOPHAGEAL EPITHELIAL CELLS WAS RELATED TO THE INDUCED EXPRESSION OF HMSH2&Su Yaoyao,Liu Ran,Sheng Jingyi,et al. 434

DETERMINATION OF GUANOSINE 3′,5′-BIS(DIPHOSPHATE)BY CAPILLARY ELECTROPHORESIS WITH UV DETECTION&Feng Zijie,Huang Chengzhi 437

EFFECTS OF SURFACTANT ON THE MORPHOLOGY OF Zn2 SiO4:Mn IN SINTERING PROCESS&Li Xiaolong,Zhang Fengqin,Ma Chao,et al. 440

ELECTROSPINNING VASCULAR SCAFFOLDS OF POLY(L-LACTIDE)&Ji Xuyuan,Guo Lingling,Jin Lian,et al. 442

FACTORS INFLUENCING PHALAENOPSIS TRANSFORMATION BY PARTICLE BOMBARDMENT&Fan Shuguo 444

HIGHLY SELECTIVE RECOGNITION OF GUANOSINE PHOSPHATES ON THE BASIS OF ZN(Ⅱ)-CONTROLLED"ON-OFF-ON"CHARGE TRANSFER FLUORESCENCE OF 1,4-BIS(IMIDAZOL-1-YLMETHYL)BENZENE&Liang Lijiao,Li Yuanfang,Huang Chengzhi 447

ISOLATION AND SOME OPTIMIZATION CULTURE CONDITIONS OF SODIUM DODECYL BENZENE SULFONATE(SDBS)-DEGRADING BACTERIUM&Li Zhiyang 450

MEKC-CL DETECTION OF BIOGENIC AMINES USING TRIVALENT COPPER CHELATE AS CL ENHANCER&Li Tao,Xie Haoyue,Fu Zhifeng 453

OPTIMIZATION OF CULTURE MEDIUM FOR THREONINE PRODUCTION OF ESCHERICHIA COLI&Gu Xu,Kong Jing,Jia Jianbo,et al. 454

PROTECTIVE EFFECT OF ZIGE LYOPHILIZED POWDER ON HUMAN UMBILICAL VEIN ENDOTHEILIAL CELLS HYPOXIA/REOXYGENATION INJURY&Zhang Congcong,Ma Qiang,Chen Gang,Xu Xiaoyu 457

SURFACE-ENHANCED RAMAN SCATTERING INVESTIGATIONS ON THE INTERACTIONS OF PRION PROTEIN WITH ITS APTAMER&Hu Pingping and Huang Chengzhi 458

THE COMPARISON OF GABA WITH TAURINE AS A SCAVENGER OF THE LIPID PEROXIDATION PRODUCT MALONDIADEHYDE:A STUDY IN VITRO&Deng yan,He Nongyue,Fu Juan,et al. 460

THE INFLUENCE OF LAMOTRIGINE ON AMINO ACID NEUROTRANSMITTERS LEVEL IN THE PTZ-INDUCED STATUS EPILEPTICUS RAT HIPPOCAMPUS&Deng Yan,Ma Chao,Fu Juan,et al. 462