姚开泰院士集PDF电子书下载

第一部分 奋斗历程 1

姚开泰院士介绍 3

姚开泰院士自述 7

三阳开泰展新篇仁心妙手著人生——记中国科学院院士、著名肿瘤病理生理学家姚开泰 9

与时俱进，引领学科潮流——记姚开泰院士的肿瘤研究历程 14

第二部分 学术贡献 17

一、姚开泰院士的学术成就与学术思想 19

二、姚开泰院士的主要学术论文 25

The Enforced Expression of c-Myc in Pig Fibroblasts Triggers Mesenchymal-epithelial Transition （MET） via F-actin Reorganization and RhoA/Rock Pathway Inactivation 25

MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells 42

Embryonic Stem Cells Markers SOX2， OCT4 and Nanog Expression and their Correlations with Epithelial Mesenchymal Transition in Nasopharyngeal Carcinoma 63

Aldehyde Dehydrogenase 1， a Functional Marker for Identifying Cancer Stem Cells in Human Nasopharyngeal Carcinoma 79

Neoplastic Spindle Cells in Nasopharyngeal Carcinoma Show Features of Epithelial-mesenchymal Transition 98

Gene Expression Profile Changes and Possible Molecular Subtypes in Differentiated-type Nonkeratinizing Nasopharyngeal Carcinoma 111

Target-specific Cellular Uptake of Taxol-loaded Heparin-PEGfolate Nanoparticles 128

GenCLiP： a Software Program for Clustering Gene Lists by Literature Profiling and Constructing Gene Co-occurrence Networks Related to Custom Keywords 145

Lentivirus-mediated RNAi Silencing Targeting ABCC2 Increasing the Sensitivity of a Human Nasopharyngeal Carcinoma Cell Line against Cisplatin 160

Identification of Label-retaining Cells in Nasopharyngeal Epithelia and Nasopharyngeal Carcinoma Tissues 173

An Imageable Metastatic Treatment Model of Nasopharyngeal Carcinoma 186

Frequent Hypermethylation of RASSF1A and TSLC1， and High Viral Load of Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma and Matched Tumor-adjacent Tissues 197

Proteome Analysis of Anti proliferative Mechanism of 12-O-Tetradecanoylphorbol 13-Acetate on Cultured Nasopharyngeal Carcinoma CNE2 Cells 211

Association of PLUNC Gene Polymorphisms with Susceptibility to Nasopharyngeal Carcinoma in a Chinese Population 226

Identification of Differentially Expressed Genes in Metastatic and Non-metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization 238

Identification and Characterization of a Novel Nasopharyngeal Carcinoma-associated Peptide： NAP-1 252

Construction of Tree Models for Pathogenesis of Nasopharyngeal Carcinoma 265

Identification of Differentially Expressed Genes in Nasopharyngeal Carcinoma by Means of the Atlas Human Cancer cDNA Expression Array 281

Molecular Cloning of a Novel Tissue-specific Gene from Human Nasopharyngeal Epithelium 294

Expression of an Epstein Barr Virus Receptor and Epstein Barr Virus Dependent Transformation of Human Nasopharyngeal Epithelial Cells 303

Analysis of DNA Fragments and Polymerase Chain Reaction Products from the Tx Gene by Capillary Electrophoresis with a Laser-induced Fluorescence Detector Using No-gel Sieving Media 315

Cytogenetic Study on a New Epithelial Cell Line， HNE-1， Derived from Nasopharyngeal Carcinoma 322

Chemical Transformation of Human Embryonic Nasopharyngeal Epithelial Cells in vitro 329

Establishment and Characterization of Two Epithelial Tumor Cell Lines （HNE-1 and HONE-1） Latently Infected with Epstein-Barr Virus and Derived from Nasopharyngeal Carcinomas 333

用曲细精管微注射法建立绿色荧光蛋白转基因小鼠 348

人鼻咽与鼻咽癌cDNA阵谱中DNA修复相关基因表达差异的初步研究 355

金属硫蛋白-潜伏膜蛋白融合基因的体外转录调控 360

鼻咽及其邻近部位各类型癌组织中EBV DNA的原位检测 368

体外培养人胚鼻咽上皮的生物学特性观察 Ⅰ人胚鼻咽上皮体外培养 373

从死因回顾调查资料看湖南省鼻咽癌流行病学的一些特点并探索其发病机理 378

二亚硝基哌嗪诱发大鼠鼻咽癌的进一步研究 385

三、姚开泰院士的重要学术报告 393

鼻咽癌研究的回顾与展望 393

陈竺等22位中国科学院院士联名向国务院提出建议 以非典型肺炎防治为切入点构筑我国预防医学创新体系 399

四、姚开泰院士学术年表 402

姚开泰院士担任第一作者或通讯作者SCI收录的英文论文 402

姚开泰院士担任第一作者或通讯作者非SCI收录的英文论文 407

姚开泰院士担任第一作者或通讯作者的中文论文 408

姚开泰院士参加工作的英文论文 422

姚开泰院士参加工作的中文论文 425

姚开泰院士获得的科研成果 429

姚开泰院士获得的荣誉称号 431

第三部分 治学之道 433

创建“中南大学肿瘤研究所” 435

第四部分 大师风范 439

姚老师对生物信息学的机敏 441

与姚老师相知 442

慕名从师 443

记姚老师二三事 444

与时俱进、诲人不倦的院士——记我的导师姚开泰教授 446

我和姚老师的师生情缘 447

第五部分 社会影响 449

姚开泰院士参加的学术活动、承担的科研项目、担任的学术职务 451

各大媒体对姚开泰院士的评价 454

姚开泰院士先进事迹 457

在姚开泰院士八十寿诞暨从医六十周年庆祝宴会上的讲话 459

与时俱进 克癌攻坚——记我国鼻咽癌病理研究专家姚开泰院士 461

第六部分 人生风采 465