第一部分 奋斗历程 1
姚开泰院士介绍 3
姚开泰院士自述 7
三阳开泰展新篇仁心妙手著人生——记中国科学院院士、著名肿瘤病理生理学家姚开泰 9
与时俱进，引领学科潮流——记姚开泰院士的肿瘤研究历程 14
第二部分 学术贡献 17
一、姚开泰院士的学术成就与学术思想 19
二、姚开泰院士的主要学术论文 25
The Enforced Expression of c-Myc in Pig Fibroblasts Triggers Mesenchymal-epithelial Transition （MET） via F-actin Reorganization and RhoA/Rock Pathway Inactivation 25
MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells 42
Embryonic Stem Cells Markers SOX2， OCT4 and Nanog Expression and their Correlations with Epithelial Mesenchymal Transition in Nasopharyngeal Carcinoma 63
Aldehyde Dehydrogenase 1， a Functional Marker for Identifying Cancer Stem Cells in Human Nasopharyngeal Carcinoma 79
Neoplastic Spindle Cells in Nasopharyngeal Carcinoma Show Features of Epithelial-mesenchymal Transition 98
Gene Expression Profile Changes and Possible Molecular Subtypes in Differentiated-type Nonkeratinizing Nasopharyngeal Carcinoma 111
Target-specific Cellular Uptake of Taxol-loaded Heparin-PEGfolate Nanoparticles 128
GenCLiP： a Software Program for Clustering Gene Lists by Literature Profiling and Constructing Gene Co-occurrence Networks Related to Custom Keywords 145
Lentivirus-mediated RNAi Silencing Targeting ABCC2 Increasing the Sensitivity of a Human Nasopharyngeal Carcinoma Cell Line against Cisplatin 160
Identification of Label-retaining Cells in Nasopharyngeal Epithelia and Nasopharyngeal Carcinoma Tissues 173
An Imageable Metastatic Treatment Model of Nasopharyngeal Carcinoma 186
Frequent Hypermethylation of RASSF1A and TSLC1， and High Viral Load of Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma and Matched Tumor-adjacent Tissues 197
Proteome Analysis of Anti proliferative Mechanism of 12-O-Tetradecanoylphorbol 13-Acetate on Cultured Nasopharyngeal Carcinoma CNE2 Cells 211
Association of PLUNC Gene Polymorphisms with Susceptibility to Nasopharyngeal Carcinoma in a Chinese Population 226
Identification of Differentially Expressed Genes in Metastatic and Non-metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization 238
Identification and Characterization of a Novel Nasopharyngeal Carcinoma-associated Peptide： NAP-1 252
Construction of Tree Models for Pathogenesis of Nasopharyngeal Carcinoma 265
Identification of Differentially Expressed Genes in Nasopharyngeal Carcinoma by Means of the Atlas Human Cancer cDNA Expression Array 281
Molecular Cloning of a Novel Tissue-specific Gene from Human Nasopharyngeal Epithelium 294
Expression of an Epstein Barr Virus Receptor and Epstein Barr Virus Dependent Transformation of Human Nasopharyngeal Epithelial Cells 303
Analysis of DNA Fragments and Polymerase Chain Reaction Products from the Tx Gene by Capillary Electrophoresis with a Laser-induced Fluorescence Detector Using No-gel Sieving Media 315
Cytogenetic Study on a New Epithelial Cell Line， HNE-1， Derived from Nasopharyngeal Carcinoma 322
Chemical Transformation of Human Embryonic Nasopharyngeal Epithelial Cells in vitro 329
Establishment and Characterization of Two Epithelial Tumor Cell Lines （HNE-1 and HONE-1） Latently Infected with Epstein-Barr Virus and Derived from Nasopharyngeal Carcinomas 333
用曲细精管微注射法建立绿色荧光蛋白转基因小鼠 348
人鼻咽与鼻咽癌cDNA阵谱中DNA修复相关基因表达差异的初步研究 355
金属硫蛋白-潜伏膜蛋白融合基因的体外转录调控 360
鼻咽及其邻近部位各类型癌组织中EBV DNA的原位检测 368
体外培养人胚鼻咽上皮的生物学特性观察 Ⅰ人胚鼻咽上皮体外培养 373
从死因回顾调查资料看湖南省鼻咽癌流行病学的一些特点并探索其发病机理 378
二亚硝基哌嗪诱发大鼠鼻咽癌的进一步研究 385
三、姚开泰院士的重要学术报告 393
鼻咽癌研究的回顾与展望 393
陈竺等22位中国科学院院士联名向国务院提出建议 以非典型肺炎防治为切入点构筑我国预防医学创新体系 399
四、姚开泰院士学术年表 402
姚开泰院士担任第一作者或通讯作者SCI收录的英文论文 402
姚开泰院士担任第一作者或通讯作者非SCI收录的英文论文 407
姚开泰院士担任第一作者或通讯作者的中文论文 408
姚开泰院士参加工作的英文论文 422
姚开泰院士参加工作的中文论文 425
姚开泰院士获得的科研成果 429
姚开泰院士获得的荣誉称号 431
第三部分 治学之道 433
创建“中南大学肿瘤研究所” 435
第四部分 大师风范 439
姚老师对生物信息学的机敏 441
与姚老师相知 442
慕名从师 443
记姚老师二三事 444
与时俱进、诲人不倦的院士——记我的导师姚开泰教授 446
我和姚老师的师生情缘 447
第五部分 社会影响 449
姚开泰院士参加的学术活动、承担的科研项目、担任的学术职务 451
各大媒体对姚开泰院士的评价 454
姚开泰院士先进事迹 457
在姚开泰院士八十寿诞暨从医六十周年庆祝宴会上的讲话 459
与时俱进 克癌攻坚——记我国鼻咽癌病理研究专家姚开泰院士 461
第六部分 人生风采 465