生物化学PDF电子书下载

Chapter 1 Molecular Compositions of Proteins 1

1.1 Molecular Compositions of Proteins 2

1.2 Protein Structure 6

1.3 Protein Structure and Function 9

1.4 Protein Physicochemical Properties 12

1.5 Classification of Proteins 13

Chapter 2 Nucleic Acids 15

2.1 Nucleotides and Nucleic Acids 16

2.2 Spatial Structure and Function of DNA 18

2.3 Spatial Structure and Function of RNA 20

2.4 Physicochemical Properties of Nucleic Acids 22

Chapter 3 Enzymes 24

3.1 Structures and Properties of Enzymes 24

3.2 Enzymatic Kinetics 26

3.3 Regulation of Enzymes 30

3.4 Medical Aspects of Enzymes 31

Chapter 4 Metabolism of Carbohydrates 34

4.1 Overview 35

4.2 Glycolysis and Anaerobic Oxidation of Glucose 36

4.3 Aerobic Oxidation of Glucose 39

4.4 Pentose Phosphate Pathway 42

4.5 Gluconeogenesis 44

4.6 Glycogen Catabolism 46

Chapter 5 Lipid Metabolism 50

5.1 Overview 51

5.2 Triglyceride Metabolism 51

5.3 Phospholipid Metabolism 58

5.4 Cholesterol Metabolism 59

5.5 Lipid Transportation in Plasma 63

Chapter 6 Biological Oxidation 66

6.1 Electron Carriers and Electron Transport Chain 67

6.2 Oxidative Phosphorylation 70

6.3 Shuttle Systems 73

6.4 Mitochondrial Diseases 74

Chapter 7 Amino Acid Metabolism 76

7.1 Requirement of Protein/Amino Acids 77

7.2 Protein Digestion,Absorption and Putrefaction 78

7.3 Amino Acid Metabolic Pool 79

7.4 General Pathways of Amino Acid Catabolism 80

7.5 Metabolism of Individual Amino Acids 85

Chapter 8 Metabolism of Nucleotides 89

8.1 Metabolism of Purine Nucleotides 90

8.2 Metabolism of Pyrimidine Nucleotides 94

8.3 Conversion of Nucleotides 96

8.4 Nucleotide Metabolism Related to Medicine 97

Chapter 9 Regulation and Integration of Metabolism 100

9.1 Characteristics ofMetabolism 100

9.2 Interconversion of Metabolic Pathways 101

9.3 Regulation of Metabolisms 103

Chapter 10 DNA Biosynthesis 110

10.1 DNA-dependent DNA Synthesis(Replication) 111

10.2 RNA-dependent DNA Synthesis(Reverse Transcription) 117

10.3 DNA Damage and Repair 117

Chapter 11 RNA Biosynthesis 121

11.1 RNA Biosynthesis(Transcription) 122

11.2 RA Post-transcriptional Processing 131

Chapter 12 Protein Biosynthesis,Sorting and Targeting 137

12.1 Protein Synthesis System 138

12.2 Protein Synthesis in Prokaryotes 141

12.3 Protein Synthesis in Eukaryotes 143

12.4 Protein Sorting and Targeting 145

12.5 Clinical Relevancies of Protein Synthesis 147

Chapter 13 Biochemistry of Blood 150

13.1 Composition and Functions of the Blood 151

13.2 Plasma Proteins 152

13.3 Blood Cell Metabolism 154

Chapter 14 Biochemistry of the Liver 160

14.1 Metabolic Roles of the Liver 161

14.2 Biotransformation in the Liver 162

14.3 Metabolism of Bile Acids 164

14.4 Bile Pigment Metabolism 166