细胞生物学 英文PDF电子书下载

Chapter 1 Introduction to cell biology 1

1.1 What is cell biology? 1

1.2 The cell theory 2

1.3 Cell is the basic unit of life 4

1.4 The prokaryotic cell 7

1.5 The eukaryotic cell 8

1.6 Modern cell biology 11

1.7 The technology of cell biology 15

1.8 Training the scientists of tomorrow 19

Chapter 2 Cell membrane and cell surface 22

2.1 Components and structure of cell membranes 22

2.2 Transmembrane transport 30

2.3 Cell adhesion molecules and cell junction 39

2.4 Extracellular matrix and cell wall 44

Chapter 3 Cytoplasm,ribosomes and RNAs 49

3.1 Structure and functions of cytoplasm 49

3.2 Ribosome 52

3.3 Ribozyme 60

3.4 Non-coding RNA 62

Chapter 4 Endomembrane system,protein sorting and vesicle transport 67

4.1 Overview of endomembrane system 68

4.2 Endoplasmic reticulum 70

4.3 Golgi apparatus 80

4.4 Lysosomes and peroxisomes 83

4.5 Molecular mechanisms of vesicular transport 86

4.6 Secretory pathways 92

4.7 Endocytic pathways 95

Chapter 5 Mitochondria and chloroplasts 99

5.1 Mitochondria and oxidative phosphorylation 99

5.2 Chloroplasts and photosynthesis 108

5.3 The origins of chloroplasts and mitochondria 119

Chapter 6 Cytoskeleton 122

6.1 Microtubules 122

6.2 Actin filaments 129

6.3 Intermediate filaments 137

Chapter 7 Cell communication and signaling 142

7.1 Signaling components 142

7.2 The role of intracellular receptor:signaling of nitric oxide 148

7.3 Signaling through G-protein-coupled cell-surface receptors 149

7.4 Signaling through enzyme-coupled cell-surface receptors 154

7.5 Signal network system 159

7.6 Cell signaling and the cytoskeleton 161

7.7 Cell communication in plants 163

Chapter 8 Nucleus and chromosomes 166

8.1 The nucleus of a eukaryotic cell 166

8.2 The nuclear envelope 168

8.3 The nuclear pore complex 170

8.4 Chromatin and chromosomes 175

8.5 Nucleolus and ribosome biogenesis 186

8.6 The nuclear matrix 191

Chapter 9 Cell cycle and cell division 195

9.1 An overview of the cell cycle 195

9.2 Regulation of the cell cycle 197

9.3 Cell division 206

Chapter 10 Cell differentiation 221

10.1 Introduction 221

10.2 Cells with potency of differentiation 223

10.3 Stem cells 225

10.4 Controls of cell differentiation 229

10.5 The major cell differentiation systems 237

Chapter 11 Senescence and apoptosis 244

11.1 Senescence 244

11.2 Apoptosis 252

11.3 Senescence or apoptosis 260

Chapter 12 Cells in immune response 263

12.1 The immune system 263

12.2 The organs of the immune system 263

12.3 Cells in the innate immune system 266

12.4 Cells in the adaptive immune system 271

12.5 Innate and adaptive immune responses 273

12.6 Immunological memory 283

Chapter 13 Cancer cells 284

13.1 Basic knowledge about cancer cell 284

13.2 Carcinogenesis 288

13.3 The genes involved in cancer 292

13.4 The genetic and epigenetic changes of cancer 295

13.5 Treatment of cancer 299

References 303

Glossary 307