《The Physiology Of Induced Hypothermia》PDF下载

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  • 出 版 社:National Academy of Sciences-National Research Council
  • 出版年份:1956
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  • 页数:447 页
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PART Ⅰ-GENERAL PHYSICOCHEMICAL AND PHYSIOLOGIC CONSIDERATIONS OF HYPOTHERMIA 1

Some Considerations of Physicochemical Factors in Hypothermia&D.E.S.Brown 1

Effects of Hypothermia on General Metabolism&S.M.Horvath and G.B.Spurr 8

The Effect of Low Temperatures upon Intracellular Potassium in Isolated Tissues&I.M.Taylor 26

Potassium Exchange in Perfused Mammalian Skeletal Muscle&E.M.Renkin 32

Electrolyte Transfer during Hypothermia&Frank Gollan 37

Myocardial Balance of Potassium&Henry Swan 42

Effects of Low Body Temperature on Tissue Oxygen Utilization&E.F.Adolph 44

Oxygen Consumption of Mammalian Tissue at Reduced Temperatures&F.A.Fuhrman 50

Respiratory Physiologic Studies During Hypothermia&J.W.Severinghaus and M.Stupfei 52

The Gas Transport System in Hypothermia&F.F.Kao 58

Hypothermia in the Unanesthetized Poikilothermic Dog&A.D.Keller 61

Discussion:&A.C.Burton,J.W.Severinghaus,and J.Cahn 78

Physiology of Hibernation in Mammals&C.P.Lyman and P.O.Chat field 80

Discussion:&A.C.Burton,A.D.Keller;E.Calkins,G.E.Burch,J.D.McMurrey,H.Swan,C.McC.Brooks,and R.K.Andjus 122

Resuscitation and Recovery of Hypothermic,Supercooled,and Frozen Mammals&R.K.Andjus,J.E.Lovelock,and A.U.Smith 125

Discussion:&F.J.Lewis,J.W.Severinghaus,W.Parkins,A.L.Hopkins,J.Fine,R.W.Brauer,F.D.Moore,R.D.Dripps,and J.Henley 143

PART Ⅱ-THE EFFECTS OF HYPOTHERMIA ON SPECIFIC SYSTEMS 146

Cardiovascular Functions in Deep Hypothermia&H.E D'Amato 146

Discussion:&I.K.R.McMillan and E.Friedman 155

The Circulation During Rewarming&Henry Swan 161

Discussion:&R.O.Heimbecker and J.Fine 161

Coronary Blood Flow During Hypothermia&R.M.Berne 165

The Effect of Hypothermia on Pituitary ACTH Release and on Adrenal Cortical and Medullary Secretion in the Dog&D.M.Hume,R.H.Egdahl,and D.H.Nelson 170

Discussion:&A D.Keller,M.E.De Bakey,J.R.Pappenheimer,and F.D.Moore 173

The Effect of Hypothermia on the Peripheral Serum Levels of Free 17-Hydroxycorticoids in the Dog,and in Man&W.F.Bernhard 175

Discussion:&J.Cahn and H.Swan 178

Some Problems of Hematology in Hypothermia:An Introduction&William H.Crosby,Jr 183

The Effect of Hypothermia on Platelets and White Cells in Dogs&T.J.Villalobos,E.Adelson,and P.A.Riley 186

Discussion:&C.M.Couves,D.Warren,J.E.Rhoads,J.A.Helmsworth,and J.Adams-Ray 194

Renal Functional Response to Hypothermia and Ischemia in Man and Dog&J.H.Moyer,G.C.Morris,and M.E.De Bakey 199

Effect of Hypothermia on the Kidney&R.K.Andjus 214

Discussion:&P.A.Riley 218

Hypothermia and Temporary Occlusion of the Hepatic Circulation&N.E.Shumway and F.J.Lewis 221

Effect of Hypothermia on Metabolism and Drug Detoxification in the Isolated Perfused Rabbit Liver&I.Gray,R.R.Rueckert,and R.R.Rink 226

The Effect of Hypothermia on the Isolated Perfused Rat Liver&R.W.Brauer 235

Effects of Cold on the Nervous System&I.D.McQueen 243

Effects of Changes in Arterial pCO2 on Cerebral Blood Flow and Metabolism during Hypothermia&I.Kleinerman 251

Hypothermia and the Central Nervous System&H.L.Rosomoff 253

Hypothermia and the Nervous System&C.McC.Brooks 260

Experimental and Clinical Observations on the Use of Hypothermia to Prevent Ischemic Damage to the Central Nervous System&R.G.Pontius and M.E.De Bakey 264

Discussion:&W.H.Lougheed 270

Possibilities and Limitations of Differential Brain Cooling in Dogs&J.M.Jensen,W.M.Parkins,and H.M.Vars 271

Discussion:&W.M.Parkins,J.Cahn,and J.D.McMurrey 274

REVIEW AND APPRAISAL OF PARTS Ⅰ AND Ⅱ&J.W.Severinghaus 279

REVIEW AND APPRAISAL OF PARTS Ⅰ AND Ⅱ&S.M.Horvath 284

PART Ⅲ-MYOCARDIAL IRRITABILITY AND HYPOTHERMIA 287

Hypothermia and the Physiology of Cardiac Excitability&C.McC.Brooks 287

Temperature Effects on Cardiac Transmembrane Potentials&B.F.Hoflman 302

Discussion:&G.E.Burch,J.W.Severinghaus.and D.Durrer 324

Myocardial Irritability in Experimental Immersion Hypothermia&A.H.Hegnauer and B.G.Covino 327

Discussion:&F.J.Lewis,B.F.Hoffman,F.Gollan,A.Riberi,and J.Cahn 340

REVIEW AND APPRAISAL OF PART Ⅲ-C.McC.Brooks and B.F.Hoffman 355

PART Ⅳ-CLINICAL APPLICATION OF INDUCED HYPOTHERMIA 363

Hypothermia in Neurosurgery&E.H.Botterell and W.M.Lougheed 363

Discussion:&G.H.Clowes,Jr.,W.M.Lougheed,and E.H.Botterell 368

Effect of Hypothermia on Tolerance to Hemorrhagic Shock&E.W.Friedman,D.Davidoff,and Jacob Fine 369

Discussion:&E.Frank 378

Experimental Observations on the Influence of Hypothermia and Autonomic Blocking Agents on Hemorrhagic Shock&R.C.Overton and M.E.De Bakey 381

Hypothermia and Experimental Myocardial Infarction&Charles Huggim 392

Treatment of the Seriously Ill,Febrile Patient with Surface Cooling&F.J.Lewis,D.M.Ring,and J.F.Alden 394

Discussion:&W.J.Kolff,E.Calkins,H.Swan,F.J.Lewis,J.Henley,and C.W.Hughes 399

The Use of Hypothermia in Cardiac Surgery&Henry Swan 402

Discussion:&F.J.Lewis,J.H.Kay,I.K.R.McMillan,W.P.Longmire,Jr.,J.Cahn,C.W.Hughes,and H.Swan 409

REVIEW AND APPRAISAL OF PART Ⅳ&R.D.Dripps 413

PART Ⅴ-TECHNIQUES OF INDUCING HYPOTHERMIA 415

Problems in Methods of Inducing Hypothermia by Use of External Cooling&W.H.Muller,Jr.and J.F.Dammann 415

Problems in Methods of Inducing Hypothermia by Use of Drugs and Internal Cooling&J.F.Dammann and W.H.Muller,Jr 422

Discussion:&J.Adams-Ray,A.Riberi,R.O.Heimbecker,F.Gollan,R.W.Brauer,and L.I.Goldberg 430

REVIEW AND APPRAISAL OF PART Ⅴ&R.D.Dripps 439

Attendance 441

Index of Authors and Discussants 447