SECTION Ⅰ．INTRODUCTION 1
1．General Principles 1
SECTION Ⅱ．CENTRAL NERVOUS SYSTEM DEPRESSANTS 21
2．History and Theories of General Anesthesia 21
3．Stages of General Anesthesia 28
4．Preanesthetic Medication，Technics of Anesthesia，Anesthetic Accidents，and Properties of Ideal Anesthetics 40
5．General Anesthetics Ⅰ．Ether and Chloroform，Vinyl Ether，Ethyl Chloride，and Tri|chloroethylene 55
6．General Anesthetics (Continued) Ⅱ．Gas Anesthetics：Nitrous Oxide，Ethylene，and Cyclopropane 75
7．Basal Anesthetics 93
8．The Aliphatic Alcohols 98
9．Hypnotics and Sedatives Ⅰ．The Barbiturates 123
10．Hypnotics and Sedatives (Continued) Ⅱ．Bromide，Chloral Hydrate，Paraldehyde，and Miscellaneous Agents (Cannabis，Mescaline) 156
11．Drugs Effective in Convulsive Disorders 178
12．Centrally Acting Skeletal Muscular Relaxants 206
13．Natural and Synthetic Narcotics 216
14．Analgesics and Antipyretics Ⅰ．Salicylates and Congeners；Cinchophen and Congeners；Colchicine 281
15．Analgesics and Antipyretics (Continued) Ⅱ．Acetanilid and Acetophenetidin；Aminopyrine and Antipyrine 311
SECTION Ⅲ．CENTRAL NERVOUS SYSTEM STIMULANTS 324
16．Picrotoxin，Pentylenetetrazol，Nikethamide，Strychnine，and Camphor 325
17．The Xanthines Caffeine，Theophylline，and Theobromine 339
SECTION Ⅳ．LOCAL ANESTHETICS 354
18．Cocaine；Procaine and Other Synthetic Local Anesthetics 354
SECTION Ⅴ．DRUGS ACTING ON AUTONOMIC EFFECTOR CELLS 389
19．Anatomical，Physiological，and General Pharmacological Considerations 389
20．Drugs Stimulating Structures Innervated by Cholinergie Nerves (Parasympathomimetic Drugs) Ⅰ．Choline Esters 422
21．Drugs Stimulating Structures Innervated by Cholinergic Nerves (Parasympathomimetic Drugs) (Continued) Ⅱ．Cholinesterase Inhibitors and Anti-Curare Agents：Physostigmine，Neostigmine，Diisopropylfluorophosphate，Edrophonium，and Their Congeners 444
22．Drugs Stimulating Structures Innervated by Cholinergic Nerves (Parasympathomimetic Drugs) (Continued) Ⅲ．Pilocarpine，Arecoline，and Muscarine 470
23．Drugs Stimulating Structures Innervated by Adrenergic Nerves (Sympathomimetic Drugs) Ⅰ．Epinephrine and Levarterenol 476
24．Drugs Stimulating Structures Innervated by Adrenergic Nerves (Sympathomimetic Drugs) (Continued) Ⅱ．Ephedrine，Amphetamine，and Other Sympathomimetic Drugs 505
25．Autonomic Blocking Agents Ⅰ．Drugs Inhibiting Structures Innervated by Postganglionic Cholinergic Nerves 541
26．Autonomic Blocking Agents (Continued) Ⅱ．Drugs Inhibiting Structures Innervated by Adrenergic Nerves：Adrenergic Blocking Agents 570
27．Autonomic Blocking Agents (Continued) Ⅲ．Drugs Inhibiting Skeletal Muscles and Autonomic Ganglia 596
SECTION Ⅵ．HISTAMINE AND ITS ANTAGONISTS 644
28．Histamine and Antihistaminic Agents 644
SECTION Ⅶ．CARDIOVASCULAR DRUGS 668
29．Digitalis and Allied Cardinc Glycosides 668
30．Antiarrhythmic and Antifibrillatory Agents Quinidine and Procaine Amide 711
31．Vasodilator and Antihypertensive Agents Nitrites，Thiocyanate，Veratrum Alkaloids，Rauwolfia，Hydralazine，and Khellin 730
SECTION Ⅷ．WATER，SALTS，AND INOS 764
32．Agents Affecting Volume and Composition of Body Fluids 764
33．Cations：Potassium，Calcium，Magnesium，Barium，and Ammonium 795
34．Anions：Phosphate，Iodide，Fluoride，and Other Anions 835
SECTION Ⅸ．DRUGS AFFECTING RENAL FUNCTION AND ELECTROLYTE METABOLISM 840
35．Diuretics and Other Agents Employed in the Mobilization of Edema Fluid 840
36．Antidiuretics 869
37．Inhibitors of Renal Tubular Transport of Organic Compounds 880
SECTION Ⅹ．DRUGS AFFECTING UTERINE MOTILITY 886
38．Oxytocics Ergot，Ergot Alkaloids，and Posterior Pituitary 886
SECTION Ⅺ．GASES AND VAPORS 905
39．The Therapeutic Gases Oxygen，Carbon Dioxide，and Helium 905
40．Noxious Gases and Vapors Carbon Monoxide，Hydrocyanic Acid，and Miscellaneous Agents 926
SECTION Ⅻ．HEAVY METALS AND HEAVY-METAL ANTAGONISTS 939
41．Heavy-Metal Antagonists 939
42．Arsenicals 948
43．Mercury，Antimony，Gold，and Miscellaneous Metals 970
44．Lead 1002
SECTION ⅩⅢ．LOCALLY ACTING DRUGS 1017
45．Demulcents，Emollients，Protectives，Adsorbents，Hemostatics，Irritants，Astringents，and Certain Enzymes 1017
46．Gastric Antacids and Digestants 1029
47．Cathartics 1049
48．Emetics，Antiemetics，and Expectorants 1064
SECTION ⅩⅣ．ANTISEPTICS，DISINFECTANTS，AND DRUGS USED IN THE CHEMOTHERAPY OF INFECTIOUS DISEASES 1074
49．Antiseptics，Germicides，Fungicides，Virucides，and Ectoparasiticides 1075
50．Drugs Used in the Chemotherapy of Helminthiasis 1133
51．Drugs Used in the Chemotherapy of Malaria Quinacrine，Chloroquine，Chloroguanide，Pyrimethamine，Pamaquine，Primaquine，and Quinine 1161
52．Drugs Used in the Chemotherapy of Amebiasis Emetine，Halogenated Oxyquinolines，Organic Arsenicals，Chloroquine，and Fumagillin 1208
53．Miscellaneous Drugs Used in the Teatment of Protozoal Infections Diamidines and Suramin 1228
54．Penicillin Therapy of Syphilis 1233
55．Drugs Used in the Chemothernapy of Tuberculosis and Leprosy 1250
56．Sulfonamides 1276
57．Antibiotics Ⅰ．Penicillin 1321
58．Antibiotics (Continued) Ⅱ．Streptomycin and Dihydrostreptomycin 1360
59．Antibiotics (Continued) Ⅲ．The Tetracyclines：Chlortetracycline，Oxytetracycline，and Tetracycline 1378
60．Antibiotics (Continued) Ⅳ．Miscellaneous Antibiotics：Chloramphenicol，Erythromycin，Carbomycin，Polymyxin B，Neomycin，Bacitracin，and Tyrothricin 1394
SECTION ⅩⅤ．DRUGS USED IN THE CHEMOTHERAPY OF NEOPLASTIC DISEASE 1414
61．Cytotoxic Drugs，Hormones，and Radioactive Isotopes 1415
SECTION ⅩⅥ．DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS 1451
62．Drugs Effective in Iron-Deficiency Anemias 1451
63．Drugs Effective in Pernicious Anemia and Allied Megaloblastic Anemias Cyanocobalamin (Vitamin B12)，Liver Extract，and Folic Acid 1478
64．Anticoagulants Heparin and Bishydroxycoumarin，and Their Congeneric Substitutes 1500
SECTION ⅩⅦ．HORMONES AND HORMONE ANTAGONISTS 1528
65．Thyroid and Antithyroid Drugs 1528
66．Parathyroid 1566
67．Anterior Pituitary and Anterior Pituitary-Like Hormones 1573
68．Estrogens and progestogens 1589
69．Androgens 1609
70．Insulin 1620
71．Adrenocorticotropic Hormone and Adrenocortical Steroids 1642
SECTION ⅩⅧ．THE VITAMINS 1692
72．Water-Soluble Vitamins Ⅰ．The Vitamin B Complex 1692
73．Water-Soluble Vitamins (Continued) Ⅱ．Ascorbic Acid (Vitamin C) 1720
74．Fat-Soluble Vitamins Ⅰ．Vitamin A and Vitamin D 1728
75．Fat-Soluble Vitamins (Continued) Ⅱ．Vitamin K and Vitamin E 1746
Appendix Ⅰ．Principles of Prescription Writing 1759
Appendix Ⅱ．General Principles of Toxicology 1777
INDEX 1781