CHAPTER 1.Molecules and Life 1
Part Ⅰ CONFORMATION：exemplified by the relationship between the three-dimensional structure of proteins and their biological activity 9
CHAPTER 2.Introduction to Protein Structure and Function 11
CHAPTER 3.Oxygen Transporters：Myoglobin and Hemoglobin 46
CHAPTER 4.Hemoglobin：An Allosteric Protein 71
CHAPTER 5.Molecular Disease：Sickle-Cell Anemia 95
CHAPTER 6.Introduction to Enzymes 115
CHAPTER 7.Mechanisms of Enzyme Action：Lysozyme and Carboxypeptidase 153
CHAPTER 8.Zymogen Activation：Digestive Enzymes and Clotting Factors 178
CHAPTER 9.Connective-Tissue Proteins：Collagen and Elastin 206
CHAPTER 10.Introduction to Biological Membranes 227
Part Ⅱ GENERATION AND STORAGE OF METABOLIC ENERGY 255
CHAPTER 11.Metabolism：Basic Concepts and Design 257
CHAPTER 12.Glycolysis 277
CHAPTER 13.Citric Acid Cycle 307
CHAPTER 14.Oxidative Phosphorylation 331
CHAPTER 15.Pentose Phosphate Pathway and Gluconeogenesis 356
CHAPTER 16.Glycogen and Disaccharide Metabolism 378
CHAPTER 17.Fatty Acid Metabolism 404
CHAPTER 18.Amino Acid Degradation and the Urea Cycle 432
CHAPTER 19.Photosynthesis 456
Part Ⅲ BIOSYNTHESIS OF MACROMOLECULAR PRECURSORS 477
CHAPTER 20.Biosynthesis of Membrane Lipids and Steroid Hormones 479
CHAPTER 21.Biosynthesis of Amino Acids and Heme 503
CHAPTER 22.Biosynthesis of Nucleotides 528
Part Ⅳ INFORMATION：storage，transmission，and expression of genetic information 555
CHAPTER 23.DNA：Genetic Role，Structure，and Replication 557
CHAPTER 24.Messenger RNA and Transcription 594
CHAPTER 25.The Genetic Code and Gene-Protein Relationships 623
CHAPTER 26.Protein Synthesis 645
CHAPTER 27.Control of Gene Expression 679
CHAPTER 28.Eucaryotic Chromosomes 693
CHAPTER 29.Viruses 708
Part Ⅴ MOLECULAR PHYSIOLOGY：interaction of information，conformation，and metabolism in physiological processes 729
CHAPTER 30.Immunoglobulins 731
CHAPTER 31.Bacterial Cell Walls 754
CHAPTER 32.Membrane Transport 767
CHAPTER 33.Excitable Membranes 787
CHAPTER 34.Hormone Action 807
CHAPTER 35.Muscle Contraction and Cell Motility 826
Appendixes 843
Answers to Problems 847
Index 855