第一章 机体发育过程中的基因表达及同源异形基因盒 1
Chapter 1 Expression of Genes during Development and Homebox Gene 1
Differentiation of Embryonic Cell 2
胚胎细胞分化 2
Expression of Genes during Development 5
机体成形过程中的基因表达 5
Specific Expression of Genes in Adult Tissue 18
成体组织中基因的特异性表达 18
Modulation of Genes in Cell Differentiation 19
细胞分化的基因调控机制 19
Homebox Gene and Developing Nervous System 21
同源盒基因家族与神经系统发育 21
第二章 神经细胞的发育分化与神经系统发育中的基因调控 32
Chapter 2 Development and Differentiation of Neural Cells and Modulation of Genes in Developing Nerv 32
Neuroepitheliurn in Cell Circle 32
细胞周期中的神经上皮细胞 32
中枢神经系统神经元与神经胶质细胞的起源与分化 37
Origin and Differentiation of Neuron and Neuroglia in Central Nervous System 37
Modulation of Genes in Developing Nervous System 47
神经系统发育中的基因调控 47
胚盘中轴结构的形成 52
Formation of Axonal Structure in Embryonic Disk 52
Chapter 3 Development of Nervous System 52
第三章 神经系统的发生 52
Developmental Model of Developing Nervous System 53
神经系统发育分化的基本规律和模式 53
神经诱导与分化决定 54
Neural Indution and Determination 54
细胞粘附分子与神经发育 58
Neural Cell Adhesion Molecule and Neural Development 58
Morphogenesis of Nervous System 60
神经系统的发生 60
Chapter 4 Axonal Development 76
第四章 轴突的发育 76
细胞骨架 77
The Cytoskeleton 77
轴突运输 83
Axonal Transport 83
生长锥 86
The Growth Cone 86
Outgrowth of the Axon 89
轴突的长出 89
Single Transduction during Axonal Growth 95
轴突生长发育过程中的信息转导 95
Chapter 5 Dendritic Development and Formation of Synaptic Connections 98
第五章 树突的发育和突触的形成 98
Outgrowth of Dendrite 99
树突的生长发育 99
树突发育的时空规律 101
Time and Spatial Regulation of Developing Dendrite 101
Morphology of Dendritic Growth Cone 102
Morphology and Function of Dendritic Spine 102
树突生长锥的形态结构 102
树突棘的结构和功能 102
Cytochrome Oxidase Activity of Dendrite 105
树突的细胞色素氧化酶活性 105
Factors Influencing Growth of Dendrite 106
影响树突生长发育的一些因素 106
树突发育的稳定性 108
Developmental Stability of Dendrite 108
突触形成的一般概述 109
Introduction of Synaptic Formation 109
Program of Synaptic Formation 111
突触形成的程序性 111
Ultrastructural Defferentiation of Synapses 113
突触超微结构的分化 113
突触连接的地域分布特异性 115
突触的稳定性和适应性 115
Synaptic Stability and Lability 115
Topographical Specificity of Synaptic Connection 115
视觉刺激和视觉剥夺对突触形成的影响 116
Effects of Visual Stimultion and Deprivation on Formation of Synaptic Connection 116
蛋白质聚集素在突触形成中的作用 117
Role of Argine in Synapse Formation 117
概论 120
第六章 神经嵴及其衍生物 120
Introduction 120
Chapter 6 The Neural Crest and Its Derivatives 120
Developmental Process of Nreural Crest 124
神经嵴的发育过程 124
Basic Patterns of Neural Crest Development 133
神经嵴发育的基本方式 133
Factors Regulating Development and Differentiation of Neural Crest and Its Derivatives 134
神经嵴及其衍生物分化发育的调控因素 134
Regulating Model of Migration of Neural Crest Cells 136
神经嵴细胞迁移的调节模式 136
Control of Differentiation of Neural Crest Cells 137
神经嵴细胞分化的调控 137
脊髓感觉通路的胚胎发生及调控因素 138
Histogenesis of Spinal Sensory Pathway and Its Regulating Factors 138
Chapter 7 Neuroglial Cells 142
第七章 神经胶质细胞 142
Origin and Differentiation of CNS Macroglial Cells 144
中枢大胶质细胞的起源和分化 144
Astrocytes 145
星形胶质细胞 145
少突胶质细胞 156
Oligodendrocytes 156
小胶质细胞 163
Microglial Cells 163
Chapter 8 Histogenesis of Cerebral Neocortex 171
Schwann Cells 171
雪旺细胞 171
第八章 大脑新皮质的组织发生 177
Development of Cerebral Cortex:Overview 177
大脑皮质发育概况 177
Developmental Pattem of Ancestor Cells in Ventricular Zone of Telencephalon 178
端脑脑室层祖细胞的发生规律 178
Formation of the Cortical Preplate 181
早期胚胎皮质板的发生 181
大脑新皮质板层的组织发生 185
Histogenesis of Cerebral Cortical Plate 185
大脑皮质传入神经纤维的发生 188
Development of Cerebral Cortical Afferent Nerve Fibers 188
大脑皮质传出神经纤维的发生 191
Development of Cerebral Cortical Efferent Nerve Fibers 191
大脑皮质功能单位的发育 192
Development of Functional Units in Cerebral Cortex 192
视皮质神经回路的发生 196
Histogenesis of Neural-Circuit in the Optic Tecturn 196
General Overview of Retinal Canglion Cells 201
第九章 视网膜节细胞发育 201
视网膜节细胞概况 201
Chapter 9 Development of Retinal Ganglion Cells 201
视网膜节细胞的密度和分布 202
Density and Distribution of Retinal Ganglion Cells 202
视网膜节细胞的分类 203
Classification of Retinal Ganglion Cells 203
Arrangement of Dendrites of Retinal Ganglion Cells 208
视网膜节细胞树突的分层 208
视网膜节细胞的分化和发育 208
Development and Differentiation of Retinal Ganglion Cells 208
视网膜节细胞轴突投射的发育 212
Development of Axon Projections of Retinal Ganglion Cells 212
历史回顾 221
Historical Overview 221
Chapter 10 Programmed Neuronal Death and Its Occurring Mechanisms during Development 221
第十章 发育过程中的神经细胞编程性死亡及其发生机理 221
细胞凋亡的形态学与生化特征 222
Morpbological and Biochemical Characteristics of Cell Apoptosis 222
神经细胞编程性死亡的生物学意义 227
Biological Significance of Programmed Neuronal Death 227
神经细胞编程性死亡的发生机理 229
Occurring Mechanisms of Programmed Neuronal Death 229
细胞周期与细胞凋亡 238
Cell Cycle and Cell Apoptosis 238
老化与发育：对立的统一 243
Aging and Development;Opposite Unity 243
第十一章 脑的老化与老年性痴呆 243
Chapter 11 Brain Aging and Senile Dementia 243
脑的老化 246
Aging of Brain 246
生理性脑老化与老年性痴呆 250
Physiological Aging of Brain and Dementia 250
推迟脑衰老的对策 253
Counter Tactics of Postpone the Aging of Brain 253
Chapter 12 Neurotrophic Factors 259
第十二章 神经营养因子 259
The Family of Neurotrophic Factors 260
神经营养素家族 260
Ciliar Neurotrophic Factors 269
睫状神经营养因子 269
Astroglia-Derived Neuropholic Factors 272
胶质细胞系源性神经营养因子 272
已知的生长因子和细胞因子 273
Known Growth Factors and Cytokines 273
Neurotrophic Factors and Neural Degenerative Disease 279
神经营养因子与神经变性疾病 279
第十三章 中枢神经系统的可塑性 284
Chapter 13 Plasticity of Central Nervous System 284
视神经的可塑性 285
Plasticity of Optic Nerve 285
Plasticity of Spinal Cord 297
脊髓的可塑性 297
Chapter 14 Dependence of the Developing Nervous System on Nutrition and Hormones and Related Questio 304
第十四章 神经系统发育对激素与营养的依赖性及其他有关问题 304
Dependence of the Developing Nervous System on Nutrition and Hormones 305
神经系统发育对激素与营养的依赖性 305
Nitric Oxide and the Development and Regeneration of Nervous System 314
NO与神经系统的发育及再生 314
Transmitter Development of Neurons in Central Nervous System 325
中枢神经元的递质发育 325
学习、记忆与脑发育 336
Learning, Memory and Brain Development 336
Chapter 15 Transplantation and the Development and Regeneration of Central Nervous System 348
第十五章 脑内移植与中枢神经系统的发育再生 348
脑内移植研究的历史及现状 349
Historical Orientation of Transplantation 349
Functional Mechanisms of Transplantation 350
脑内移植物产生功能效应的机理 350
Transplantation of Nerve Tissue and the Development and Regeneration of Central Nervous System 353
神经组织移植与中枢神经发育再生 353
Recovery of Central Nervous Degenerative Disease by Transplantation of Nerve Tissue 356
神经组织移植修复中枢神经退行性疾病的研究 356
Chapter 16 Developing Nervous System and Tumor 370
第十六章 神经系统发育与肿瘤 370
Similarity of Fetus Development and Tumorgenesis 371
胚胎发育与肿瘤的相似性 371
Etiology and Etiopathogeneis Mechanism of Tumor 374
肿瘤的病因及致癌机理 374
Oncogene, Anti-Oncogene and Tumorgenesis 376
癌基因、抑癌基因与肿瘤发生 376
Sort and Physiological Function of Oncogene 378
癌基因的种类及生理功能 378
Oncogenes Related to the Development and Differention of Nervous System 380
与神经系统分化发育有关的癌基因 380
Genetic Tumor of the Centeral Nervous System Retinal Blastoma 381
神经系统遗传性肿瘤视网膜母细胞瘤 381
Other Tumors Related Fetus Development 382
神经系统其他的与胚胎发生有关的肿瘤 382
Introduction 384
Chapter 17 Methodology of Studying Tissue Development and Differentiation 384
第十七章 研究组织发育分化的一些实验技术 384
概述 384
Culture of Mouse Fetus after Transplantation 385
植入后小鼠胚胎的培养 385
Culture of Neural Plate, Crest, and Neural Tuble 390
神经板、神经嵴和神经管的培养 390
Subrenal Capsule Embryo Heterotopic Transplantation 392
肾被膜下间隙胚胎异位移植技术 392
Eye Anterior Heterotopic Transplantation 393
眼前房胚胎异位移植技术 393