细胞生物学PDF电子书下载

Chapter 1 Introduction to cell biology 1

1.1 What is cell biology 1

1.2 The cell theory 2

1.3 Cell is the basic unit of life 4

1.4 Diversity of cells 7

1.5 The prokaryotic cell 10

1.6 The eukaryotic cell 11

1.7 Morden cell biology 14

1.8 The technology of cell biology 20

1.9 Training the scientists of tomorrow 24

Chapter 2 Chemical components of cells 27

2.1 Chemical bonds 27

2.2 Organic molecules 36

Chapter 3 Biomembrane and cell surface 46

3.1 Components and structure of biomembranes 48

3.2 Plasma membrane 57

3.3 Transmembrane transport 63

3.4 Cell junction and adhesion molecules 77

3.5 Extracellular matrix and cell wall 83

Chapter 4 Intracellular compartments and transport 88

4.1 Organelles 88

4.2 Protein sorting inside cell 91

4.3 Molecular mechanisms of vesicular transport 97

4.4 Secretory pathways 100

4.5 Endocytic pathways 105

Chapter 5 Mitochondria and chloroplasts 110

5.1 Mitochondria and oxidative phosphorylation 110

5.2 Chloroplasts and photosynthesis 121

5.3 The origins of chloroplasts and mitochondria 130

Chapter 6 Cytoskeleton 133

6.1 Microtubules 133

6.2 Actin filaments 142

6.3 Intermediate filaments 152

Chapter 7 Cell communication and signaling 157

7.1 Signaling molecules and their receptors 157

7.2 Nitric oxide crosses the plasma membrane and actives intracellular enzymes directly 162

7.3 Functions of cell surface receptors 163

7.4 Signal network system 176

7.5 Cell signaling and the cytoskeleton 179

7.6 Cell communication in plants 181

Chapter 8 Nucleus and chromosomes 185

8.1 The nucleus of a eukaryotic cell 185

8.2 The nuclear envelope 188

8.3 Structure of the nuclear pore complex and its role in nucleocytoplasmic exchange 190

8.4 Chromosomes and chromatin 195

8.5 Nucleolus and ribosome biogenesis 208

8.6 The nuclear matrix 214

Chapter 9 Cell cycle and cell division 219

9.1 An overview of the cell cycle 219

9.2 Regulation of the cell cycle 221

9.3 Cell division 232

Chapter 10 Cell differentiation 250

10.1 Introduction 250

10.2 Cells with potency of differentiation 253

10.3 Stem cells 256

10.4 Epigenetic view of cell differentiation 262

10.5 The major cell differentiation systems 271

Chapter 11 Cell senescence and apoptosis 281

11.1 Senescence 281

11.2 Apoptosis 291

11.3 Senescence versus apoptosis 303

Chapter 12 Cells in immune system 306

12.1 The immune system 306

12.2 The organs of the immune system 307

12.3 Innate and adaptive immune systems 309

12.4 Innate immune system 311

12.5 Adaptive immune system 316

Chapter 13 Cancer cells 327

13.1 Basic knowledge about cancer cell 327

13.2 Carcinogenesis 332

13.3 The genes involved in cancer 335

13.4 The genetic and epigenetic changes of cancer 340

13.5 Diagnosis and treatment of cancer 347

References 353

Glossary 356