中西医结合心血管病基础与临床PDF电子书下载

第一章 冠心病血瘀证病证结合研究 2

冠心病血瘀证诊断标准研究 2

冠心病血瘀证血小板差异功能蛋白筛选、鉴定及功能分析 4

冠心病稳定期血瘀证与冠状动脉病变特点的相关性 11

冠心病差异基因表达谱的构建及目标基因的功能分析 14

汉族人血小板膜糖蛋白Ⅲa PLA基因多态性与冠心病血瘀证的相关性 20

汉族人血小板GPⅡb HPA-3基因多态性与冠心病的相关性研究 24

Correlation between Platelet Gelsolin Levels and Different Types of Coronary Heart Disease 28

Research on the Correlation between Platelet Gelsolin and Blood-Stasis Syndrome of Coronary Heart Disease 38

Aberrant Expression of FcγRⅢA （CD16） Contributes to the Development of Atherosclerosis 44

Investigation of Gene Expression Profiles in Coronary Heart Disease and Functional Analysis of Target Gene 51

Differential Gene Expression Profiles in Coronary Heart Disease Patients of Blood Stasis Syndrome in Traditional Chinese Medicine and Clinical Role of Target Gene 59

第二章 心血管瘀毒病因学研究 68

冠心病稳定期因毒致病的辨证诊断量化标准 68

冠心病稳定期“瘀毒”临床表征的研究 69

活血解毒中药配伍干预介入后不稳定型心绞痛的临床研究 73

活血解毒中药对稳定期冠心病患者血清炎症标记物及血脂的影响 77

Study on the Tongue Manifestations for the Blood-Stasis and Toxin Syndrome in the Stable Patients of Coronary Heart Disease 81

A New Potential Biomarker of “Toxin Syndrome” in Coronary Heart Disease Patient Identified with Proteomic Method 87

第三章 中西医结合防治心血管病的临床研究 102

第一节 中西医结合防治冠心病心绞痛 102

芎芍胶囊治疗冠心病心绞痛心血瘀阻证112例l临床研究 102

冠心病住院患者心血管事件的发生与中医证候分布规律研究 106

冠心病稳定期患者中医辨证与超敏C反应蛋白相关性研究 110

用复杂网络挖掘分析冠心病证候-治法-中药的关系 114

急性冠状动脉综合征中医证候要素分析 118

Analysis on Outcome of 5284 Patients with Coronary Artery Disease: The Role of Integrative Medicine 122

The Significant Increase of FcγR Ⅲ A （CD16）, A Sensitive Marker, in Patients with Coronary Heart Disease 130

The Expression of CD14+CD16+ Monocyte Subpopulation in Coronary Heart Disease Patients with Blood Stasis Syndrome 137

Combination of Chinese Herbal Medicines and Conventional Treatment versus Conventional Treatment Alone in Patients with Acute Coronary Syndrome after Percu-taneous Coronary Intervention （5C trial） : An Open-Label Randomized Controlled,Multicenter Study 144

Analysis on Outcome of 3537 Patients with Coronary Artery Disease: Integrative Medicine for Cardiovascular Events 154

The Effect of Sodium Tanshinone ⅡA Sulfate and Simvastatin on Elevated Serum Levels of Inflammatory Markers in Patients with Coronary Heart Disease: Study Protocol for a Randomized Controlled Trial 160

第二节 中西医结合防治心肌梗死及介入术后干预 171

益气养阴活血中药对急性心肌梗死患者血运重建后心室壁运动的影响 171

Protective Effect of Chinese Herbs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Heart Function of Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention 175

Clinical Outcomes and Cost-Utility after Sirolimus-Eluting versus Bare Metal Stent Implantation 183

A Multi-Center Randomized Double-Blind Placebo-Controlled Trial of Xiongshao Capsule in Preventing Restenosis after Percutaneous Coronary Intervention: A Subgroup Analysis of Senile Patients 192

Clinical Efficacy of Traditional Chinese Medicine on Acute Myocardial Infarction—A Prospective Cohort Study 198

Effect of Chinese Drugs for Supplementing Qi, Nourshing Yin and Activating BloodCirculation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization 205

Appraisal of the Prognosis in Patients with Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention 212

第三节 中西医结合防治高血压 219

病证结合治疗高血压病 219

波动性高血压与血小板活化及其中西医结合干预策略 222

清眩调压方治疗更年期女性高血压病的临床研究 225

补肾清肝方不同剂型对高血压阴虚阳亢证患者血压及血管紧张素Ⅱ水平的干预效应 230

清眩颗粒对伴及不伴睡眠呼吸暂停高血压患者内皮功能的影响 233

第四节中西医结合防治其他心血管病 238

慢性心力衰竭病证结合与临床治疗初探 238

中西医结合治疗心源性休克1例 240

第四章 中医药防治心血管疾病的药理研究 244

第一节 中医药防治心肌缺血／再灌注损伤的研究 244

西洋参茎叶总皂苷通过抑制过度内质网应激减轻大鼠心肌缺血／再灌注损伤 244

西洋参茎叶总皂苷通过抑制过度内质网应激减轻大鼠心肌细胞缺氧／复氧损伤 252

丹参、红花水溶性组分及配伍对大鼠心肌缺血／再灌注损伤作用的实验研究 259

益气活血中药联合缺血后适应保护缺血／再灌注大鼠心肌的机制研究 263

急性心肌梗死后大鼠缺血心肌胶原蛋白的表达及益气养阴活血和解毒活血中药的干预作用 269

芎芍胶囊联合缺血后适应对大鼠缺血／再灌注心肌MCP-1及TNF-α的影响 274

益气养阴活血配伍对缺血心肌差异基因表达的影响 278

莪术组分涂层支架预防猪冠状动脉再狭窄的研究 282

福辛普利钠预处理结合缺血后适应保护大鼠心肌缺血／再灌注损伤的研究 285

福辛普利钠预处理对缺血后适应大鼠心肌组织Toll样受体表达及炎症因子的影响 290

慢性应激抑郁对心肌梗死大鼠血管活性物质及炎症因子的影响 295

Panax Quinquefolium Saponins Reduce Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Excessive Endoplasmic Reticulum Stress 299

Effective Components of Panax Quinquefolius and Corydalis Tuber Protect Myocardium through Attenuating Oxidative Stress and Endoplasmic Reticulum Stress 309

Effects of Chinese Herbs Capable of Replenishing Qi, Nourishing Yin and Activating Blood Circulation and their Compatibility on Differentially Expressed Genes of Ischemic Myocardium 317

Ischemic Postconditioning through Percutaneous Transluminal Coronary Angioplasty in Pigs: Roles of PI3K Activation 323

Synergistic Protection of Danhong Injection and Ischemic Postconditioning on Myocardial Reperfusion Injury in Minipigs 330

Dynamic Expression of the Main Related Indicators of Thrombosis, Inflammatory Reaction and Tissue Damage in a Rat Model of Myocardial Infarction 336

第二节 中医药防治心室重构的研究 341

益气养阴与解毒活血中药对心肌梗死后大鼠早期心室重构心肌NF-KB和PPAR-γmRNA表达的影响 341

第三节 中医药促进血管新生的研究 346

人参和三七提取物在血管生成信号通路上作用靶点的实验研究 346

人参三七川芎提取物延缓衰老小鼠血管老化的实验研究 349

人参、三七提取物对Ras相关信号蛋白的影响 354

Effects of Active Components of Red Paeonia and Rhizoma Chuanxiong on Angiogenesis in Atherosclerosis Plaque in Rabbits 357

第四节 中医药防治动脉粥样硬化的研究 364

人参皂苷Rb1对氧化型低密度脂蛋白诱导的人单核细胞源树突状细胞免疫成熟的影响 364

赤芍川芎有效部位对兔动脉粥样硬化基质金属蛋白酶的影响 369

辛伐他汀对兔动脉粥样硬化斑块稳定性及斑块内血管新生的影响 373

Panax Quinquefolium Saponins Inhibited Immune Maturation of Human Monocyte-Derived Dendritic Cells via Blocking Nuclear Factor-KB Pathway 378

Effect of Chinese Drugs for Activating Blood Circulation and Detoxifying on Indices of Thrombosis, Inflammatory Reaction, and Tissue Damage in A Rabbit Model of Toxin-Heat and Blood Stasis Syndrome 387

Correlation between FcγRⅢA and Aortic Atherosclerotic Plaque Destabilization in ApoE Knockout Mice and Intervention Effects of Effective Components of Chuanxiong Rhizome and Red Peony Root 394

Effect of Simvastatin on the Atherosclerotic Plaque Stability and the Angiogenesis in the Atherosclerotic Plaque of Rabbits 400

第五节 中医药抗血小板、抑制血栓形成的研究 407

Correlation between Platelet Gelsolin and Platelet Activation Level in Acute Myocardial Infarction Rats and Intervention Effect of Effective Components of Chuanxiong Rhizome and Red Peony Root 407

Effect of Chinese Herbal Medicine for Activating Blood Circulation and Detoxifying on Expression of Inflammatory Reaction and Tissue Damage Related Factors in Experimental Carotid Artery Thrombosis Rats 416

第六节 中医药保护血管内皮细胞、抑制血管平滑肌细胞增殖的研究 422

活血解毒中药含药血清对氧化低密度脂蛋白诱导的内皮细胞损伤和凋亡的影响 422

人参三七组方对人脐静脉内皮细胞血管内皮生长因子分泌及其受体2表达的影响 427

人参三七川芎提取物延缓血管紧张素Ⅱ诱导内皮细胞衰老机制的研究 430

人参三七川芎提取物延缓内皮细胞复制性衰老的机制研究 435

Effect of Chinese Herbal Drug-Containing Serum for Activating-Blood and Dispelling-Toxin on Ox-LDL-Induced Inflammatory Factors' Expression in Endothelial Cells 439

Effects of Propyl Gallate on Adhesion of Polymorphonuclear Leukocytes to Human Endothelial Cells Induced by Tumor Necrosis Factor Alpha 443

第五章 糖、脂代谢异常的相关研究及其他 452

西洋参茎叶总皂苷对脂肪细胞糖脂代谢及胰岛素抵抗信号转导的影响 452

脂康颗粒与辛伐他汀降脂治疗随机对照研究 455

LC-ESI-MSn法鉴定心悦胶囊中西洋参皂苷类成分 459

Influence of High Blood Glucose Fluctuation on Endothelial Function of Type 462

Diabetes Mellitus Rats and Effects of Panax Quinquefolius Saponin of Stem and Leaf 464

Panax Quinquefolius Saponin of Stem and Leaf Attenuates Intermittent High Glucose-Induced Oxidative Stress Injury in Cultured Human Umbilical Vein Endothelial Cells via PI3K/Akt/GSK-3 β Pathway 471

Effect of Puerarin on the PI3K Pathway for Glucose Transportation and Insulin Signal Transduction in Adipocytes 480

Expression Changes of Akt and GSK-3β during Vascular Inflammatory Response and Oxidative Stress Induced by High-fat Diet in Rats 484

第六章 名老中医经验继承 492

陈可冀院士冠心病病证结合治疗方法学的创新和发展 492

传承岳美中教授崇高的人文精神遗产 495

岳美中教授病证结合治疗常见病的临证经验 496

基于关联规则的清宫胸痹医案用药规律研究 499

从治法入手探讨名老中医临床经验应用研究的思路和方法 502

郭士魁活血化瘀学术经验初探 504

翁维良应用活血化瘀法的学术经验 507

病证结合治疗观与临床实践 510

稳步促进中西医结合临床路径的实施 512

高敏心肌肌钙蛋白的临床应用：优势与挑战 513

2013年中美国家心血管病报告要点对比解读及其启示 515

稳定性冠心病：PCI还是药物治疗的选择——一项新的Meta分析结果的启示 521

2012年全球心肌梗死统一定义亮点解读 523

开拓心血管病领域中西医结合研究 526

病证结合治疗观的过去与现在 527

审慎对待合理应用冠心病介入治疗手段 534

中西医优势互补治疗冠心病心绞痛 536

病因病机研究与提高中西医结合临床水平 540

以临床实践数据为导向构建中西医结合临床指南的设想 541

病证结合治疗快速性心律失常经验举隅 545

病证结合临床研究的关键问题 546

推荐应用全球性心肌梗死新定义 548

多效药片（polypill）的临床应用与中成药的研发 550

心血管病临床治疗中存在的问题探讨 552

诊治心力衰竭学术思想及临证经验总结 558

《黄帝内经》体质分型与高血压发病关系初探 562

心主血脉与血栓前状态 565

Where Are We Going？ 567

The Potential Benefit of Complementary/Alternative Medicine in Cardiovascular Diseases 570

Complementary and Alternative Medicine: Is It Possible to Be Mainstream？ 571

Making Evidence-Based Decisions in the Clinical Practice of Integrative Medicine 573

Acupuncture: A Paradigm of Worldwide Cross-Cultural Communication 575

Herb-Drug Interaction: An Emerging Issue of Integrative Medicine 579

Integrating Traditional Medicine with Biomedicine towards a Patient-Centered Healthcare System 581

Chinese Medicine Pattern Diagnosis Could Lead to Innovation in Medical Sciences 584

New Findings Validate An Ancient Technique: How Massage Affects the Biochemistry of Inflammation 592

Reflections on the Research Status of Kampo Medicine : A Most Rewarding Visit to Japan 593

Profiles of Traditional Chinese Medicine Schools 598

第七章 综述与系统评价 604

病证结合的基础研究 604

中医和中西医结合临床指南制定的现状与问题 608

高血压中西医结合治疗研究的探索 612

关于高血压病的中西医结合研究 614

高血压血管内皮机制的中西医研究现状 615

西洋参茎叶总皂苷的心血管效应及其机制探讨 620

病证结合动物模型的研究进展 625

动脉粥样硬化及其中西医结合防治新策略 628

患者报告结局在中医药防治心血管系统疾病疗效评价中的应用与思考 632

抗血小板药物抵抗 635

关于急性冠状动脉综合征中无复流现象的防治 640

莪术及其提取物的心血管药理研究进展 641

延胡索碱治疗快速性心律失常的研究进展 644

川芎嗪的心脑血管系统药理作用及临床应用研究进展 648

转化医学与中西医结合的研究和发展 653

波动性高血糖与心血管并发症的关系 656

Atherosclerosis: An Integrative East-West Medicine Perspective 659

Atherosclerosis, Vascular Aging and Therapeutic Strategies 664

Systematic Review of Compound Danshen Dropping Pill: A Chinese Patent Medicine for Acute Myocardial Infarction 668

Chronic Intermittent Hypoxia and Hypertension : A Review of Systemic Inflammation and Chinese Medicine 687

Chinese Herb and Formulas for Promoting Blood Circulation and Removing Blood Stasis and Antiplatelet Therapies 694

Outcome Measures of Chinese Herbal Medicine for Coronary Heart Disease: An Overview of Systematic Reviews 705

Astragalus Injection for Hypertensive Renal Damage: A Systematic Review 716

A Systematic Review of Xuezhikang, An Extract from Red Yeast Rice, for Coronary Heart Disease Complicated by Dyslipidemia 723

Natural Polypill Xuezhikang : Its Clinical Benefit and Potential Multicomponent Synergistic Mechanisms of Action in Cardiovascular Disease and Other Chronic Conditions 744

Traditional Chinese Herbal Products for Coronary Heart Disease: An Overview of Cochrane Reviews 761

Tanshinone ⅡA: A Promising Natural Cardioprotective Agent 766

Clinical Significance of Inflammation Factors in Acute Coronary Syndrome from Pathogenic Toxin 776